Zoloft Side Effects


Sharing the pros and cons of Zoloft in today's video! Zoloft is a commonly prescribed antidepressant that belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). Like other antidepressants, it is generally considered to be effective in treating depression, anxiety, and other mental health conditions.
TIMESTAMPS:
0:00 Intro
0:19 What is Zoloft?
0:38 Benefits of Taking Zoloft
1:20 Cons of Zoloft
3:05 Bloopers
Some potential benefits of taking Zoloft include:
- It is generally well-tolerated by most people and has a relatively low risk of side effects.
- It can be effective in treating a wide range of mental health conditions, including depression, anxiety, and obsessive-compulsive disorder.
- It can be taken on a long-term basis to help prevent the recurrence of symptoms.
- It may also effectively treat some physical symptoms associated with mental health conditions, such as chronic pain or insomnia.
However, there are also some potential drawbacks to taking Zoloft, including:
- It may not be effective for everyone. Some people may not experience any improvement in their symptoms, or they may only experience a partial improvement.
- It can cause side effects in some people, such as nausea, dizziness, and sexual dysfunction. These side effects may be mild and go away on their own, but in some cases, they can be more severe and may require medical attention.
- It can interact with other medications, so it is important to tell your doctor about any other medications you are taking before starting Zoloft.
Overall, the decision to take Zoloft or any other antidepressant should be made in consultation with a doctor. Your doctor will be able to assess your individual situation and determine if Zoloft is the proper medication for you.
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Welloft a clever name for a medication combination commonly used in depression treatment. This view will discuss the mechanisms of each medication and explain why this combination might help improve depression more than other individual medications or combinations.
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Many people are too scared to start antidepressants once they have been prescribed. If you are worried about the side effects I hope you find support in this video and across my Channel; I have been in your shoes and remember being scared to start antidepressants when my GP asked me to start taking Sertraline. Has the road been easy? No. Has it been worth it? For me, absolutely. The main thing when starting antidepressants is to feel informed and safe. If you are worried about taking antidepressants then speak to your GP and allow them to talk you through the risks/rewards more carefully.
I was worried about the side effects of Sertraline but also the stigma surrounding taking antidepressants. I quickly found that whilst the side effects are real, the world can be an understanding place.
You are not alone in this journey, leave a comment describing your experience because you never know who it might help!
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#antidepressants #sertraline #zoloft
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Zoloft, Prozac, Celexa, Paxil, Lexapro and are all SSRI medication but you may prefer one vs the other and have a different reaction to each. This video explains what to expect and how to make a decision that helps you get better!
The most common form of antidepressant is known as an SSRI - Selective Serotonin Reuptake Inhibitor - if you want to know how this works I have a whole other video about that - right here! Depending on your source between 1 in 6 and 1 in 10 of the population are currently prescribed antidepressant and the vast majority of these will take an SSRI.
Video Contents:
00:00 - Introduction to video
01:00 - Different types of antidepressants - how do they work?
02:08 - What are the key differences between different antidepressants?
02:22 - The Half life of different antidepressant SSRIs
04:06 - Methods of consumption
05:07 - Dietary considerations about antidepressants
05:50 - Different genetic response to antidepressants
07:28 - How long will the antidepressants take to start working?
07:54 - Summary - how to choose the right antidepressant
SSRIs are all great at combating many mental health issues such as depression, general anxiety, PTSD, OCD etc. Which ever you take has the potential to significantly help your mental state.
The names listed at the start - Prozac, Zoloft, Celexa and so on are all SSRI medication so whilst they perform the same role in your body your individual reaction to different meds can be varied. So what are the differences?
The Key Differences
1. Half Life
2. Method of consumption
3. Dietary Considerations
4. Your own bodies reaction
Half Life
The Amount of time it takes for the amount of medication in the body to halve. Looking at this chart you can see this ranges considerably with SSRI medication. A shorter Half Life can mean that withdrawal is more of a shock to the system as the chemical change is more rapid; so whilst a longer half life med isn’t always the best choice it is useful knowledge if you decide to reduce your dosage and find withdrawal difficult. Moving to another SSRI with a longer half life can help this process.
A longer half life can also lead to less issues if you accidentally miss a dose. Your body won’t panic that you’ve gone ‘cold turkey’ quite as quickly.
Citalopram (Celexa) - 36 Hour Half Life
Escitalopram (Lexapro) - 30 Hour Half Life
Fluoxetine (Prozac) - 144 Hour Half Life
Paroxetine (Paxil, Pexeva) - 24 Hour Half Life
Sertraline (Zoloft, Lustral) - 36 Hour Half Life
Method of consumption
(e.g. Fluoxetine can be taken in liquid form that you simply drop into your mouth.)
People have preferences over how they take the meds. Some people hate swallowing pills and prefer something that dissolves in a glass of water. Some people prefer capsules to tablets. Each SSRI is available in different forms and if this element is an important part of you committing to taking it then speak with your GP. Likewise if you find yourself struggling with the method of consumption - raise it during your next medication review.
Dietary Considerations
(e.g Citlolapram contains lactose, fluoxetine capsules contains gelatine)
If you are lactose intolerant or vegan there might be dietary considerations to bear in mind.
Your Bodies Reaction
This is personal to you and difficult to predict. The Mayo Clinic recognises that your inherited traits i.e. your genetic makeup, play a role in determining how well your body reacts to different medication. You may have severe side effects with Prozac and find that Zoloft is an easier experience. If we understand that genetics plays a role here and you have close relatives who have taken antidepressants then asking about their experiences might help you and your GP find the right medication for you as your response may well be similar.
Your body will give you feedback about how things are going and it is up to you how you respond but consider the following:
ALL SSRIs are likely to cause some unpleasant side effects, particularly in the first couple of weeks.
It can take about 6 weeks before your body begins to feel the positive side effect.
If you feel confused about which antidepressant is right for you - you are not alone!
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Drugs that do a pretty good job of easing symptoms of depression and drugs that really help people struggling with obesity have a couple things in common. The first is that we have almost no idea how they work, and the second is that there’s often shame around using them because so many people view issues of mental health and weight control as personal failings. In a recent article for the New York Times I argue that we should shift focus from these two things and focus instead on significantly improving people’s lives, which these drugs do.
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I was on Zoloft for 2.5 years until it became time for me to produce my own euphoria. You'll be enlightened by my experiences with Zoloft, how an SSRI works, and all of those fun side effects. Throughout all my videos these were the most frequently asked questions. Thank you for checking this out!
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I've been taking Zoloft (Sertraline) 75mg every night for the last 1.5 years, and it's changed my life. In today's video i'll go over the ways it has helped, some of the negative side effects I've experienced, as well as what my plans are in terms of continuing to take Zoloft going forward. Mental Health Awareness is so important and something I'm passionate about. I've been able to talk to so many of you about your own experiences with anxiety and depression through sharing my journey, and I hope this video leaves you feeling like there are answers for your mental health out there, even if they aren't taking a medication like Zoloft (sertraline).
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In this video we will cover everything you need to know about Sertraline. This video is part of a video series on mental. So for more mental health related videos check out this playlist:
https://www.youtube.com/playli....st?list=PLaG3Bo3L0gX
Generic name: Sertraline.
Brand names: Zoloft.
Available as a tablet and drink.
How to use it?
Tablet: Swallow the tablet completely with half a glass of water. Don't break the tablet and don't chew on it.
Drink: Use a measuring cup or measuring spoon to measure the correct amount you need to take. Always mix it in a glass of water or lemonade. Then drink this immediately.
Duration of treatment?
The usual treatment takes 6-12 months. However if you are not experiencing any improvements after 3-4 months of use then you should contact your prescribing doctor. An other drug might be more suitable for you.
When to use it?
Sertraline is part of a group of drugs called SSRIs. It can be used to treat several mental health conditions:
- Depressive episode or the prevention of a depressive episode
- Panic disorder
- Obsessive Compulsive Disorder
- Social phobia
- Posttraumatic stress disorders
What is the correct dosage?
Always use the dosage and frequency prescribed by your own doctor.
- For depression or an obsessive compulsive disorder in adults: starting dose of 50mg once a day. At weekly intervals this can be increase with 50mg depending on your symptoms. Eventually up to a maximum dose of 200mg once a day.
- When treating a Panic disorder, Social phobia or Posttraumatic stress disorder: starting dose is usually 25mg once a day. After a week this is increased to 50mg once a day. If necessary the dosage can then be further increase with 50mg at weekly intervals, again up to a maximum dose of 200mg once a day.
What are the side-effects?
- Very common (more than 10%): insomnia, dizziness, fatigue, somnolence, headache, dry mouth, nausea and diarrhea.
- Common (1-10%): decreased appetite, agitation, anxiety, nervousness, depression, nightmares, decreased libido, tremor, lowered in concentration, hot flushes, yawning, abdominal pain, vomiting, constipation, rash, muscle pain and fever.
Safety:
You can combine sertraline with any type of food, however be careful when you combine it with alcohol. As this might increase the dazing effect of sertraline.
In addition it is usually safe to drive while using this drug, however it can cause you to become drowsy, sleepy and/or dizzy. If you experiencing any of these side effects then please do not drive.
Pregnancy and Lactation:
Sertraline can be dangerous in both cases, especially for pregnant women and their unborn babies. Therefore always discuss this with your prescribing doctor.
- Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. -
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Literature:
1: Farmacotherapeutisch Kompas. (2020). Loratadine.
2: Apotheek.nl. (2020). Sertraline.
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References:
Dhillon, S., Yang, L. P., & Curran, M. P. (2008). Bupropion: a review of its use in the management of major depressive disorder. Drugs, 68(5), 653–689. https://doi.org/10.2165/00003495-200868050-00011
Jing, E., & Straw-Wilson, K. (2016). Sexual dysfunction in selective serotonin reuptake inhibitors (SSRIs) and potential solutions: A narrative literature review. The mental health clinician, 6(4), 191–196. https://doi.org/10.9740/mhc.2016.07.191
Kassandra J. Gibbs, B. A., & J. Alexander Bodkin, M. D. (2016). Adjunctive Treatment Options for Patients With Residual Symptoms of Depression. Www.psychiatrictimes.com, 33. https://www.psychiatrictimes.c....om/view/adjunctive-t
Stahl,S. (2021). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 7th Ed.
Stahl, S. (2021). Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, 5th Ed.
Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own healthcare provider for proper diagnosis and treatment.
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This video describes how Zoloft or sertraline works. since sertraline is an antidepressant that belongs to the class called selective serotonin reuptake inhibitors (SSRIs), this overview can be extended to other medications in the same class like Prozac (fluoxetine), Paxil (paroxetine), Lexapro, and a few others.
Watch my full Zoloft (Sertraline) Review here - https://youtu.be/_N8QoNNuRM4


Get a doctors perspective on the medication Zoloft or Sertraline. Is it right for you? What side effects should you look out for? Learn about what conditions it works for including depression, anxiety, OCD, PTSD and severe form of PMS call PMDD. Learn how this medication can play a role in treating these conditions and some common as well as some rare side effects that can happen.
Zoloft (Sertraline) is in the family of medications called Selective Serotonin Reuptake Inhibitors (SSRI). They influence the amount of Serotonin that is available to help with mood and other functions of the body.
With depression you tend to have symptoms like difficulty concentrating, remembering things or making decisions. Fatigue, feelings of guilt, worthlessness, helplessness or hopelessness. People experience sleeping problems, mood swings, a loss of interest in things that you once enjoyed, appetite changes, generalized pain, persistent sad or empty feelings and even suicidal thoughts or attempts.
Those who are going through anxiety you may have symptoms such as sudden and unexplained onset of a rapid heart rate, sweating, trembling, shortness of breath, pain in your chest, fear of dying, numbness and tingling throughout your body or just a generalized feeling of anxiousness all the time that you just can’t explain.
If you are experiencing these symptoms you need to seek help from a professional. Go see your doctor and get an accurate diagnosis to figure out a good treatment plan for you. Remember depression and anxiety are real medical conditions and should be treated just as diabetes or high blood pressure need to be treated. You shouldn’t feel any different treating any one of these medical conditions.
We'll give a good overview in the video of the common side effects but its important to remember that most side effects if any are transient and can be minimized by working with your doctor. We will discuss more concerning side effects such as serotonin syndrome as well.
For other ideas on how to treat your depression may I suggest the following books:
The Happiness Advantage- Shawn Achor
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The Depression Cure: The 6-Step Program to Beat Depression without Drugs- Stephen S. Ilardi
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The Mindful Way Through Depression: Freeing Yourself from Chronic Unhappiness (Book & CD)- Mark Williams, John Teasdale et. al
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The Mindful Way through Anxiety: Break Free from Chronic Worry and Reclaim Your Life- Mark Williams, John Teasdale et. al
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The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time- Alex Korb PhD
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Dr. Pagnani of Rittenhouse Psychiatric Associates discusses Zoloft (sertraline) an SSRI or selective serotonin reuptake inhibitor. This medication is frequently used for patients struggling with anxiety disorders, major depression, OCD and bulimia.
Dr. Pagnani is the founder and medical director of Rittenhouse Psychiatric Associates, an Instructor at The Johns Hopkins Hospital for the Department of Psychiatry, he supervises psychiatric residents at Jefferson Hospital, he serves on the Young Professional Board of Uplift, the Center for Grieving Children and he maintains a private practice of Psychiatry in Philadelphia where he sees patients for one-time psychiatric evaluations and second opinions. He is a licensed physician and surgeon in NJ, PA, NY, MD, DE, FL and CA and can provide consultations to individuals via HIPAA compliant Telehealth visits living in these locations.
Rittenhouse Psychiatric Associates is a private practice of psychiatry consisting of about 25 psychiatrists, psychiatric nurse practitioners and psychotherapists with physical locations in Philadelphia and Paoli, PA and serving all of PA, NJ, NY and FL virtually via HIPAA compliant tele-psychiatry. Individuals seeking not only evaluations but long-term psychiatric care, can contact Rittenhouse Psychiatric Associates directly.
These videos aim to increase awareness and discussion of mental health topics and to encourage struggling individuals to schedule an appointment directly with a mental health provider. Mental health needs to be normalized, and simply speaking about mental health topics openly, is an important first step.
Dr. Pagnani and Rittenhouse Psychiatric Associates are NOT advocating for or against the use of any mentioned psychiatric medications for any specific individual. Additionally, any side effects mentioned are not a complete list of potential side effects or contraindications to taking any mentioned medications, and all risks and benefits of a medication should be discussed with an individual’s provider at an appointment, before starting, stopping or making changes to a medication regimen.
This video is INFORMATIVE ONLY - NOT MEDICAL ADVICE.
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