#AmphotericinB #Echinocandins #Clotrimazole #Flucanazole #Voriconazole #Griseofulvin #Nystatin #LiposomalAmphotericinB #Antifungal

How to treat a fungal infection?
Mechanism of action of different anti fungal drugs?
Classification?
Side effects , uses etc

This video discusses the selective toxicity and pharmacology profiles of azoles, allylamines, griseofulvin and flucytosine of antifungal agents

Hey doctors! In this video, I review all of the Antifungals and associated pharmacology tested on Step 1. There's time at the end to screen shot the final diagram.

This is my first video ever, so leave any suggestions you have down below! I would love to hear from you guys.

Remember to work smarter not harder & good luck studying!


Credits:
Outro song: "Watch Me" by Jaden Smith

what are the side effects of Griseofulvin | what are the uses of Griseofulvin | griseofulvin uses
In this video you will learn about the uses and side effects of Griseofulvin. After watching this video you will be able to know about the uses and side effects of Griseofulvin. This video is very effective for those who don't know about the side effects of Griseofulvin and it uses.

This video gives overview about Antifungal Antibiotics- Amphotericin B, Nystatin, Caspofungin, Micafungin, Griseofulvin

Griseofulvin is an antifungal medication primarily used to treat dermatophyte infections, which affect the skin, hair, and nails. Here's an overview of its key aspects:

Mechanism of Action
Griseofulvin works by binding to keratin in the skin, hair, and nails, making these tissues resistant to fungal invasion. It also disrupts fungal cell division by interfering with microtubule function, which inhibits fungal growth.

Indications
Griseofulvin is effective against:

Tinea infections: Such as ringworm, athlete's foot (tinea pedis), and jock itch (tinea cruris).

Onychomycosis: Fungal infections of the nails.

Scalp infections: Caused by dermatophytes.

Dosage Forms
It is available in oral formulations, including:

Tablets.

Capsules.

Oral suspensions.

Side Effects
Common side effects include:

Nausea, vomiting, and diarrhea.

Headache and dizziness.

Skin rashes or photosensitivity. Rare but serious effects may include liver toxicity and allergic reactions.

Clinical Considerations
Griseofulvin is typically taken with fatty meals to enhance absorption.

It is contraindicated in patients with liver disease or porphyria.

Women should avoid pregnancy during treatment due to potential teratogenic effects.

#Griseofulvin

Griseofulvin

 Griseofulvin is a Heterocyclic Benzofuran antifungal Drug.

 Griseofulvin is fungistatic for most dermatophytes, including Epidermophyton, Trichophyton and Microsporum, etc., but not against Candida And other fungi causing deep mycosis.

It was one of the early antibiotics extracted from Penicillium griseofulvum. However, because of lack of antibacterial activity, little attention was paid to it: clinical utility in dermatophytosis was demonstrated only around 1960.

 

Mechanism

Griseofulvin binds to Tubulin (Protein in nucleus) interfering With microtubules function.

Griseofulvin inhibits fungal cell mitosis.

Griseofulvin gets deposited in Keratin forming cells of skin hairs, nails and protect Skin, hairs, nails from getting newly Infection.

The absorption of Griseofulvin from Gastrointestinal Tract it’s somewhat irregular because of its very low water solubility.

Absorption is improved by using Microfined particles and taking it with fatty food.

Route of administration – Orally only ( Tablet and Syrup )

Half life – 9-20 hours

Doses –

125–250 mg QID with meals; duration depends on the Site of infection (turnover rate of keratin).

Scalp 4 weeks

Palm, soles 6 to 8 weeks

Finger nails 6 to 8 months

Toe nails 10 to 12 months

Uses

 Superficial Dermatophytosis (Superficial Skin fungal Infections)

Tinea Corporis / Ringworm

-          Infection of the skin that can affect any part of the body excluding scale, face, beard and nail.

Tinea Barbae 

-         Fungal Infection of the beard and moustache areas.

Tinea Capitis

-         Fungal Infection of the skin of scalp, eyebrows.

Tinea Unguium / Onychomycosis

-         Fungal Infection of Nail

Tinea Pedis / Athlete’s foot

-         Fungal Infection between the toes

Tinea Cruris / Jock itch

-         Fungal Infection in the skin of the genital, inner, underarm and buttocks.

 

Side Effects

Nausea And Vomiting

Headache

Diarrhea

Sore throat

Mouth ulcer

Stomach upset

Skin Rash

Muscles pain

Decreased WBC count.

 

Contraindications and Warnings

Hypersensitivity to Griseofulvin or any component of formulation.

Pregnancy

Hepatic failure

Porphyria (Blood Disorders)

   WBC breakdown , Anemia

Avoid Alcohol

Griseofulvin | griseofulvin tablet uses,dose & side effects | griseofulvin in hindi

Welcome to our latest video on Griseofulvin, a powerful antifungal medication used to treat various fungal infections.
In this video, we will explore the uses, side effects, and precautions of Griseofulvin, as well as dosing and administration
guidelines. Whether you are a healthcare professional or someone seeking information on this medication,
our video will provide comprehensive and valuable insights. Don't forget to like, share, and subscribe for more
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Griseofulvin tablet| Grisovin tablets|griseofulvin 250 mg tablet uses,side effects,dose

Griseofulvin tablet is a heterocyclic benzofuranantifungal medicine. Griseofulvin tablet | grisovinfp tablets is available in different strength such asgriseofulvin 125 mg tablet | griseofulvin 250 mgtablet | griseofulvin 500 mg tablet.Griseofulvin tablet brand name are1. Grisovin fp tablets | grisovin fp 250 mg

2. Grisof tablet

3. Grisogen tablet

4. Grifulvin v tablet

5. Fulvicin p/g tablet

6. Ecovin tablet

7. Evafulvin tablet and many other.

Griseofulvin tablet | grisovin fp 250 mg uses totreat several types of fungal infection such as

1. Ringworm

2. Jock itch

3. Dermatophilosis

4. Nail fungal infection

5. Athlete's foot

6. Superficial skin fungal infection and many otherIn this video we learn about griseofulvin tabletcomplete information including

1. Griseofulvin tablet strength

2. Griseofulvin tablet brand name

3. Griseofulvin tablet uses in detail
1. Griseofulvin tablet strength

2. Griseofulvin tablet brand name3. Griseofulvin tablet uses in detail4. Griseofulvin tablet when not used5. Griseofulvin tablet contraindications6. Griseofulvin tablet side effects

7. Griseofulvin tablet dose | how to take and manymore in hindi.
Griseofulvin is an antifungal agent and chernicallyit is a spiro compound formed by fusion of1-benzofuran and cyclohexene rings at a singlecarbon. This drug acts by inhibition of mitosisat metaphase in fungal cells by actingmicrotubules. Due to high affinity to the keratincell this drug is specifically used for sin and nailinfections.
Griseofulvin tablet is a antifungal and antibioticmedicine. Griseofulvin oral tablet is used to treatfungal infections that can affect different parts ofyour body.

Griseofulvin tablet is available in different strengthsuch as 125 mg 250 mg and 500mg tablet.

Griseofulvin tablet | grisovin fp 250 mg uses totreat several types of fungal infection such asRingworm

Jock itch

fungal in hair

Nail fungal infection

Athlete's foot

And many more uses are there.

Griseofulvin tablet brand name are

Grisof tablet

Grisogen tabletGrifulvin v tablet

Grisovin FP

In this videos we discuss about the

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contraindications

doses

and more things.

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This video explains about Griseofulvin
Disclaimer: This video is for education purpose only, and is not intended as medical advice. While we try our level best for 100% accuracy, errors may occur, and medications or prescriptions, or protocols may change over time.

Griseofulvin Tablets Uses,Dose & Side Effects In Hindi / Grisovin Tab For Fungal Infection

Hi Friends Welcome To Gyanear The Medical Channel I Am Pharmacist Shivam Vishwakarma
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Griseofulvin is an antifungal agent and chemically it is a spiro compound formed by fusion of 1-benzofuran and cyclohexene rings at a single carbon. This drug acts by inhibition of mitosis at metaphase in fungal cells by acting on microtubules. Due to high affinity to the keratin cell this drug is specifically used for skin and nail infections.

#griseofulvin
#griseofulvintablet
#griseofulvin500mg

Griseofulvin is an antifungal medication that is primarily used to treat fungal infections of the skin, hair, and nails. It belongs to a class of drugs known as antifungals, and it is particularly effective against dermatophyte fungi, which are responsible for many common fungal infections of the skin and nails.

Here are some key points about Griseofulvin:

1. Mechanism of Action: Griseofulvin works by inhibiting the growth of fungi. It does this by disrupting the formation of the fungal cell wall, which is essential for the fungus's survival and replication. This mechanism of action makes it effective against a wide range of dermatophyte fungi.

2. Indications: Griseofulvin is typically prescribed to treat fungal infections such as ringworm (tinea corporis), athlete's foot (tinea pedis), jock itch (tinea cruris), and fungal infections of the nails (onychomycosis). It is also occasionally used for more severe fungal infections when other antifungal medications are ineffective.

3. Administration: Griseofulvin is usually available in the form of oral tablets or capsules. It is taken by mouth, typically with a fatty meal, as this enhances its absorption. The treatment duration can vary depending on the severity and location of the fungal infection but is often several weeks.

4. Side Effects: Common side effects of Griseofulvin may include gastrointestinal upset, such as nausea, vomiting, and diarrhea. It can also cause headaches, dizziness, and skin rashes. More serious side effects are rare but can include liver problems, blood disorders, and allergic reactions.

5. Precautions: Griseofulvin may interact with other medications, so it's important to inform your healthcare provider about any other drugs you are taking. It is typically not recommended for use during pregnancy or breastfeeding. Additionally, it can make some people more sensitive to sunlight, so sun protection is advised during treatment.

6. Effectiveness: Griseofulvin is generally effective for treating fungal infections caused by dermatophytes. However, it may not be the first choice for all infections, especially if newer antifungal medications with fewer side effects and shorter treatment durations are available.

7. Monitoring: While taking Griseofulvin, your healthcare provider may monitor your liver function with blood tests, as this medication can rarely cause liver problems.

It's important to note that Griseofulvin is a prescription medication, and its use should be supervised by a healthcare professional. If you suspect you have a fungal infection or have been prescribed Griseofulvin, it's essential to follow your doctor's instructions carefully and complete the full course of treatment to ensure the infection is effectively eradicated.