Rituximab Side Effects
Patient and physician considerations for switching between Rituxan IV and Rituxan Hycela, the subcutaneous formulation, during non-Hodgkin lymphoma treatment.
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In this week's Lupus Q&A session, Dr. Connie answers questions regarding the side effects of steroids and how to deal with them, rituxan infusions, and various side effects of Lupus general.
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Welcome to "Ocrevus, Kesimpta and Rituxan: How They Work and When to Use Them"! In this video, we will be exploring the mechanisms of action of three commonly used anti-CD20 B cell depleting medications: Ocrevus, Kisempta, and Rituxan.
Anti-CD20 B cell depleting medications are a type of immunotherapy that work by targeting and depleting specific types of immune cells called B cells. These medications are used to treat a variety of autoimmune and immune-mediated conditions, including multiple sclerosis (MS).
In this video, we will discuss how Ocrevus, Kesimpta, and Rituxan work in treating Multiple Sclerosis. Whether you are a person with MS, a care partner or a healthcare professional or a patient seeking information on anti-CD20 B cell depleting medications, this video is for you. Thanks for watching!
The Boster Center for Multiple Sclerosis accepts all major insurance carriers and accepts consults from around the globe, both in office and via telemedicine. www.BosterMS.com or call 614-304-3444 to schedule!
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COMMENT with your thoughts and questions below! Ocrevus, Rituxan and Kesimpta OH MY! I look forward to reading and responding!
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NOTE: Make sure to talk to your provider before ANY treatment decision. We hope to educate, empower and energize those impacted by Multiple Sclerosis. This channel consists of a collection of formal lectures and informal video clips about MS to help educate others. These videos do not provide medical advice and are for informational/educational purposes only. This video for example is about Ocrevus, Rituxan & Kesimpta and How they work in Multiple Sclerosis. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any of our videos. They are just to help educate you about the condition guys!
Nathan H. Fowler, MD, discusses how comorbidities factor into treatment planning and the impact of the use of rituximab-based regimens and maintenance in patients with follicular lymphoma.
For more resources and information regarding anticancer targeted therapies: http://targetedonc.com/
Peter Martin, MD, evaluates the decision to treat a patient with bendamustine/rituximab in the context of high-risk follicular lymphoma that has progressed following frontline R-CHOP therapy and rituximab maintenance.
For more resources and information regarding anticancer targeted therapies: http://targetedonc.com/
Kim was blindsided by her stage 4 follicular lymphoma diagnosis. Now in remission, she shares her entire treatment experience in-depth with thepatientstory.com. FULL TRANSCRIPT & STORY → https://www.thepatientstory.co....m/cancers/non-hodgki
There are three videos to check out. (TIME CODES BELOW!)
Video 1: How I Got Diagnosed | First Symptoms, Treatment Decisions (https://youtu.be/pO18FNVChsk)
Video 2: Going Through Treatment & Side Effects | Chemotherapy (https://youtu.be/2AwcvRDcYsc)
Video 3: Navigating Life After A Cancer Diagnosis | Survivorship, Impact of Cancer on Marriage, and more (https://youtu.be/US1q5reK8Xc)
VIDEO 2 TIME CODES:
(00:43) Chemo infusion schedule, getting blood drawn before
(3:32) Chemo side effects
(4:56) What helped prevent/lessen side effects
(8:21) Neulasta shot
(9:35) Constipation and what helped
(11:59) Port placement and experience
(13:54) PET/CT scan
(17:04) More details about rituximab (Rituxan) experience
(18:14) Learning of no evidence of disease (NED)
- - -
Join our patient and caregiver community!
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Diego Villa, MD, MPH, clinical associate professor, Division of Medical Oncology, The University of British Columbia, discusses a retrospective analysis evaluating bendamustine and rituximab as induction therapy in both transplant eligible and ineligible patients with mantle cell lymphoma.
For more resources and information regarding anticancer targeted therapies: http://targetedonc.com/
0:00
5:03 What does Rituximab do?
8:27 How long does it take for Rituximab to begin working?
10:58 What types of vasculitis does Rituximab treat?
11:34 2021 ACR/VF Guidelines Review
13:02 Adverse effects
17:23 Who can take this drug?
18:21 What have we learned about Rituximab since 2013?
20:07 The RAVE Trial
23:54 ADVOCATE Trial
26:14 Q: I am 65 years old. Can I take Rituximab for the rest of my life?
28:20 Q: I had a severe allergic reaction to Rituximab on the fourth administration of the drug. Is this common so late?
29:53 Q: Since a typical Rituximab infusion is every six months, is this to have an overlap of effectiveness
31:53 Q: Is Rituximab a first-line treatment for EGPA?
33:15 Q: Is it inevitable to fall out of remission while on Rituximab for long periods?
34:30 Q: What is the average time for B-cell regeneration after the last infusion?
35:31 Q: How long do you need to be off of Rituximab after pregnancy/
37:28 Q What is the ideal time for vaccinations before your next infusion?
39:10 Q: Have you come across anyone who has taken Rituximab and developed the illness connected to the JC virus?
40:48 Q: My B Cells are depleted. Does it make me more vulnerable to developing cancer?
42:31 Q: Is there any concern that going through Rituximab treatment can make us vulnerable to measles?
43:27 Q: If I had my Rituximab infusion yesterday, can I exercise today?
43:58 Q: Can I take vitamins and supplements when getting Rituximab?
45:35 Q: Has Rituximab use been associated with Microcytic anemia
46:02 Q: What are your thoughts about someone working from home as opposed to going to the office while taking Rituximab?
47:21 Q: For someone with kidney damage, will Rituximab make it worse?
What You Need to Know About Rituximab (Rituxan®)
July 2025
Visit the Vasculitis Foundation (www.vasculitisfoundation.org).
Hosted by Donna Gairns, National Nurse Manager Lymphoma Australia - Rebecca Beck, Lymphoma Care Nurse for NSW discusses what are monoclonal antibodies, how do they work and the common side effects experienced by patients.
Our immune system has antibodies that detect and destroy viruses or bacteria, including abnormal cancer cells. An antibody attaches to a specific molecule (antigen) on the surface of the cell. Once it binds to the antigen, it serves as a flag to attract other immune cells to attack and kill the cell.
Monoclonal antibodies are cancer treatments that are used in the management of many types of B-cell lymphomas. They are made in the laboratory and specially engineered to bind to the CD20 antigens that are on the surface of the malignant and healthy B-cells.
These drugs use the body’s immune system to then attack and fight the cancer cell.
For more information:
Lymphoma Australia fact sheets, including maintenance therapy
https://www.lymphoma.org.au/page/1218/fact-sheets
For more expert presentations, see Lymphoma Australia YouTube Channel
Does Rituximab Cause Hair Loss? In this informative video, we will discuss the relationship between Rituximab and hair loss. Rituximab, a medication commonly used for treating certain cancers and autoimmune diseases, is often associated with various side effects. One concern for many patients is whether this medication can lead to changes in hair growth. We will explore the potential for hair loss as a side effect, particularly in patients undergoing treatment for specific conditions.
We will also cover how hair loss can manifest in different ways and what patients might expect during and after their treatment. Understanding the nature of this side effect can help individuals make informed decisions about their treatment options and manage any concerns they may have. Additionally, we’ll emphasize the importance of communicating with healthcare providers regarding any side effects experienced during treatment.
Stay tuned for practical tips on how to address hair loss concerns and ensure you receive the support you need from your healthcare team. Don't forget to subscribe to our channel for more helpful discussions on oncology and related topics.
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About Us: Welcome to the Oncology Support Network, your trusted source for comprehensive information and support in the field of oncology. Our channel is dedicated to empowering patients, caregivers, and healthcare professionals with the latest insights on cancer treatment, research breakthroughs, and wellness strategies. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.
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Come along to my Rituximab infusion. I recently have switched to a Rituxan biosimilar called Truxima. I’ll share my patient experience, side effects, the infusion process and give you a tour of my infusion room.
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Andrew D. Zelenetz, MD, PhD, Vice Chair, Medical Informatics, Department of Medicine; Chief, Lymphoma Service, Memorial Sloan-Kettering Cancer Center, explains the impact that rituximab (Rituxan) has made in the treatment of patients with non-Hodgkin and B-cell lymphomas.
For more on lymphoma and other hematologic malignancies, visit http://www.onclive.com/special....ty/hematologic-cance
Is it safe to take B-cell depleting medications for multiple sclerosis such as Ocrevus, Rituximab, Kesimpta, and Briumvi continuously for many years? In this video, I explain the immune system can become weaker over time with continuous use, and low immunoglobin (antibody) levels can result in serious infections.
Notes:
Is rituximab 500mg just as good as rituximab 1000mg for MS? This deescalation study suggests that decreasing the dose to 500mg does not affect clinical, MRI, or serum NfL results over a 12 month period and may be safer. https://pubmed.ncbi.nlm.nih.gov/32840408/
Do you really need Ocrevus every 6 months? This study in Italy during the pandemic found that "extended interval dosing" was linked to more MRI activity but not disability progression or NEDA-3. https://pubmed.ncbi.nlm.nih.gov/36036858/
What happens if you delay Ocrevus due to fear of covid? Nothing! This retrospective study suggests that extended interval dosing compared to standard dosing did not significantly change relapses, disability progression, MRI activity. https://pubmed.ncbi.nlm.nih.gov/34261812/
An extended dosing interval for rituximab for patients with stable MS during the COVID-19 pandemic may be associated with a low risk of disease activity. https://nn.neurology.org/content/7/5/e825?utm_source=Twitter&utm_medium=organic
Living life without B cells: is repeated B-cell depletion a safe and effective long-term treatment plan for rheumatoid arthritis? https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC33921
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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.
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he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.
Rituximab is a monoclonal anti-CD20 antibody used to treat non-Hodgkin's lymphoma, chronic lymphocytic leukemia, Wegener's granulomatosis, pemphigus vulgaris, and rheumatoid arthritis.
In this video, let’s find found:
What is Rituximab? What class of drug is Rituximab?
What is Rituximab used to treat?
Who cannot use Rituximab?
What are the side effects of taking Rituximab?
How does Rituximab make you feel?
How to use Rituximab?
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Tags: Rituximab, Rituximab uses, Rituximab dosage, Rituximab mechanism of action, Rituximab indications, Rituximab contraindications, Rituximab side effect, Blitzima, Riabni, Ritemvia, Rituenza, Rituxan, antibody, Monoclonal antibody, non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura, pemphigus vulgaris, myasthenia gravis, Antineoplastics, Rituximab 10, DMARDs, Other; Antineoplastics, Anti-CD20 Monoclonal Antibodies