Ivermectin Side Effects

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Ivermectin & Cancer: Hype vs. Science—What’s the Reality? Side Effects 1 Views • 24 days ago

Ivermectin, widely known as an antiparasitic medication, has been investigated for its potential anticancer properties in preclinical studies. Researchers have explored its effects on various cancer cell lines and its possible mechanisms of action.
In this episode, Dr. Moss weighs in on this controversial topic, and let's us know where he feels the scientific research stands, and what the implications of the research mean for the future of cancer treatment.

Cited Studies and Research Links
1. Award of Nobel Prize to discoverers of ivermectin: Nobel Prize Committee. Nobel Prize in Physiology or Medicine 2015, October 5, 2015. https://www.nobelprize.org/pri....zes/medicine/2015/pr

2. "Among adults with mild COVID-19, a 5-day course of ivermectin, compared with placebo, did not significantly improve the time to resolution of symptoms.” (Ahmed 2021)
-- Ahmed S, Karim MM, Ross AG, et al. A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness. Int J Infect Dis. 2021 Feb;103:214-216. doi: 10.1016/j.ijid.2020.11.191. Epub 2020 Dec 2. PMID: 33278625; PMCID: PMC7709596.
https://pubmed.ncbi.nlm.nih.gov/33278625/

3. Naggie S, Boulware DR, Lindsell CJ, et al. Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19: A Randomized Clinical Trial. JAMA. 2023 Mar 21;329(11):888-897. doi: 10.1001/jama.2023.1650. Erratum in: JAMA. 2024 Jun 4;331(21):1867. doi: 10.1001/jama.2024.8712. Erratum in: JAMA. 2024 Jun 4;331(21):1866-1867. doi: 10.1001/jama.2024.8723. PMID: 36807465; PMCID: PMC9941969.
https://pubmed.ncbi.nlm.nih.gov/36807465/

4. ‘Recently, ivermectin has been reported to inhibit the proliferation of several tumor cells by regulating multiple signaling pathways. This suggests that ivermectin may be an anticancer drug with great potential" (Tang 2021).
--Tang M, Hu X, Wang Y, et al. Ivermectin, a potential anticancer drug derived from an antiparasitic drug. Pharmacol Res. 2021 Jan;163:105207. doi: 10.1016/j.phrs.2020.105207. Epub 2020 Sep 21. PMID: 32971268; PMCID: PMC7505114.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7505114/

5. "Ivermectin preferentially inhibited cancer stem‑like cells (CSC) in breast cancer cells and downregulated the expression of 'stemness' genes" (Dominguez-Gomez 2018).
--Dominguez-Gomez G., Chavez-Blanco A., Medina-Franco J.L., et al. Ivermectin as an inhibitor of cancer stem-like cells. Mol Med Rep. 2018;17(2):3397–3403. doi: 10.3892/mmr.2017.8231.
https://pubmed.ncbi.nlm.nih.gov/29257278/

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Assistant Secretary for Health.
Phone: 202-690-7694.
Email: [email protected].
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Media Inquiries: [email protected] and 202-205-0143.

Considerations & Limitations
• Most research is preclinical, meaning studies have been done in cells and animal models, but not yet proven in large human trials.
• Potential side effects: Though generally safe at prescribed doses, ivermectin is not an FDA-approved cancer treatment, and its effects in cancer patients require further study.

While early studies indicate that ivermectin has potential anticancer properties, more clinical trials are needed to establish its safety and efficacy in humans. Patients interested in alternative treatments should always consult with their healthcare provider before considering off-label uses.

For the full article, with transcript please visit https://themossreport.com

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If you are seeking a qualified professional for your care, including Ivermectin treatments, please consider the good folks at Progressive Medical Center in Dunwoody, GA. They have a wonderful facility, and Dr. Gez Agolli, who is the clinic director is someone we have every confidence in. Visit https://www.progressivemedicalcenter.com/ to learn more.

Ivermectin for Cancer in Dogs: Doses and Regimens Side Effects 0 Views • 24 days ago

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In this enlightening video, Dr. Andrew Jones thoroughly explores the innovative use of Ivermectin in the treatment of cancer in dogs. Discover the potential of this widely used antiparasitic medication as a cancer therapy, including the optimal dosages and treatment regimens. Dr. Jones discusses the latest research findings, demonstrating how Ivermectin can be effectively repurposed for cancer management in canines. He provides essential insights into the benefits and possible side effects, ensuring pet owners are well-informed about safe administration practices. Tune in to learn everything you need to know to provide the best care for your dog with the help of Dr. Jones' expert advice.

📖 Study References:
Ivermectin, a potential anticancer drug derived from an antiparasitic drug: https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC75051
Ivermectin inhibits canine mammary tumor growth: https://pubmed.ncbi.nlm.nih.gov/31375107/
Clinical Trials Using Ivermectin: https://www.cancer.gov/about-c....ancer/treatment/clin

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What Are the Long-Term Effects of Using Fenbendazole and Ivermectin for Cancer? Side Effects 0 Views • 24 days ago

What Are the Long-Term Effects of Using Fenbendazole and Ivermectin for Cancer? In this informative video, we discuss the use of fenbendazole and ivermectin as potential treatments for cancer. We'll cover the origins of these drugs, which are primarily known for their antiparasitic properties, and their recent interest in the oncology field. Our discussion will highlight the findings from laboratory and animal studies that suggest these drugs may have anticancer effects. However, we will also address the limitations of current research, particularly regarding their use in humans.

It's essential to understand the potential risks associated with using these drugs without proper medical guidance. We will explore the concerns surrounding side effects and the possible interactions with other medications that could arise from their use. Additionally, we will emphasize the importance of not delaying conventional cancer treatments in favor of unproven alternatives, as this could significantly impact health outcomes.

Join us for this essential conversation about the realities of using fenbendazole and ivermectin for cancer treatment. Remember to consult with healthcare professionals before making any decisions regarding your treatment options. Subscribe to our channel for more educational content on cancer care and treatment options.

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About Us: Welcome to the Oncology Support Network, your trusted source for comprehensive information and support in the field of oncology. Our channel is dedicated to empowering patients, caregivers, and healthcare professionals with the latest insights on cancer treatment, research breakthroughs, and wellness strategies. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Debunking the BBC debunk of ivermectin Side Effects 0 Views • 24 days ago

Ivermectin: How false science created a Covid 'miracle' drug

https://www.bbc.co.uk/news/health-58170809

BBC Reality Check

But the BBC can reveal there are serious errors in a number of key studies that the drug's promoters rely on.

but thousands of supporters, many of them anti-vaccine activists, have continued to vigorously campaign for its use.

Members of social media groups swap tips on getting hold of the drug, even advocating the versions used for animals

https://www.nature.com/articles/s41591-021-01535-y

Large pro-ivermectin Facebook groups have turned into forums for people to find advice on where to buy it, including preparations meant for animals.

The BBC can reveal that more than a third of 26 major trials of the drug for use on Covid have serious errors or signs of potential fraud.

The group of independent scientists examined virtually every randomised controlled trial (RCT) on ivermectin and Covid

Social media group

https://mobile.twitter.com/K_S....heldrick/status/1408

https://cosmosmagazine.com/hea....lth/covid/data-detec

That’s how they all met on Twitter

They've been working together remotely on an informal and voluntary basis during the pandemic.

Reference please

The BBC can reveal that more than a third of 26 major trials of the drug for use on Covid have serious errors or signs of potential fraud.

None of the rest show convincing evidence of ivermectin's effectiveness.

Dr Kyle Sheldrick, one of the group investigating the studies, said they had not found "a single clinical trial" claiming to show that ivermectin prevented Covid deaths that did not contain "either obvious signs of fabrication or errors so critical they invalidate the study".

Out of a total of 26 studies examined, there was evidence in five that the data may have been faked

On top of these flawed trials, there were 14 authors of studies who failed to send data back.

The independent scientists have flagged this as a possible indicator of fraud.

The sample of research papers examined by the independent group also contains some high-quality studies from around the world.

A recent study in Lebanon was found to have blocks of details of 11 patients that had been copied and pasted repeatedly

they have submitted a retraction to the scientific journal which published it

https://pubmed.ncbi.nlm.nih.gov/34073401/

Study from Iran

Another study from Iran seemed to show that ivermectin prevented people dying from Covid.

https://www.researchsquare.com..../article/rs-109670/v

The records of how much iron was in patients' blood contained numbers in a sequence that was unlikely to come up naturally.

Dr Morteza Niaee, who led the Iran study, defended the results and the methodology and disagreed with problems pointed out to him,

adding that it was "very normal to see such randomisation" when lots of different factors were considered

Ivermectin is generally considered a safe drug, though there have been some reports of side effects.

But indirect harm can come from giving people a false sense of security, especially if they choose ivermectin instead of seeking hospital treatment for Covid, or getting vaccinated in the first place.

Some groups regularly contain posts about conspiracy theories of ivermectin cover-ups, as well as pushing anti-vaccine sentiment or encouraging patients to leave hospital if they aren't getting the drug.

South African nurse dies

Instead of consulting a doctor, she continued with the ivermectin and got home oxygen.

What study are the BBC talking about?

https://pubmed.ncbi.nlm.nih.gov/34552263/

https://www.nature.com/articles/s41591-021-01535-y

https://www.medicalbrief.co.za..../ivermectin-papers-s

We recommend that meta-analysts who study interventions for COVID-19 should request and personally review IPD (independent patient data) in all cases,

In a similar vein, all clinical trials published on COVID-19 should immediately follow best-practice guidelines and upload anonymised IPD so that this type of analysis can occur.

https://ivmmeta.com

http://jja-contents.wdc-jp.com..../pdf/JJA74/74-1-open

Kitasato University, based on the judgment that it is necessary to examine the clinical effect of ivermectin to prevent the spread of uncertain COVID-19,

asked Merck & Co., Inc. to conduct clinical trials of ivermectin for COVID-19 in Japan.

This company has priority to submit an application for an expansion of ivermectin’s indications, since the original approval for the manufacture and sale of ivermectin was conferred to it.

However, the company said that it had no intention of conducting clinical trials.

Ivermectin clarification Side Effects 0 Views • 24 days ago

Ivermectin, is a Food and Drug Administration (FDA)-approved antiparasitic drug,

https://www.covid19treatmentgu....idelines.nih.gov/the

https://www.covid19treatmentgu....idelines.nih.gov/theivermectin/

Direct from official FDA site

used to treat several neglected tropical diseases,

including onchocerciasis, helminthiases, and scabies.

For these indications, ivermectin has been widely used and is generally well-tolerated

Ivermectin is not approved by the FDA for the treatment of any viral infection.

Proposed Mechanism of Action and Rationale for Use in Patients With COVID-19

(in vitro studies)

suggest that ivermectin acts by,

Inhibiting host importin nuclear transport proteins

Interfere with SARS-CoV-2 spike protein attachment to the human cell membrane

Some studies of ivermectin have also reported potential anti-inflammatory properties

Shown to inhibit replication of SARS-CoV-2 in cell cultures

COVID-19 medical misinformation policy

https://support.google.com/youtube/answer/9891785
https://support.google.com/youtube/answer/11161123

If you're posting content

Don't post content on YouTube if it includes any of the following:

Treatment misinformation:

Content that claims that there's a guaranteed cure for COVID-19
Content that recommends use of Ivermectin or Hydroxychloroquine for the treatment of COVID-19

Categorical claims that Ivermectin is an effective treatment for COVID-19

Claims that Ivermectin and Hydroxychloroquine are safe to use in the prevention of COVID-19

Other content that discourages people from consulting a medical professional or seeking medical advice

Prevention misinformation: Content that promotes prevention methods that contradict local health authorities or the WHO.

Claims that there is a guaranteed prevention method for COVID-19

Claims that any medication or vaccination is a guaranteed prevention method for COVID-19

Content that recommends use of Ivermectin or Hydroxychloroquine for the prevention of COVID-19
Claims that Ivermectin and Hydroxychloroquine are safe to use in the prevention of COVID-19

Monitoring, Adverse Effects, and Drug-Drug Interactions

The FDA first issued a warning in April 2020 that ivermectin intended for use in animals should not be used to treat COVID-19 in humans. This warning was updated and reiterated in 2021.

https://www.fda.gov/consumers/....consumer-updates/why

FDA, Recommendation

The Panel recommends against the use of ivermectin for the treatment of COVID-19, except in clinical trials

The Panel will continue to review emerging data on ivermectin use, including the results from 2 large, ongoing randomized controlled trials.

Clinical Trials

Several clinical trials evaluating the use of ivermectin for the treatment of COVID-19 are currently underway or in development.

Please see ClinicalTrials.gov for the latest information.

Bangkok

Egypt

Malaysia

Is this one of the two?

https://www.principletrial.org..../news/ivermectin-to-

Ivermectin to be investigated in adults aged 18+ as a possible treatment for COVID-19 in the PRINCIPLE trial
23 June 2021

Time line

https://www.principletrial.org..../news/the-principle-

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Ivermectin Side Effects

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