Lokelma Side Effects


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In this webcast, Drs. Eric Cannon and Darren W. Grabe discuss latest clinical data to evaluate the mechanism, safety, and efficacy of all available potassium binders and develop strategies to integrate this information into pharmacy protocols.
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El metoprolol es un bloqueador del receptor β₁ selectivo usado en el tratamiento de enfermedades severas del sistema cardiovascular, especialmente de la hipertensión y el infarto agudo de miocardio.
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هنتكلم عن كل المعلومات اللي لازم تعرفها قبل ما تستخدم دواء البلاكونيل أو الهيدروكسيكلوروكوين. هنتكلم عن مين اللي بيستخدمه، شكل الدواء، إزاي يتاخد، الأعراض الجانبية الشائعة والغير شائعة وكيف نحمي نفسنا منها.
ليه لازم نتابع مع طبيب العيون أو طبيب الرمد، وهنناقش آثاره على القلب واللي الناس اتكلمت عنها كتير في الفترة اللي فاتت بعد ما فشل في علاج فيروسات زي الكورونا.
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تحياتي
د. حمدي محمد عبد العزيز
الاستشاري
المصادر:
1- RECOVERY trial investigators. No clinical benefit from use of hydroxychloroquine in hospitalised patients with COVID-19. https://www.recoverytrial.net/....news/statement-from-
2- NIH halts clinical trial of hydroxychloroquine https://www.nih.gov/news-event....s/news-releases/nih-
3- WHO discontinues hydroxychloroquine and lopinavir/ritonavir treatment arms for COVID-19 https://www.who.int/news-room/....detail/04-07-2020-wh
4- WHO. “Solidarity” clinical trial for COVID-19 treatments: Update on hydroxychloroquine. https://www.who.int/emergencie....s/diseases/novel-cor
5- Baer AN, Witter FR, and Petri M, "Lupus and Pregnancy," Obstet Gynecol Surv, 2011, 66(10):639-53
6- Bahloul E, Jallouli M, Garbaa S, et al. Hydroxychloroquine-induced hyperpigmentation in systemic diseases: prevalence, clinical features and risk factors: a cross-sectional study of 41 cases. Lupus. 2017;26(12):1304‐1308.
7- Balevic SJ, Cohen-Wolkowiez M, Eudy AM, Green TP, Schanberg LE, Clowse MEB. Hydroxychloroquine levels throughout pregnancies complicated by rheumatic disease: implications for maternal and neonatal outcomes.
8- Birru Talabi M, Clowse MEB. Antirheumatic medications in pregnancy and breastfeeding
9- https://www.accessdata.fda.gov..../drugsatfda_docs/lab


At the National Kidney Foundation Spring Clinical Meetings, Matthew R. Weir, MD, spoke about results of a study that measured the efficacy and safety of Veltassa for patients with hyperkalemia.
The results presented in a poster here were from a pooled analysis of 653 patients from the OPAL-HK, AMETHYST-DN and TOURMALINE phase 3 clinical studies. Overall, 98% of the patients had hypertension and 93% of patients were taking renin-angiotensin-aldosterone system (RAAS)-inhibitor therapy.
Weir said results demonstrate the utility of the new approach to control hyperkalemia, as Veltassa (patiromer, Relypsa Inc.) consistently reduced potassium levels in the patients studied, including patients on RAAS-inhibitor therapy.
See more Nephrology videos at https://www.healio.com/nephrology/news/video


Explore bicarbonate's pivotal role in treating hyperkalemia, a condition marked by high potassium levels in the blood. We'll examine how bicarbonate helps lower potassium levels and the benefits and potential side effects of this treatment.
SIMILAR VIDEOS
Kayexalate: https://youtu.be/0uAd8upTtZU
Furosemide: https://youtu.be/F9Xor5Ml8yY
Calcium: https://youtu.be/2Xus7HVYmKM
Insulin: https://youtu.be/6wDoHHySnng
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⚠️ For Healthcare Practitioners: This content is provided only for medical education. Although the authors have made every effort to provide the most up-to-date, evidence-based medical information, this content should not necessarily be considered the standard of care. It may not reflect individual practices in other geographic locations. It should be considered in the context of other medical educational resources.
⚠️ For the Public: This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. You should contact your own physician or other qualified healthcare providers with any questions you may have regarding your medical condition. Do not disregard professional medical advice or delay seeking it based on information from this content. Relying on information provided in this content is done at your own risk. In a medical emergency, contact your physician or call 9-1-1 immediately.


SHA Lokelma the New Path for Hyperkalemia Management (12th Feb 2022)
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Please see Important Safety Information and Full Prescribing Information:
https://spr.ly/LOKELMASafetyInformation.
High potassium (hyperkalemia) is when levels are higher than normal, which are above 5.0 mEq/L. Learn about the potential risks of not treating hyperkalemia as prescribed and what you can do to lower your K⁺ levels.


ジルコニウムシクロケイ酸ナトリウム水和物
ロケルマって何の薬?
ロケルマの飲み方は?
ロケルマの効能効果は?
ロケルマの副作用は?
▶このビデオを他のユーザーと共有する: https://youtu.be/KLi0keMpzrU
▶ 購読してHe-infoの詳細をご覧ください: https://www.youtube.com/c/HeInFo123
#ジルコニウムシクロケイ酸ナトリウム水和物
#zirconium
#ロケルマ
#lokelma
#アストラゼネカ
___________________________________________________
好き、共有、購読することを忘れないでください#He-info
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Dr. Biff F. Palmer, a Professor of Medicine at the University of Texas Southwestern Medical Center in Dallas TX., reviews his article appearing in the February 2020 issue of Mayo Clinic Proceedings, where he discusses the benefits of two newly approved treatments for hyperkalemia: sodium zirconium cyclosilicate and patiromer. These appear to allow better maintenance of normal kalemia and may also ease the dietary restrictions on potassium containing foods (which are generally hearth healthy) for patients with chronic kidney disease.
Available at: https://mayocl.in/35IgUK5


Please see Important Safety Information and Full Prescribing Information:
https://spr.ly/LOKELMASafetyInformation.
Learn about high potassium (hyperkalemia), find savings and support, and ask your doctor how you can best manage high levels of potassium.


Kayexalate, a crucial medication used for treating high potassium levels in the blood. We'll break down how it works, its dosage, pharmacology, and side effects so you can understand it.
SIMILAR VIDEOS:
Insulin: https://youtu.be/6wDoHHySnng
Calcium: https://youtu.be/2Xus7HVYmKM
Furosemide: https://youtu.be/F9Xor5Ml8yY
DISCLAIMER
⚠️ For Healthcare Practitioners: This content is provided only for medical education. Although the authors have made every effort to provide the most up-to-date, evidence-based medical information, this content should not necessarily be considered the standard of care. It may not reflect individual practices in other geographic locations. It should be considered in the context of other medical educational resources.
⚠️ For the Public: This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. You should contact your own physician or other qualified healthcare providers with any questions you may have regarding your medical condition. Do not disregard professional medical advice or delay seeking it based on information from this content. Relying on information provided in this content is done at your own risk. In a medical emergency, contact your physician or call 9-1-1 immediately.
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Here’s what you need to know about psyllium husks. Check this out.
DATA:
https://www.sciencedirect.com/....topics/medicine-and-
https://www.ncbi.nlm.nih.gov/pubmed/21082352
Best Natural Laxatives:
https://youtu.be/WuyyXsGdFyQ
Timestamps
0:07 What are psyllium husks?
0:26 Psyllium husks uses
0:29 Psyllium husks benefits
0:49 Psyllium husks dosage
0:58 Psyllium husks side effects
In this video, I’m going to cover what you need to know about psyllium husks.
What are psyllium husks?
Psyllium seed husks come from a plant called plantago ovata. Out of all of the fibers, psyllium has the most soluble fiber.
Psyllium husks uses:
Psyllium husks are mainly used as a natural laxative.
Psyllium husks benefits:
• It may be good for constipation
• It may be good for irritable bowel syndrome (IBS)
• It may be good for high blood pressure
• It may be good for heart disease
• It may be good for diabetes
• It may be good for cholesterol
How to use psyllium husks:
The amount you may want to consider taking would be about 7 grams per day. Mix this water and drink up. You want to make sure to drink more water to help decrease the potential side effects of psyllium husks.
Psyllium husks side effects:
• Gas
• Abdominal bloating
• Diarrhea
• Constipation
• Nausea
• Headaches
• Allergy
• Decreasing iron
• Decreasing B2
• Decreasing the absorption of fat
Dr. Eric Berg DC Bio:
Dr. Berg, 56 years of age is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of The New Body Type Guide and other books published by KB Publishing. He has taught students nutrition as an adjunct professor at Howard University. He no longer practices, but focuses on health education through social media.
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Disclaimer:
Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients so he can focus on educating people as a full time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.


Numerous drugs used to manage and treat multiple diseases, including hypertension, diabetes, and other pathologies, can be harmful to the kidneys and are referred to as nephrotoxic medications.
In this video, I highlight 5 of those medications.
Link to article from The Kidney Foundation on herbal supplement use in chronic kidney disease - https://www.kidney.org/atoz/content/herbalsupp


Hyperkalemia (high potassium levels in your blood) is a very dangerous condition, especially in patients having kidney diseases. It is a fatal condition that can even cause death. But if you know the signs and symptoms of high potassium levels in your blood, you can save your or someone else’s life. So in this video, we’ll tell you all the hyperkalemia
symptoms you should be aware of.
#HyperkalemiaSymptoms #signsOfHighPotassium #HighPotassiumSymptoms
OTHER VIDEOS SUGGESTED FOR YOU
6 signs you have a potassium deficiency
https://youtu.be/Grlk4tDt10M
8 Signs Of Low Blood Sugar And How To Treat It
https://youtu.be/66nRImvQxOA
TIMESTAMPS
Intro - 0:00
Muscle weakness - 1:54
Numbness and tingling - 2:29
Nausea and vomiting - 2:52
Abnormal heartbeat - 3:08
Shortness of breath - 3:57
How to check the potassium levels in your blood - 4:57
Conclusion - 5:34
SUMMARY
1. Muscle weakness: Hyperkalemia is characterized by ascending muscle weakness that begins with the legs and progresses to the trunk and arms. This is one of the very important signs of high blood potassium levels. Simple activities such as walking will make you feel weak. Your muscles can also lose their ability to function properly, leading to fatigue. You may have dull, continuous pain in your muscles. It may feel as if you have completed a strenuous workout or a physical exercise when you have just started your day.
2. Numbness and tingling: Having too much potassium in your blood also affects nerve function. Potassium helps you fire signals in your brain. But this becomes harder when there is too much potassium in your blood. Gradually you may develop neurological symptoms such as numbness or a feeling of “pins and needles” striking your limbs.
3. Nausea and vomiting: Hyperkalemia can also have a detrimental effect on your digestive health. In some people, too much potassium has been linked to vomiting, nausea, and abdominal pain.
4. Abnormal heartbeat: A side effect of hyperkalemia is the risk of developing an abnormal heartbeat. This occurs when damage occurs to the muscles that control your heart. This can cause heart palpitations, chest pain, and lead to heart failure. Your heartbeat may feel like your heart has stopped beating. This feeling is not only felt in the chest. Some people feel a tingling sensation in the neck and throat, too. If you have a heart rhythm problem, you may feel a strong pressure on your chest, arms, and neck. Other symptoms such as diarrhea, heartburn, cold sweats, and dizziness may also occur. If you experience these symptoms, call 911 or seek immediate medical attention.
5. Shortness of breath: Breathing problem is another indication of high potassium levels. This occurs when high blood potassium begins to affect the muscles that control breathing. Your lungs do not get enough oxygen because of the increased heart rate. You may have difficulty holding your breath or feeling tightness in your chest. In extreme cases, it may feel as if you were being choked. Call your doctor and seek medical help as soon as possible in case you feel this.
Most people have a few symptoms. When symptoms appear, they are usually mild and vague. You may feel muscle weakness, numbness, tingling, nausea, or other unusual sensations. It usually grows slowly for several weeks or months and is usually mild. It can come back.
Sudden or severe hyperkalemia is a life-threatening condition. It requires immediate medical attention.
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How Does Sodium Zirconium Cyclosilicate (Lokelma) Work? In this informative video, we will discuss Sodium Zirconium Cyclosilicate, commonly known as Lokelma, and its role in treating high potassium levels in the blood, a condition referred to as hyperkalemia. We will explain how Lokelma works by binding potassium ions in the gastrointestinal tract, facilitating their elimination through feces. This mechanism is essential for managing elevated potassium levels effectively and safely.
You’ll learn about Lokelma's unique properties, including its non-absorbed nature and its ability to selectively capture potassium ions without affecting other electrolytes. We will also highlight the significance of Lokelma's rapid action, which can be particularly beneficial in emergency situations. Understanding the application of Lokelma in both immediate treatment and long-term management of hyperkalemia is important for healthcare providers and first responders alike.
Join us as we break down the science behind this medication and its practical implications in the field of emergency medicine. Don't forget to subscribe to our channel for more helpful discussions on first responders medicine and related topics.
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#Hyperkalemia #Lokelma #SodiumZirconiumCyclosilicate #EmergencyMedicine #FirstResponders #PotassiumLevels #MedicalTreatment #GastrointestinalHealth #PotassiumBinder #CriticalCare #PatientCare #ElectrolyteBalance #HealthEducation #Pharmaceuticals #MedicalKnowledge
About Us: First Response Medicine is your essential resource for all things related to emergency and critical care. Our channel is dedicated to providing clear and practical information on emergency medicine, covering topics such as trauma management, life-saving procedures, and the latest in critical care practices.
Please note that all content is for informational purposes only and should not be considered medical advice. Always conduct your own research and consult with professionals when necessary. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.


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"This video provides educational content for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider with any questions regarding a medical condition or treatment. We do not endorse any specific treatments, medications, or products discussed on this channel."
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In this video, we discuss the symptoms and causes of high potassium, also known as hyperkalemia. Potassium is an essential mineral that helps regulate heart rhythm and muscle function, but when levels get too high, it can lead to serious health problems. Learn about the common symptoms of hyperkalemia and what causes high potassium levels, such as kidney disease, medication use, and dietary factors.
Read more about high potassium (hyperkalemia): https://www.kidney.org/atoz/co....ntent/what-hyperkale
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What do high blood potassium levels (hyperkalemia) mean, and what can you do about this situation? Find out.
DATA:
https://www.exatest.com/
Timestamps
0:00 High blood potassium levels (hyperkalemia)
1:20 Hyperkalemia causes
2:30 Typical hyperkalemia treatment
3:05 Hypokalemia
3:20 Symptoms of hypokalemia
3:30 Testing for hyperkalemia and hypokalemia
Today we’re going to talk about high levels of potassium in your blood, which is called hyperkalemia.
98% of all of the potassium in your body is actually inside of your cells, not outside of the cells or in your blood. When evaluating hyperkalemia, we’re really looking at just the 2%, so we’re not seeing the whole picture of what’s going on.
Considering that the majority of the potassium is inside of the cell, measuring potassium levels based on the blood may not be a good way to determine if a person has too much or too little potassium. However, there is an intracellular potassium test that I believe is much more valuable.
A few important things about hyperkalemia:
• It’s very rare
• There are very few symptoms associated with hyperkalemia (severe cases may cause palpitations, tiredness, muscle pain, and muscle weakness)
• There is a condition called pseudohyperkalemia (which is basically a false impression that you have high levels of potassium in the blood)
• Excessive intake of potassium is not a primary cause of hyperkalemia
A few causes of hyperkalemia:
• Advanced kidney disease
• Addison’s disease
• NSAIDs
• Certain high blood pressure medications
The typical treatment for hyperkalemia typically involves taking:
• Calcium
• Insulin
• Dextrose
• Sodium bicarbonate
On the other hand, A deficiency of potassium in the blood is called hypokalemia. Hypokalemia is the most common form of electrolyte imbalance when someone is hospitalized.
A few symptoms of hypokalemia:
• Leg cramps
• Weakness
• Constipation
• Abnormal heart rhythm issues
Dr. Eric Berg DC Bio:
Dr. Berg, age 58, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.
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Disclaimer:
Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients so he can focus on educating people as a full time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.
#keto #ketodiet #weightloss
Thanks for watching! I hope this helps you better understand high blood potassium levels (hyperkalemia).


What Are The Side Effects Of Sodium Zirconium Cyclosilicate (Lokelma)? In this informative video, we will discuss sodium zirconium cyclosilicate, also known as Lokelma, and its potential side effects. Understanding these side effects is important for anyone considering this medication, especially for those managing high blood potassium levels. We will cover common side effects, such as edema and hypokalemia, and how they may impact individuals with heart failure or kidney disease.
Additionally, gastrointestinal symptoms like nausea and decreased appetite will be addressed, along with cardiovascular effects that could arise during treatment. We will also touch on musculoskeletal symptoms and the importance of monitoring them.
Serious side effects, including allergic reactions and respiratory issues, will be highlighted to ensure that viewers are aware of the signs to look for. This knowledge is particularly vital for first responders who may encounter patients experiencing severe reactions in emergency situations.
Always consult with healthcare professionals for personalized medical advice and to discuss any concerns regarding side effects. Staying informed can lead to safer and more effective treatment for patients and first responders alike. Join us for this essential discussion, and subscribe to our channel for more helpful information on first responders medicine.
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#SodiumZirconiumCyclosilicate #Lokelma #PotassiumManagement #MedicationSideEffects #FirstResponders #EmergencyMedicine #PatientCare #HealthAwareness #CardiovascularHealth #GastrointestinalHealth #AllergicReactions #RespiratoryIssues #MuscleCramps #FluidRetention #MedicationSafety
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Please note that all content is for informational purposes only and should not be considered medical advice. Always conduct your own research and consult with professionals when necessary. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.