Metronidazole/Flagyl Toxicity, Adverse Effects & Thiamine Deficiency

Sun, 17 Aug 2025 21:20:22 +0000

In this video I discuss some of the side effects associated with a commonly prescribed antibiotic called metronidazole, also known as Flagyl.

In many, these adverse effects resolve with discontinuation of the drug. However, some people are left with longstanding illness which continues despite no longer taking this medication.

Research shows that metronidazole can readily convert into a thiamine (vitamin B1) analog which inhibits the activation of this vitamin inside the cell. Most of the symptoms of metronidazole toxicity are identical to neurological beri-beri and Wernicke's Encephalopathy, both conditions which are caused by deficiency of thiamine. Some researchers have concluded that this drug may "reinforce" or unmask an underlying insufficiency, triggering extreme symptom changes.

Many people report improvement in toxicity symptoms through using bioavailble forms of thiamine in conjunction with other B vitamins and magnesium supplementation.

Looking for guidance on addressing thiamine deficiency? Download my protocols here: https://thiamineprotocols.com/

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For a clean form of thiamine (TTFD), look to Objective Nutrients Thiamax: https://www.objectivenutrients.com/

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