Hi Friends, welcome to the Dr Binocs show.
In this video, Dr Binocs will explain, "What Causes Diabetes?".

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Pharmacist review of the side effects of Trulicity as well as some precautions and counseling tips to take into account if you are prescribed Trulicity (Dulaglutide)

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Watch Full Podcast Here: https://youtu.be/UqeowmwMgFk
In this episode, Jillian sits with Heather Heying, Ph.D., to explore the vaccine debate, the Project Stargate / mRNA role in cancer research, lab leak theory, and the ethics of high-risk gain of function research. Plus, RFK Jr.'s controversial appointment and its impact on health policy, This balanced, in-depth conversation encourages critical thinking and open exploration of complex scientific issues.

Ozempic (semaglutide) is an injectable GLP-1 agonist that helps treat Type 2 diabetes. If you haven’t been able to control blood sugar with other medications, Ozempic may be a good option.

Save on this medication: https://goodrx.co/OzempicCoupon
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This news is important to those who are diabetic and develop hypoglycemia as a complication of antidiabetic treatment.

Before moving to further information, If you learn something or if you find information provided in this video as help full, please motivate us by subscribing, liking and sharing this video.

Severe hypoglycemia occurs when a patient’s blood sugar levels fall to a level where he or she becomes confused or unconscious or suffers from other symptoms that require assistance from another person to treat.

Typically, severe hypoglycemia occurs in people with diabetes who are using insulin treatment.

Glucagon increases blood sugar levels in the body by stimulating the liver to release stored glucose into the bloodstream.
It has the opposite effect of insulin, which lowers blood sugar levels.

Until now, people suffering from a severe hypoglycemic episode had to be treated with a glucagon injection that first had to be mixed in a several-step process.

Injectable glucagon has been approved for use in the U.S. for several decades.

The U.S. Food and Drug Administration on 24 July 2019 approved Eli Lilly and Company’s, Baqsimi nasal powder, the first glucagon therapy approved for the emergency treatment of severe hypoglycemia that can be administered without an injection.
Baqsimi is approved to treat severe hypoglycemia in patients with diabetes ages four and older.

This new way to administer glucagon may simplify the process, which can be critical during an episode and simplify the treatment.
Baqsimi is a powder administered into the nose.

It will come in a single-use dispenser that can be given to someone suffering from a severe hypoglycemic episode.

Thank You for watching this video.

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Check out my other videos:

SGLT2 inhibitors: Do you know about this new diabetes medications? https://youtu.be/EtNM0dX36c8

New class of Oral diabetes drugs: DPP-4 Inhibitors / Gliptins: https://youtu.be/aSo9E0INpvM

Side effects of steroids: https://youtu.be/iEagfQUQs8E
6 MAJOR LONG TERM COMPLICATIONS OF DIABETES: https://youtu.be/6Yfrr9L6tCk

Adalimumab (Humira/ Amgevita/ Imraldi/ Hyrimoz/ Hulio) -A magical drug for autoimmune diseases: https://youtu.be/vQvYfsdqDmg

Vyleesi (bremelanotide)- New Female Version of Viagra approved by FDA: https://youtu.be/WtrITfPP7B8

FDA Warnings: Grapefruit Juice and Some Drugs Don't Mix: https://youtu.be/VfoDzGQaStY

Orilissa / Elagolix: FDA approved New drug for endometriosis: https://youtu.be/LU_RO8GokOI

FDA approved new drug SKYRIZI (risankizumab) for Plaque Psoriasis: an interleukin-23 inhibitor: https://youtu.be/Z_Llu_njpXc

Pharma, life science and medical news Jul 2019: https://youtu.be/UPl-jNilWvw

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Dr. Bikman’s Metabolic Classroom lecture this week explores the physiological role and implications of GLP-1 (glucagon-like peptide-1) and the GLP-1 receptor agonist drugs used for type 2 diabetes management and weight loss.

Ben begins by explaining GLP-1 as a hormone produced in the intestines in response to food. It plays a vital role in slowing gastric emptying, suppressing glucagon, and regulating appetite by signaling fullness to the brain. These mechanisms contribute to its effects on stabilizing blood sugar and enhancing insulin sensitivity.

He then delves into GLP-1 receptor agonists, drugs that mimic GLP-1’s actions, including semaglutide, liraglutide, and others marketed under brand names like Ozempic and Wegovy. These medications have gained fame for their weight loss efficacy, often leading to reductions in body weight by 15% or more.

However, Ben emphasizes that weight loss involves not only fat but also lean mass, raising concerns about muscle loss and metabolic health. Additionally, he discusses the medications’ side effects, including depression, anhedonia, and potential long-term complications like fat cell development and gallstones.

The lecture also addresses the diminishing returns of these drugs over time, noting that their efficacy in reducing cravings and improving eating control tends to wane after prolonged use. Dr. Bikman highlights that education on healthy eating and resistance training is crucial for maintaining health outcomes, as reliance solely on medication can lead to unintended consequences, such as increased fat regain after discontinuation.

Ben concludes by stressing the importance of combining these drugs with a low-carb diet and resistance training to minimize muscle loss and optimize long-term outcomes. He encourages using the lowest effective dose and underscores the need for lifestyle changes to complement pharmacological interventions.

Show Notes/References:
For complete show notes and references referred to in this episode, we invite you to become a Ben Bikman Insider subscriber. As a subscriber, you’ll enjoy real-time, livestream Metabolic Classroom access which includes live Q&A with Ben, ad-free Metabolic Classroom Podcast episodes, show notes and references, Ben’s Research Reviews Podcast, and a searchable archive that includes all Metabolic Classroom episodes and Research Reviews. Learn more about becoming an Insider on our website: https://www.benbikman.com

(Auto-Translate Note: You can click the gear icon at the bottom of this video to auto-translate captions. For example, to translate into Polish, select Subtitles, choose Auto-Translate, then first choose English, then choose Auto-Translate again, then choose Polish.)

#GLP1 #WeightLossDrugs #Ozempic #Wegovy #Semaglutide #Liraglutide #Type2Diabetes #DiabetesManagement #InsulinResistance #WeightLossTips #MetabolicHealth #DrBenBikman #MetabolicScience #MuscleHealth #MentalHealthMatters #LowCarbDiet #FatLoss #HealthRisks #DiabetesDrugs #ScienceExplained

Timestamps:
00:01 - Introduction and Overview
02:16 - What is GLP-1?
03:15 - GLP-1's Role in Metabolism
05:08 - Appetite Regulation and Insulin Effects
07:05 - GLP-1 and Blood Sugar Management
08:10 - Introduction to GLP-1 Receptor Agonists
09:05 - Key GLP-1 Drugs and Brand Names
12:04 - Weight Loss Mechanisms of GLP-1 Drugs
14:06 - Mental Health Risks of GLP-1 Drugs
16:15 - Muscle Loss Concerns
18:24 - Fat Cell Differentiation and Regain Risk
20:07 - Long-Term Diminishing Effects
25:30 - Pancreatitis and Gallstones
29:11 - Closing Thoughts and Recommendations

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What Is Glucagon Roles Side Effects And How It Works With Insulin

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There is some misrepresentation of images in some of my videos. The reason has been that, there are some images and words that YouTube doesn't accept to be uploaded. To comply with the YouTube community guidelines.

Disclaimer

All advice in these videos are to be taken with caution. Please visit your nearby hospital for any health-related issues you may be facing.
Thanks.

Credit to the creator of the images on this video.
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#diabetes #healthpioneers

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Chapters:
00:00 Intro
00:18 Miracle weight-loss drugs
00:49 How these drugs work?
02:26 Industry response
03:01 Problem 1: Exacerbating nutritional deficiencies
03:45 Problem 2: Muscle loss
04:48 Problem 3: These drugs are expensive
05:02 Problem 4: Side-effects
05:57 Problem 5: Regaining the lost weight
06:53 Similarity to anabolic steroids
08:01 Conclusion

Reference:
https://pubmed.ncbi.nlm.nih.gov/38029929/
https://www.frontiersin.org/jo....urnals/pharmacology/
https://www.bmj.com/content/384/bmj-2023-076410

#ozempic #wegovy #rybelsus #semaglutide #weightlossdrugs #nutrition #weightloss #steroids #dieting #healthwarnings #mennohenselmans #personaltrainer #personaltrainers #personaltraining #personaltrainerlife #personaltraineronline

GLP-1 (glucagon-like peptide 1) receptor agonist (semaglutide, Ozempic, Rybelsus, Wegovy) not only produce weight loss but also improve other metabolic variables, such as blood sugar, blood pressure, and lipids. Here, Dr. Rajnish Mago reviews how you might utilize GLP-1 receptor agonist to help manage antipsychotic-induced metabolic side effects.

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Ever wonder about medicines like Trulicity, Ozempic, or Victoza? These diabetes medications all work in a similar way in the management of Type 2 Diabetes and improving A1c. In this video, I discuss the natural role of GLP-1 in managing blood glucose, how these medications fit into that role, what the benefits are, and what the side effects are.

A couple corrections to the video:
At 1:52, I misspoke and said "glycogen" instead of "glucagon"
At 2:33, I accidentally said "insulin" instead of "intestine".
Sorry about any confusion.

As promised in the video, here are links to relevant studies on the cardiovascular safety/potential benefits of these medications:
Adlyxin: https://www.nejm.org/doi/full/....10.1056/NEJMoa150922
Bydureon: https://www.nejm.org/doi/full/....10.1056/NEJMoa161291
Victoza: https://www.nejm.org/doi/full/....10.1056/NEJMoa160382
Trulicity: https://www.thelancet.com/jour....nals/lancet/article/
Ozempic: https://www.nejm.org/doi/full/....10.1056/NEJMoa160714
Rybelsus: https://www.nejm.org/doi/full/....10.1056/NEJMoa190111

Which GLP-1 agonist is strongest? Let’s compare all the common GLP-1 agonists (Wegovy vs Ozempic vs Rybelsus vs Saxenda vs Victoza vs Trulicity vs Byetta vs Bydureon vs Adlyxin vs Tanzeum) for weight loss. Find out which option may be right for you!

For more information about this topic: https://brianyeungnd.com/2022/....03/24/comparing-glp-
Get EXCLUSIVE content and SUPPORT us: https://ko-fi.com/brianyeungnd

0:00 Intro
0:42 What are GLP-1 agonists?
2:53 Names, uses, and dosing comparisons
5:03 Side effect comparisons
6:36 Availability and cost comparisons
7:23 Weight loss comparisons
8:44 Summary

****************

Learn more about:

Dr. Brian Yeung, ND: https://brianyeungnd.com/about/

****************

DISCLAIMERS

Affiliate links: Please keep in mind that we may receive a commission when you click on our links and make a purchase. This, however, has no bearing on our reviews and comparisons.

Content: All statements made are opinions and not stated as fact. While Dr. Brian and his team makes every effort to fact check the information presented, mistakes can still be made. Dr. Brian and his team are not responsible for any errors or omissions in the information provided. The intent of this channel is not to malign or harm the reputation of any individual, company, or organization. All criticisms are made in good faith and with the aim of providing constructive feedback.

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Medical: Dr. Brian Yeung, ND received his Doctor of Naturopathic Medicine degree from the Canadian College of Naturopathic Medicine in 2013. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Yeung is currently a practicing Naturopathic Doctor with additional prescribing authority and IV therapy certification in Ontario. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Yeung and you. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. BrianYeungND and Dr. Brian Yeung, ND are not liable or responsible for any advice, course of treatment, diagnosis or any conclusions drawn, services or product you obtain through this video or site.

A complete description of Glucagon benefits, dosage form, Indications, antidote effects.indications (In hypoglycemia if sugar can’t be given by mouth, glucagon can be given by injection
Glucagon may be issued to the close relatives of insulin-treated pt. for emergency use in hypoglycemic attack ), dose, administration, precautions, contraindications, overdose, toxicity symptoms, side effects, storage condition, mechanism, indications, and ADR's.


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Cathy covers the mode of action, side effects, and key points of the following oral antidiabetic drug classes and medications: Thiazolidinediones (pioglitazone) and Alpha Glucose Inhbitors (acarbose). The glycogenolytic agent glucagon.

Our Pharmacology video tutorial series is taught by Cathy Parkes BSN, RN, CWCN, PHN and intended to help RN and PN nursing students study for their nursing school exams, including the ATI, HESI and NCLEX.

#NCLEX #pharmacology #endocrine #HESI #Kaplan #ATI #NursingSchool #NursingStudent⁠ #Nurse #RN #PN #Education #LVN #LPN #antidiabetic

0:00 What to Expect?
0:40 Thiazolidinediones
1:01 Side Effects
2:09 Alpha Glucose Inhibitors
2:24 Side Effects
3:15 Glycogenolytic Agent
4:25 Quiz Time!
4:26 Bloopers

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#medicalknowledgeonline
Glucagon is a hormone and emergency medication used to treat severe hypoglycemia by stimulating the liver to release glucose into the bloodstream. It is available in injectable and nasal forms and may cause side effects like nausea, vomiting, and allergic reactions.
*************************
Contents :
1. Generic Name, Drug class, Brande Name, 0:14
2. What is?, 0:43
3. Mechanism of Action 1:02
4. indication , 1:41
5. contraindication 2:03
6. Before taking this medicine (Precautions ), 2:21
7. How to use , 2:54
8. Dosing information, 3:27
9. Miss a dose, Overdose , 3:54
10. Stop or Avoid Taking , 4:12
11. Side Effects, 4:30
12. vital information , 4:55
13. Other Drugs Will Affect 5:19
#medicalknowledgeonline ,
- Generic Name, Drug class, Brande Name ,Precautions , How to use, Side Effects
-----------------------------------------------------------
Content Disclaimer
"This video provides educational content for informational purposes only and is not a substitute for medical advice, diagnosis, or treatment. Always consult your healthcare provider with any questions regarding a medical condition or treatment. We do not endorse any specific treatments, medications, or products discussed on this channel."
********************************************************************
TOPICS
1. ANATOMY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
2. PHYSIOLOGY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
3. DISEASES – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
4. PUBLIC HEALTH- Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
5. Rx – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
6. LABORATORY TEST – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
7. MEDICAL IMAGING – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
8. SURGICAL AND MEDICAL PROCEDURES – topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
9. MICROBIOLOGY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
10. BIOCHEMISTRY – Topics
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11. NUTRITION – Topics
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12. HEALTH TOPICS
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13. MEDICAL & SURGICAL – Topics
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14. PAEDIATRICS / CHILD HEALTH – Topics
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15. MENTAL HEALTH – Topics
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16. MATERNAL HEALTH – Topics
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17. COMMUNITY HEALTH – Topics
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18. NURSING FOUNDATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
19. BIOSTATISTICS – Topics
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20. PATHOLOGY – TOPICS
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21. NURSING EDUCATION – Topics
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22. HOSPITAL MANAGEMENT AND HEALTH CARE ADMINISTRATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
23. NURSING RESEARCH – TOPICS
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24. NURSING FOUNDATION – Topics
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25. PHARMACOLOGY – TOPICS
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26. PUBLIC HEALTH – Topics
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27. INTERNATIONAL DAYS
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28. NURSING - TOPICS
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#medicalknowledgeonline

BETA BLOCKERS OVERDOSE/TOXICITY EMERGENCY TREATMENT WITH GLUCAGON, TOXICOLOGY LECTURES USMLE
In this video on beta blocker overdose I have talked in detail about mechanism treatment and management of beta blocker overdose in emergency department. This video focuses on signs and symptoms toxicity of betablocker effects on body and how to administer glucagon in beta blocker overdose.

CHAPTERS:
(0:00) INTRO
(0:17) Mechanism of Overdose
(0:52) Signs & Symptoms
(1:45) ECG Changes
(2:15) Treatment
(4:34) How to give Glucagon
(6:13) Summary


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What Are The Side Effects Of Glucagon? In this informative video, we will discuss the side effects of glucagon, a medication that plays a key role in treating severe hypoglycemia. Understanding the potential reactions to glucagon is important for healthcare professionals and first responders who may encounter this medication in emergency situations. We will cover both common and serious side effects, shedding light on how they may impact patient care.

Our discussion will include common reactions such as nausea, vomiting, and swelling at the injection site. We'll also highlight more serious concerns, including allergic reactions and their symptoms, as well as the implications for patients with specific health conditions. Monitoring patients after glucagon administration is essential, and we will provide guidance on what to watch for during treatment.

Whether you are a first responder or someone interested in emergency medicine, this video will equip you with the knowledge needed to ensure patient safety when glucagon is administered. Join us as we dive into the important aspects of glucagon side effects and subscribe to our channel for more helpful information on first responders' medicine.

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In this episode, Ana Reisdorf and Michelle Routhenstein discuss the critical relationship between GLP-1 medications and heart health. Michelle, a cardiovascular dietitian, shares insights on the prevention of heart disease, the importance of nutrition, and how GLP-1s can play a role in managing cardiovascular risks.

We explore the significance of understanding personal health metrics, the impact of diet on heart and gut health, and the necessity of maintaining nutrient adequacy, especially for those on GLP-1s. The conversation emphasizes the need for a holistic approach to heart health, integrating medication, nutrition, and lifestyle changes.

About Michelle:

Michelle Routhenstein, MS, RD, CDCES, CDN is a leading cardiovascular dietitian specializing in preventive cardiology nutrition. With over a decade of experience, she helps individuals manage and prevent heart disease and its complications through a science-based, nutrient-sufficient diet and sustainable lifestyle strategies.

Michelle’s expertise focuses on reducing the risk of heart attacks, strokes, and heart failure by improving blood flow, supporting optimal cardiovascular function, and addressing key risk factors. Her personalized, whole-person approach empowers clients to optimize lab results, correct nutrient imbalances, and slow or reverse disease progression.

Through compassionate, data-driven care, Michelle equips individuals with the tools to build lasting heart health.
Learn more at www.entirelynourished.com.

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0:00 - Introduction
1:40 - All Topics Covered
2:36 - Mechanisms of Action
24:07 - GLP1A on Health Markers
24:15 - Study 223
27:47 - Body Weight [and how to read the data]
35:37 - Heart Rate
36:35 - Blood Pressure
37:08 - Low Density Lipoproteins (LDL-Cholesterol)
38:48 - Glycated Hemoglobin (HbA1C)
45:03 - GLP1A on Mortality
45:20 - Mortality
49:09 - Side Effects
52:46 - Mid-Point Conclusions/Take Aways

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Glucagon

Generic Name: glucagon

Trade Name: GlucaGen

Indication: severe hypoglycemia, antidote for beta blockers and calcium channel blockers

Action: stimulates production of glucose from stores, relaxes GI tract

Therapeutic Class: hormones

Pharmacologic Class: pancreatics

Nursing Considerations
 may cause anaphylaxis
 may cause hypotension
 assess for signs of hypoglycemia, neuro status
 monitor serum glucose levels
 teach patient signs of hypoglycemia