#Cinnarizine#cyclizine#promethazine#Scopolamine# Granisetron#ondansetron#dolasetron#tropisetron#chlorpromazine#perphenazine#prochlorperazine#trifluoperazine#Metoclopramide#Domperidone#CTZ#nausea#vomiting#motionsickness#vestibulardisorders#Menière’sdisease#morningsicknessofpregnancy#antiemetic The Vomiting center has receptors for
Nurokinin 1 NK-1,
Cannabinoids CB-1,
serotonin 5-HT3,
dopamine D2,
muscarinic M1
and histamine H1 receptors.
The vomiting center can be activated by afferent fibers
arising from the gastrointestinal track,
Chemoreceptor trigger zone CTZ,
Cerebral cortex and vestibular apparatus.
The CTZ or Chemo receptor trigger zone, is located at the end of fourth ventricle.
CTZ have receptor of serotonin 5-HT3, dopamine D2, muscarinic M1 receptors.
It lies outside of blood brain barrier and stimulate vomiting center in response to
blood borne substances including cytotoxic cancer chemotherapy drugs.
The excessive vestibular stimulation in motion sickness activates the vomiting center
via cholinergic and histaminergic nerve fibers that projected through vestibulocerebellar region of cerebellum.
The irritation of gastric mucosa by chemotheraperautic agents, endogenous toxin and poison leads to
secretion of 5-HT which activate 5-HT3 receptor and this stimuli travel from the gastrointestinal tract
via the nucleus tractus solitarius (NTS) to stimulate vomiting center in the medulla.
Emesis by psychological stimuli such as fear, dread, or obnoxious sights and odors is mediated in
cerebral cortex,
this concept is poorly understood yet.
Nurokinin 1 NK-1, Cannabinoids CB-1 and Histamine could be responsible this effect.
Now we will see the site of action of various antiemetic drugs
Antihistaminic
Antihistaminic antiemetic includes
Cinnarizine, cyclizine and promethazine
Antihistaminic drugs blocks muscarinic M1 receptors or histamine H1 receptors or both types of receptors
in the vestibular tracts that project to the vomiting center and in the CTZ.
Antihistaminic drug Cyclizine is used in motion sickness.
cinnarizine is used in motion sickness and vestibular disorders such as Menière’s disease)
promethazine is used in severe morning sickness of pregnancy.

Antimuscarinics
Antimuscarinics drug Scopolamine is used in motion sickness.
It causes blocking of muscarinic M1 in vestibular tracts.

5-HT3 receptors antagonist
5-HT3 receptors antagonist includes Granisetron, ondansetron, dolasetron, tropisetron and palonsetron.
They are particular value in preventing and treating the vomiting and nausea.
commonly encountered postoperatively as well as that caused by radiation therapy or administration of cytotoxic drugs such as cisplatin.
They prevent emesis by competitively blocking 5-HT3

CBS2’s Dr. Max Gomez reports.

East Texas law enforcement cracking down on illegal use of promethazine drug after noticing increase

This video is about that is the Promethazine hydrochloride tablet uses in hindi - Review phenergan tablets 25 mg - Nausea, Vomiting, Motion sickness, Side Effects, Dsoe @health.plusguru
Question and Query
promethazine hydrochloride tablet uses in hindi, promethazine hydrochloride,
promethazine hydrochloride 25mg, promethazine hydrochloride 10mg,
promethazine hydrochloride tablets l.p, promethazine hydrochloride 25mg uses in hindi,
promethazine hydrochloride 25mg uses in urdu, promethazine tablets,
promethazine tablet uses in hindi, promethazine tablet for motion sickness,
promethazine tablet kis kaam aati hai, promethazine tablet uses in tamil,
promethazine tablet in hindi, Phenergan tablets uses in hindi,
phenergan tablets uses, phenergan tablets for sleep, phenergan tablets side effects,
phenergan tablets 25mg night time,
#phenergantablets #health #healthplus #health+

Phenergan | Promethazine HCL | Anti Allergic | Uses | Dose | Side effects | Nausea | Vomiting




Your Queries :



Phenergan Tablet
Anti allergic
Nausea
Vomiting
Oral Solid Tablet
Phenothiazine derivative
Antidopaminergic
Antihistamine
Anticholinergic
Medicine Information
All about Medicines
Medical information
Health professionals
Hospital information
Medical Students
Clinical information
Pharmacist
Doctors
Nurses
Dispenser
World Health Organization
Federal Drug Authority
Health and Safety Guidelines

#health #Pharmacology #medicine #medicalnotes #pharmacists #doctor #Nurses

"Disclaimer: The information provided on this page is for general informational purposes only and should not be considered medical advice. Always consult with a healthcare professional before making any medical decisions or starting any treatments. The content shared here is not intended to diagnose, treat, cure, or prevent any disease. We do not endorse or promote any specific medical products or services. Use the information at your own risk. Please consult a qualified healthcare professional for personalized advice."
🔔 Remember to customize it to fit your specific needs and make sure to consult with a legal professional for any specific requirements.


@Doctor.of.medicine

Promethazine is a prescription medication used to treat a variety of ailments. It’s commonly used as a sedative, antihistamine, and anti-nausea drug, but can also be used to treat motion sickness, insomnia, and anxiety.
While it’s an effective medication, it also carries some risks that must be understood before taking it. In this article, we’ll explore the benefits and risks of Promethazine and what you need to know to make an informed decision about whether it’s right for you.
We’ll also look at how to use it safely and what to watch out for. With the right information, you can make sure Promethazine is a safe and effective choice for your condition.

What is Promethazine?

Promethazine is an antihistamine and sedative drug used to treat allergies, motion sickness, and nausea. It’s also used to induce sleep and treat anxiety.
Promethazine helps block the action of histamine, a substance in the body that causes allergic reactions. It can also block some of the effects of natural chemicals in the body that cause nausea and vomiting.
Promethazine is available in tablet, capsule, liquid, and suppository forms. It’s also available in combination with other medications such as acetaminophen, codeine, and hydrocodone.
Promethazine is available in both prescription and over-the-counter forms.

Benefits of Promethazine

Promethazine is an effective medication for many conditions. It can help reduce allergies, nausea, vomiting, and motion sickness. It can also be used to sedate and induce sleep in people who have difficulty sleeping.
Promethazine can also help reduce anxiety and can be used to help with pain relief when taken in combination with other medications.
Promethazine is generally considered safe when taken as prescribed and monitored by a doctor. It’s important to follow your doctor’s instructions and be aware of the potential side effects and risks.

Common Uses of Promethazine

Promethazine is most commonly used to treat allergies, motion sickness, and nausea. It can also be used to induce sleep and treat anxiety.
It’s also commonly used in combination with other medications such as acetaminophen, codeine, and hydrocodone to treat pain.
Promethazine is also used to treat conditions such as hives, itching, and rashes. It can also be used to reduce the effects of certain drugs that cause nausea and vomiting.

Potential Side Effects of Promethazine

Promethazine is generally considered safe when taken as prescribed and monitored by a doctor. However, it can cause some side effects including drowsiness, dry mouth, dizziness, blurred vision, and constipation.
It can also cause confusion, agitation, and nightmares in some people.
It’s important to talk to your doctor if you experience any of these side effects. Your doctor may recommend reducing the dose or changing the medication.

How to Use Promethazine Safely

It’s important to follow your doctor’s instructions when taking Promethazine. Make sure to read the label carefully and take only the recommended dose.
Do not take more than the recommended dose or take it for longer than recommended by your doctor.
It’s also important to take Promethazine with food or milk to reduce the risk of stomach upset. Do not take it if you have had an allergic reaction to it or any of its ingredients.

Interactions with Other Drugs

Promethazine can interact with some medications. Make sure to tell your doctor about any other medications you are taking, including prescription, over-the-counter, herbal, and supplements.
This will help your doctor determine if Promethazine is safe and effective for you.
Promethazine can also interact with alcohol, making it more likely to cause drowsiness and dizziness.
Avoid driving or operating machinery while taking Promethazine and drinking alcohol.

Risks of Taking Promethazine

Promethazine carries some risks when taken in large doses or for a long period of time. It can cause drowsiness, dizziness, confusion, and agitation.
It can also cause an irregular heartbeat, seizures, and breathing problems.
There are also risks for people with certain medical conditions. People with breathing problems, glaucoma, or asthma should not take Promethazine.

"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.

Phenergan syrup | Promethazine syrup | Promethazine hydrochloride syrup, uses / side effects/ dosage

#phenergansyrup

Time

Topic

00:06 Promethazine syrup introduction.

01:50 Promethazine syrup important information / Warnings.

04:04 Promethazine syrup uses in detail.

05:46 Promethazine syrup side effects.

06:23 Promethazine syrup dosage | dose Promethazine syrup is 1st generation antihistaminic medicine, it is highly sedative medicine. Promethazine syrup is also knows as promethazine hydrochloride syrup or promethazine syrup ip.

The most popular brand name of promethazine hcl syrup is Phenergan syrup.

Phenergan syrup strength is 5mg/5ml and available packing id Phenergan syrup 100ml. Phenargan syrup / Promethazine hydrochloride syrup is contraindicated in the patient who have ever had

1. Asthma 2. COPD 3. Breathing problem 4. Sleep apnea 5. History of seizure 6. Bone marrow depression / weak imunity 7. Glaucoma 8. Enlarge prostate 9. Urination problem 10. Heart disease 11. High BP 12. Liver disease and many other.
Phenargan syrup | Promethazine syrup ip uses to treat

1. Allergic reations

2. Motion sickness

3. Nausea / vomiting

4. Insomina

5. Sleeping disorder And in many other diseases Promethazine syrup | Phenargan syrup side

effects 1 Drowsiness / dizziness 2. Dry mouth 3.

Respiratory depression 4. Blurred vision 5. Dry nasal passage 6. Constipation 7. Frequent urination 8. Sleeping 9. confusion in elderly patient with many other.

We also discuss about promethazine syrup / Phenargan syrup Phenargan syrup strength / Contraindication /

Use in detail / Dosage / Side effects and many

more in hindi.

Related topic covered

1. what is Phenergan used for?

2. How much Phenergan can you give a child?

3. What is in Phenergan cough syrup?

4. Is Phenergan good for sleep?

5. Promethazine hydrochloride syrup uses in hindi.

6. promethazine syrup Phenergan in hindi

Like, share, subscribe

#mohitdadich #phenargan

#promethazin

#promethazinesyrup

#phenergansyrup

Promethazine Syrup (Phenergan syrup) is used to relieve cough, runny or stuffy nose, sneezing, or other symptoms caused by allergies or the common cold.

Video Content:
0:00 Promethazine Syrup
0:37 How to use
1:49 Contraindications
2:08 Precautions
2:51 Side Effects

Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor.

#Promethazine #Phenergan #medicine

00:06 Promethazine injection introduction & What is in video
01:15 Promethazine injection strength / route
01:58 Promethazine injection contraindication
03:03 Promethazine injection uses
04:40 Promethazine injection dosage / how to inject
06:47 Promethazine injection side effects

Promethazine is a first generation antihistaminic medicine. it is highly sedative and belongs to Phenothazine class.
Promethazine injection is also names as promethazine hcl injection.
Promethazine injection is available in 25mg/ml and 50mg/ml of strength.
Promethazine injection popular brand name is Phenargan injection.
Phenargan injection / Promethazine injection can be injected from both I.V and I.M. route.

Phenargan injestion / Promethazine is contraindicated in the patient who have ever had
1. Asthma
2. COPD
3. Breathing problem
4. Sleep apnea
5. History of seizure
6. Bone marrow depression / weak imunity
7. Glaucoma
8. Enlarge prostate
9. Urination problem
10. Heart disease
11. High BP
12. Liver disease and many other

Phenargan injection | Promethazine injection uses to treat

1. Nausea induced by anaesthetic medication.
2. Post-operative Nausea.
3. Morning sickness
4. Radiation sickness
5. Nausea during pregnancy
6. Allergic reaction include hay fever, anaphylaxis.
7. And in many other diseases
Promethazine injection | Phenargan injection side effects

1. Drowsiness / dizziness
2. Dry mouth
3. Respiratory depression
4. Blurred vision
5. dry nasal passage
6. constipation
7. frequent urination
8. sleeping
9. confusion in elderly patient with many other

We also discuss about promethazine injection / Phenargan injection
Phenargan injection strength
Route of administration
Contraindication
Use in detail
Dosage
Side effects and many more in hindi.

Like, share, subscribe

LEARN ABOUT MEDICINE

#learnaboutmedicine
#mohitdadich
#phenargan
#promethazin
#promethazinInjection

PROMETHAZINE, promethazine hydrochloride, promethazine hcl.
Brand names of Promethazine generic: Phenergan, Remsed, Phenadoz, Promethazine DM, Promethegan.
Promethazine tablets: promethazine 25 mg, promethazine 50 mg.

Promethazine review: what is promethazine?, what is promethazine used for?, promethazine side effects, promethazine uses, promethazine dosage.

Why is this medication prescribed?

Promethazine is used to relieve the symptoms of allergic reactions such as allergic rhinitis (runny nose and watery eyes caused by allergy to pollen, mold or dust), allergic conjunctivitis (red, watery eyes caused by allergies), allergic skin reactions, and allergic reactions to blood or plasma products.

Promethazine is used with other medications to treat anaphylaxis (sudden, severe allergic reactions) and the symptoms of the common cold such as sneezing, cough, and runny nose.
Promethazine is also used to relax and sedate patients before and after surgery, during labor, and at other times.
Promethazine is also used to prevent and control nausea and vomiting that may occur after surgery, and with other medications to help relieve pain after surgery.
Promethazine is also used to prevent and treat motion sickness.
Promethazine helps control symptoms, but will not treat the cause of the symptoms or speed recovery.
Promethazine is in a class of medications called phenothiazines. It works by blocking the action of a certain natural substance in the body.


How should this medicine be used?

Promethazine comes as a tablet and syrup (liquid) to take by mouth and as a suppository to use rectally.
When promethazine is used to treat allergies, it is usually taken one to four times daily, before meals or at bedtime.
When promethazine is used to relieve cold symptoms, it is usually taken every 4 to 6 hours as needed.
When promethazine is used to treat or prevent nausea and vomiting it is usually taken every 4 to 6 hours as needed.
Promethazine may also be taken at bedtime the night before surgery to relieve anxiety and produce quiet sleep.

Promethazine suppositories are for rectal use only. Do not try to swallow the suppositories or insert in any other part of your body.

If you are taking promethazine liquid, do not use a household spoon to measure your dose.
Use the measuring spoon or cup that came with the medication or use a spoon made especially for measuring medication.


What special precautions should I follow?

Before taking promethazine:

tell your doctor and pharmacist if you are allergic to promethazine, other phenothiazines (certain medications used to treat mental illness, nausea, vomiting, severe hiccups, and other conditions) or any other medications. Also tell your doctor and pharmacist if you have ever had an unusual or unexpected reaction when you took promethazine, another phenothiazine, or any other medication. Ask your doctor or pharmacist if you do not know if a medication you are allergic to is a phenothiazine.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements and herbal products you are taking or plan to take.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.
If you become pregnant while taking promethazine, call your doctor.
talk to your doctor about the risks and benefits of taking promethazine if you are 65 years of age or older. Older adults should not usually take promethazine because it is not as safe as other medications that can be used to treat the same conditions.

if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking promethazine.

you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
If you are giving promethazine to a child, watch the child to be sure he or she does not get hurt while riding a bike or participating in other activities that could be dangerous.

ask your doctor about the safe use of alcohol while you are taking this medication.
Alcohol can make the side effects of promethazine worse.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen.
Promethazine may make your skin sensitive to sunlight.


What side effects can this medication cause?

Promethazine can cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

dry mouth.
drowsiness.
listlessness.
difficulty falling asleep or staying asleep.
nightmares.
dizziness.
ringing in ears.
blurred or double vision.
loss of coordination.
nausea.
vomiting.
nervousness.
restlessness.
hyperactivity.
abnormally happy mood.
stuffy nose.
itching.

Time Topic
00:06 Promethazine syrup introduction.
01:50 Promethazine syrup important information / Warnings.
04:04 Promethazine syrup uses in detail.
05:46 Promethazine syrup side effects.
06:23 Promethazine syrup dosage | dose
Promethazine syrup is 1st generation antihistaminic medicine, it is highly sedative medicine. Promethazine syrup is also knows as promethazine hydrochloride syrup or promethazine syrup ip.
The most popular brand name of promethazine hcl syrup is Phenergan syrup.
Phenergan syrup strength is 5mg/5ml and available packing id Phenergan syrup 100ml.
Phenargan syrup / Promethazine hydrochloride syrup is contraindicated in the patient who have ever had
1. Asthma 2. COPD 3. Breathing problem 4. Sleep apnea 5. History of seizure 6. Bone marrow depression / weak imunity 7. Glaucoma 8. Enlarge prostate 9. Urination problem 10. Heart disease 11. High BP 12. Liver disease and many other.
Phenargan syrup | Promethazine syrup ip uses to treat
1. Allergic reations
2. Motion sickness
3. Nausea / vomiting
4. Insomina
5. Sleeping disorder And in many other diseases
Promethazine syrup | Phenargan syrup side effects
1 Drowsiness / dizziness 2. Dry mouth 3. Respiratory depression 4. Blurred vision 5. Dry nasal passage 6. Constipation 7. Frequent urination 8. Sleeping 9. confusion in elderly patient with many other.
We also discuss about promethazine syrup / Phenargan syrup
Phenargan syrup strength / Contraindication / Use in detail / Dosage / Side effects and many more in hindi.
Related topic covered
1. what is Phenergan used for?
2. How much Phenergan can you give a child?
3. What is in Phenergan cough syrup?
4. Is Phenergan good for sleep?
5. Promethazine hydrochloride syrup uses in hindi.
6. promethazine syrup Phenergan in hindi
Like, share, subscribe
LEARN ABOUT MEDICINE
#learnaboutmedicine
#mohitdadich
#phenargan
#promethazin
#promethazinesyrup
#phenergansyrup

Clinical Cousins cover Promethazine (Phenergan) in their effective and concise "Minute to Master" series.

Promethazine

in this video, I have explained in detail about usage , dosage , and side effects profile of phenergan syrup for children.
#phenergan #kidssleep #babycare #sleep #motherhood #drarshadchildspecialist

Promethazine is a phenothiazine derivative indicated for prevention of nausea and vomiting.

Welcome to Medication Minute, where we provide quick, essential overviews of critical EMS drugs. In this episode, we cover Promethazine (Phenergan), a powerful antiemetic and antihistamine. Learn how to use Phenergan effectively to manage nausea and vomiting, especially when paired with pain medications like morphine. We’ll also highlight important precautions to prevent complications during IV administration.

🔑 Topics Covered:

What is Phenergan?
Indications for nausea and vomiting
Proper adult dosing: 25 mg IV
Critical safety tips: Avoiding tissue necrosis and managing burning sensation
Precautions for co-administration with pain medications
⏱ Quick Facts:

Potentiates sedation when combined with opioids
Requires dilution and slow IV administration to avoid complications
Essential for managing nausea in prehospital settings
Stay informed and ensure safe administration practices in emergency care. 🚑

📢 Subscribe for more practical medication insights tailored for EMS and healthcare professionals.