Bupropion (Wellbutrin) | The most versatile Antidepressant!

Fri, 15 Aug 2025 21:58:53 +0000

Bupropion is considered an atypical antidepressant. In today's video, we uncover the many ways Bupropion is used to not only treat depression but also used as smoking cessation treatment, weight loss, sexual dysfunction, and adjunctively with other antidepressants and mood stabilizers.

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Intro 0:00
Bupropion uses 0:15
Bupropion how it works 0:35
Side effects 1:10
Off-label uses 1:55
Non-addicting 4:25
Seizure risk 5:30
Cautions 6:56
Outro 7:38

Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own health care provider for proper diagnosis and treatment.

Resources:
Deprescribing Guide: https://amzn.to/4dZEUMk
Stahl's Prescribing Guide: https://amzn.to/3UXj8QL

Other Useful Videos:
Sertraline: 5 things you need to know https://youtu.be/L_7kTsbL7BU
Top Treatments for Major depressive disorder https://youtu.be/-JoTNsqyDxw

References:
Carlat, D. & Puzantian, T. (2020). Medication Fact Book for Psychiatric Practice, 5th ed.

Costa, R., Oliveira, N. G., & Dinis-Oliveira, R. J. (2019). Pharmacokinetic and pharmacodynamic of bupropion: integrative overview of relevant clinical and forensic aspects. Drug Metabolism Reviews, 51(3), 293–313. https://doi-org.libproxy.eku.e....du/10.1080/03602532.

Finkelstein, Y., Macdonald, E. M., Li, P., Mamdani, M. M., Gomes, T., & Juurlink, D. N. (2018). Second-generation anti-depressants and risk of new-onset seizures in the elderly. Clinical Toxicology (15563650), 56(12), 1179–1184. https://doi-org.libproxy.eku.e....du/10.1080/15563650.

Stahl, S. (2017). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 6th Ed.

Stahl, S. (2021). Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, 5th Ed.

Verbeeck, W., Bekkering, G. E., Van den Noortgate, W., & Kramers, C. (2017). Bupropion for attention deficit hyperactivity disorder (ADHD) in adults. The Cochrane database of systematic reviews, 10(10), CD009504.

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