Are the concerns about cyanocobalamin exaggerated?

Mon, 18 Aug 2025 11:46:27 +0000

Question: Are the concerns about cyanocobalamin exaggerated?

I'm not sure what people have said about the dangers. I know that I have been a critic of cyanocobalamin relative to other forms of B12 and then, other people may have used something I said maybe in an exaggerated way. And then there might be just much marketing that I haven't actually been exposed to where people have come up with their own marketing claims around other forms of B12.

So my opinion is basically as follows: number one, the amount of cyanide that would be released from taking even high doses of cyanocobalamin is very small. And so I don't think taking cyanocobalamin is dangerous in any context that I can think of so that's number one. But number two, one of our mechanisms for detoxifying cyanide, and it's not the only mechanism, but it's one of the key mechanisms is to join the cyanide, to cobalamin, to pee it out in the urine.

Reference: https://www.sciencedirect.com/....science/article/abs/

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.