Pregabalin Side Effects

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How to use Pregabalin? ( Lyrica) - Doctor Explains Side Effects 0 Views • 2 months ago

In this video we will cover everything you need to know about Pregabalin, also known as Lyrica. This video is part of a video series on mental health problems. So for more mental health related videos check out this playlist:
https://www.youtube.com/playli....st?list=PLaG3Bo3L0gX

Generic name: Pregabalin.
Brand names: Lyrica.
Available as a capsule and as a drink.

How to use it?
Capsule: make sure to swallow it whole with halve a glass of water. Do not break it and don’t chew on it, as this might decrease its effectivity.
Drink: make sure to measure the correct amount with a measuring spoon and drink it.

In addition, it is recommended to take Pregabalin at fixed times. This will make you less likely to forget a dose.

When to use it?
Pregabalin is part of a group of drugs called anti-epileptic drugs. However it can be used to treat several medical conditions, like:
- Epilepsy
- Neuropathic pain
- Generalized Anxiety Disorder

What is the correct dosage?
The precise dose will depend on your specific indication of use, the side effect you might experience and the severity of your symptoms.Therefore always use the precise amount and frequency your doctor prescribed you.

- When treating adults, the initial starting dose is usually 150mg/7,5ml per day divided over 2-3 doses. Based on individual response and tolerance, your doctor might slowly increase the dose up to 300 mg/15 ml per day. If needed this can be further increased up to a maximum dose of 600 mg/30 ml per day.

What are common the side-effects?
- Very common (10%): somnolence, dizziness and headache.
- Common (1-10%): euphoria, confusion, irritability, disorientation, insomnia, decreased libido, coordination problems, tremor, memory impairment, impaired concentration, balance disorder, blurred vision, dizziness, nausea, vomiting, diarrhoea, dry mouth, constipation, back pain, pain in limbs, erectile dysfunction, feeling drunk, fatigue and weight gain.
- Uncommon (0.1-1%): Hypersensitivity, decreased hunger, low blood sugar, restlessness, depression, agitation, aggression, mood swings, hallucinations, abnormal dreams, increased libido, panic attacks, loss of consciousness, cognitive impairment, speech disorder, eye pain, heart failure , low blood pressure, shortness of breath, itching, rash, muscle stiffness, fever and weight loss.
- Rare (0.01-0.1%): Allergic reactions, loss of vision, squint, palpitations, swallowing disorder, pancreatic inflammation, jaundice, Stevens-Johnson syndrome, renal failure and breast enlargement.
- Very rare (0.01%): liver failure and inflammation of the liver.

Safety:
First of all be careful to combine Pregabalin with alcohol. As this might increase its side effects.
In addition, it can be dangerous to drive while using this drug. As it can cause you to become drowsy, sleepy and/or dizzy. If you experiencing any of these side effects then please do not drive.
Furthermore, Pregabalin can have interactions with other drugs your are taking. always discuss this with your prescribing doctor.

Pregnancy and Lactation:
Research shows that use of Pregabalin can be dangerous when pregnant or when breastfeeding. However, there are some exceptions. Therefore always discuss this with your personal doctor.

- Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. -

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Literature:
1: Farmacotherapeutisch Kompas. (2021). Pregabaline.
2: Apotheek.nl (2021). Pregabaline.

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What is Pregabalin? London Pain Clinic Side Effects 0 Views • 2 months ago

Pregabalin (pre-GAB-a-lin) is an anticonvulsant drug prescribed for the management of neuropathic pain associated with diabetic peripheral neuropathy (DPN), post-herpetic neuralgia (PHN) and epilepsy.

As a consultant in pain medicine at the Imperial Healthcare NHS Trust in London and Medical Director of the London Pain Clinic http://www.londonpainclinic.com/ , Dr Chris Jenner works daily with patients who suffer from some of the most common, painful and yet misunderstood conditions to affect people around the world today.

Alongside a raft of professional qualifications and more than 15 years’ experience in the specialised field of pain medicine, Dr Jenner possesses a true passion for his subject, a fact which is not only evident through his commitment to using the very best cutting-edge treatments, but also through his desire to understand the impact of acute and chronic pain on the everyday lives of his patients.

Dr Jenner’s experience in treating conditions such as spinal pain, fibromyalgia and arthritis has led him to become one of the leading authorities in his field. Using a holistic approach and a variety of treatments which typically combine medication with minimally-invasive pain management procedures, he works with his patients to restore a pain-free existence, higher levels of physical function and a vastly improved quality of life.
Dr Jenner has several published books on related conditions, you can purchase them from Amazon on the below Links.

Arthritis: A practical guide to getting on with your life (How to Self-Help Guide)
https://www.amazon.co.uk/gp/product/1845284712?keywords=dr%20chris%20jenner&qid=1457818154&ref_=sr_1_2&sr=8-2
Fibromyalgia and Myofascial Pain Syndrome: A self-help guide
https://www.amazon.co.uk/gp/product/1845284674?keywords=dr%20chris%20jenner&qid=1457818142&ref_=sr_1_1&sr=8-1
Neck and Back Pain: A self-help guide (How to Self-Help Guide)
https://www.amazon.co.uk/gp/product/1845284682?keywords=dr%20chris%20jenner&qid=1457818154&ref_=sr_1_3&sr=8-3

In laymen terms, Pregabalin is a drug prescribed for relief from the diabetic nerve pain and used as an adjunct therapy for epilepsy patients with partial seizures and for generalized anxiety disorders.

Pregabalin is known to have a considerable impact on neuropathic lower back pain. Besides, an anticonvulsant is also known to reduce lower back pain with a considerably less amount of side effects than tricyclic antidepressants.

Marketed by Pfizer under the trade name Lyrica®, Pregabalin was developed as a follow-up drug to gabapentin and works by preventing or controlling abnormal increases in the brain electrical activity. While the European Union approved the drug in 2004, the US Food and Drug Administration (FDA) gave the approval for use a year later, in 2005.

http://www.londonpainclinic.com/antineuropathic-medication/pregabalin/

Should We Be Concerned about Weight Gain with Pregabalin (Lyrica®) for Restless Legs Syndrome (RLS)? Side Effects 1 Views • 2 months ago

Pregabalin (Lyrica®) is one of three medications in the class of seizure drugs known as alpha-2-delta ligands along with its cousins gabapentin (Neurontin®) and gabapentin enarcarbil (Horizant®) that are the consensus first-line drugs for the treatment of restless legs syndrome (RLS). @andyberkowskimd of ReLACS Health dissects the concerns about weight gain when it comes to taking pregabalin.

For background on pregabalin in the treatment of RLS, watch this video:
https://youtu.be/rGpzmFOQzSk

For more information on gabapentin and Horizant, this video explains the differences:
https://youtu.be/PPFw-W9unvw

Pregabalin has known side effects that can including dizziness or drowsiness, but weight gain is another important concern of RLS patients at ReLACS Health when discussing this treatment. Very little is known about how pregabalin causes weight gain. It could be increased appetite, negative effects on the body's metabolism, or even simply a gain in water weight. Regardless, the risks for some patients seem to be consistently present in studies, but the degree of the effect on those who have weight gain may also be small.

Much of the research on pregabalin is in those with epilepsy (seizure disorder) as this was one of the original uses for the drug.

As referenced in the video, here is a link to the Chen et al. (2015) with risk of weight gain from pregabalin in epilepsy of 8.4% in the studies reviewed:
https://www.epilepsybehavior.c....om/article/S1525-505

Cabrera et al. (2012) showed about 1/6 of patients had weight gain of grater 7% on pregabalin:
https://www.tandfonline.com/do....i/abs/10.1185/030079

This study from Poppen et al. on 77 veterans treated for 12-18 months for neuropathy with pregabalin with a weight gain of about 3 pounds:
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC82218

This systematic review by Panebianco et al. shows the risk is common but tends to increase with dose increases:
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC66149

This is important to those with RLS who may be taking 75-150 mg for RLS rather than as much as 600 mg/day for epilepsy.

Lastly, Hamandi et al. (2006) showed an average weight gain of 1-2 pounds and about 9% greater chance of weight gain over placebo in a few studies of pregabalin in epilepsy.

The bottom line is that weight gain is common but may not be severe. It also may not be bothersome at lower doses of pregabalin. As with all treatment interventions, one must weigh (pun intended) the risks of the unwanted effects with the treatment benefits. With increase in body mass from medications, small adjustments to lifestyle whether improved sleep, more exercise, reducing processed carbs and added sugars, etc. can go a long way to offsetting weight gain from pregabalin.

To read in more depth about RLS and other sleep disorders, follow A ReLACSing Blog:
https://www.relacshealth.com/blog

For those who live in or near Michigan, Ohio, or Florida, you can hire @andyberkowskimd as your own physician for advice on pregabalin, RLS, or any other aspect of sleep health. Go to https://www.relacshealth.com/ for more information.

Pregabalin: 5 Bad Side Effects of Pregabalin You Must Know Side Effects 0 Views • 2 months ago

Are you taking Pregabalin? Top 5 Bad Side Effects of Pregabalin You Must Know and How to Reduce Them. In today's video, we will learn about pregabalin, and the side effects of pregabalin 25mg, 75mg, 100mg, 150mg, 200mg, 225mg, and 300mg. and how to reduce the side effects.
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Other Videos to Watch:
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3 Powerful Drinks to Lower BLOOD PRESSURE Naturally:https://youtu.be/wOg3SNipFm0
Why Your BLOOD PRESSURE Reading is WRONG!: https://youtu.be/DBM1owhQ4D0
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Summary:
Are you taking Pregabalin or Lyrica? Pregabalin works by affecting the brain's chemical messengers to reduce pain signals in your nervous system. Doctors often prescribe Pregabalin to treat conditions like chronic nerve pain, diabetic neuropathy, shingles, or fibromyalgia. In this informative video, we will discuss the side effects of Pregabalin, how to ensure the medication's safety and effectiveness, and strategies for reducing these side effects. The dosages are pregabalin 25 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, and 300 mg.

Here are the side effects of pregabalin you should know:
0:00- Intro: What is pregabalin and how does it work?
0:50- Dizziness and Drowsiness
2:02- Weight Gain
2:52- Swelling in Hands and Feet
3:57- Vision Problems
4:53- Dry Mouth
6:46- Other Side Effects of pregabalin (fatigue, memory issues, headaches, constipation, joint pain, tremors, and withdrawal symptoms)

***Disclaimer:
This channel does not offer any medical advice. These videos and all comments are provided solely for educational purposes and are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Consult your doctor or another qualified healthcare provider if you have any questions about a medical condition. In addition, videos on this channel may contain information on the use of agents that have not been approved by the Food and Drug Administration of the United States (FDA). Dr. JedosaThePharmD does not advocate for the use of any unapproved agents.

Thanks for watching. I hope this video helps you understand and learn about pregabalin and the side effects of pregabalin 25mg, 75mg, 100mg, 150mg, 200mg, 225mg, and 300mg.