Every year up to 30 thousand Americans are diagnosed with Crohn's disease. It's an inflammatory condition of the intestines that causes pain, cramping and constant diarrhea. There is no cure for Crohn's disease, but treatment keeps getting better. More on a new generation of medications from Mayo Clinic.

TREMFYA loading dose Week 0 injection. Let me know your thoughts on the comments and thanks for watching! good luck if you're starting this one!

** I didn't mention in the video but it is very important not to stop the injection midway or else the pen will lock and you won't get the full dose.

**Also, this pen is different from other auto injector pens in that as you push down, the medication will empty. So you can actually control the speed of your shot. I just want to emphasize how important it is to not lift up the pen at all once you've started or else the shot will be wasted. Anyways Good luck to you!

Tremfya is FDA approved for the treatment of psoriatic arthritis and plaque psoriasis. Let's learn how to inject Tremfya at home.

General information regarding Tremfya (guselkumab). Content created leveraging AI with the goal of bridging access across communities. Please flag any suggestions or errors in the comment section. Thank you!

TREMFYA® is indicated for the treatment of adults with moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

In this video, we explore Tremfya (guselkumab), a groundbreaking treatment approved by the FDA for moderate-to-severe plaque psoriasis and active psoriatic arthritis. Discover how Tremfya works, its administration guidelines, and the results of pivotal studies like ORION and DISCOVER-1/2. Learn about its benefits, potential side effects, and important precautions, including tuberculosis screening and immunization requirements. If you or someone you know suffers from these conditions, this video provides crucial information on how Tremfya could improve quality of life.

Warning: The information provided in this video is for educational and informational purposes only and is not intended as medical advice. It is not a substitute for professional medical diagnosis, treatment, or advice. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have learned from this video or any linked materials.

#saroarakelians #tremfya #guselkumab #plaque #plaquepsoriasis #psoriasis #janssen

There has been some speculation on whether or not biologic medications can increase a patient's risk of getting cancer in the long run. Dr. Laura Cappelli from the Arthritis Center discusses these risks as well as the research studies behind them.

12 months after my first shot. Clear skin for the last 11 months. Very happy with this medication and with my results!

New approaches to moderate to severe psoriasis unburden even the most stubborn cases.  This progression stems from recent understanding of the disease as an immune abnormality leading to chronic skin inflammation.  Over the past decade “biologics” have supplanted topical steroids and tar ointments when the disease covers more than 10% of the skin’s surface.
 
Early biologics including Humira, Enbrel and Remicade offer moderate relief but targeted a wider swath of the immune system.  Newer drugs narrow their focus and offer a greater likelihood of complete skin clearance within a relatively short timeframe.  Among the new generation are Cosentyx, Taltz and now Tremfya.
 
Tremfya is the first drug to specifically attack a critical messenger in the inflammatory cascade.  It blocks the ability of IL-23 to initiate the process leading to the psoriatic  manifestations of redness, itching and skin discomfort.
 
Treatment may be administered by either the patient or health care practitioner.  After an initial subcutaneous injection and another 1 month later, therapy continues with a single shot every 8 weeks.
 
First the good news – after 16 weeks, about 85% of patients initially suffering moderate to severe disease can expect clear or almost completely clear skin.  The bad news – the cash price for the drug is well is excess of $10,000.00 a syringe or $60,000.00 each year.  For those paying full price this averages $225 every day.
 

Fortunately the drug company whose sales exceed $200,000,000.00 each day are kind enough to offer a copay card that limits your out of pocket cost to $5 per syringe.  They seem content to reap their rewards from the insurance companies who in turn raise their premiums on everyone to cover these inflated charges.

I’ve been dealing with certain side effects or what I believe are side effects for quite some time while taking tremfya please look into If you yourself are going to use it.

Welcome to a comprehensive exploration of Tremfya, a revolutionary medication transforming the treatment landscape for psoriasis. In this guide, we will delve into various aspects of Tremfya, including its uses, mechanism of action, potential side effects, and the hope it brings to individuals battling psoriasis.

Tremfya: A Breakthrough in Psoriasis Treatment

Tremfya, also known as guselkumab, stands at the forefront of advancements in treating moderate to severe plaque psoriasis. It is a monoclonal antibody designed to specifically target a protein in the body believed to play a crucial role in psoriasis development.

Understanding Its Uses

Plaque Psoriasis Treatment:
Tremfya is primarily prescribed for the treatment of moderate to severe plaque psoriasis in adults. Plaque psoriasis is a chronic skin condition characterized by raised, red, and scaly patches on the skin. Tremfya has demonstrated exceptional efficacy in providing significant relief to individuals suffering from this debilitating condition.
Mechanism of Action: How Tremfya Works

Tremfya works by blocking a protein called interleukin-23 (IL-23), which is believed to play a critical role in the development of psoriasis. By inhibiting IL-23, Tremfya helps to suppress the immune response that contributes to the characteristic symptoms of psoriasis, leading to a reduction in skin lesions and improved skin condition.

Balancing Benefits and Risks: Tremfya Side Effects

Common Side Effects:
Common side effects of Tremfya may include upper respiratory infections, headache, tiredness, injection site reactions, and diarrhea. These side effects are generally mild and temporary, often subsiding with continued use.

Serious Side Effects:
While rare, some individuals may experience more severe side effects such as serious infections, allergic reactions, or worsening of pre-existing conditions. It is essential to promptly report any unusual symptoms or reactions to a healthcare professional.

Patient Perspectives: Tremfya Reviews

Sarah's Journey: Reclaiming Confidence with Tremfya
Sarah, who has struggled with psoriasis for years, shares her transformative experience with Tremfya. She discusses how the medication has not only cleared her skin but also restored her confidence and improved her overall quality of life.

Michael's Story: A New Lease on Life with Tremfya
Michael, diagnosed with severe plaque psoriasis, talks about how Tremfya became a game-changer in his psoriasis treatment. He narrates how the consistent use of Tremfya has significantly reduced the frequency and intensity of psoriasis flare-ups.

Conclusion: Tremfya Pioneering Psoriasis Treatment

In conclusion, Tremfya represents a breakthrough in the treatment of moderate to severe plaque psoriasis, offering renewed hope to individuals grappling with this challenging condition. Understanding its uses, mechanism of action, potential side effects, and the experiences of those who have benefited from it empowers both healthcare providers and patients to make informed decisions regarding its usage, ultimately contributing to a better quality of life for those battling psoriasis.

Thank you.
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"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.



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