In this episode, I discuss a medication known as Benadryl (diphenhydramine).

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Diphenhydramine is a H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.

In this video, let’s find found:
What is diphenhydramine?
What is diphenhydramine used for?
Contraindication
What are the side effects of taking diphenhydramine?
How does diphenhydramine work?
How to use diphenhydramine?

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Tags: he-info, diphenhydramine, Benadryl, diphenhydramine uses, diphenhydramine dosage, diphenhydramine side effects, diphenhydramine mechanism, diphenhydramine indication, diphenhydramine contraindications, diphenhydramine mechanism of action, antihistamine, diphenhydramine hcl, diphenhydramine sleep aid, diphenhydramine pharmacology, diphenhydramine hydrochloride, antihistamine allergy, diphenhydramine capsules, diphenhydramine cream, diphenhydramine citrate, diphenhydramine cough syrup

Diphenhydramine is a antihistamine allergy drug that, when used in large amounts, provides sedative and deliriant effects. The experiences it provides are normally uncomfortable.

Diphenhydramine = DPH; Nytol; Sominex; Benadryl

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In this video, we dive into Benadryl and discuss how it works in the body and when you might use it. This medication (Benadryl), also known as diphenhydramine, is commonly used to treat allergies and allergic reactions. But Benadryl has some side effects you may not want. We will discuss that and more in our overview on Benadryl.

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Allergists are saying that Benadryl, a first-generation antihistamine, isn’t always the safest or most effective treatment for allergies. Our Second Look panel discusses why that’s the case and what the alternatives are.

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Using diphenhydramine as a sleep aid, Discuss this popular over-the-counter medication for sleep.
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This video is for informational purposes only. It not intended to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have seen in a video.

Antihistamine drugs are everywhere! While you’re used to the anti-allergy effects of commercially successful drugs like Benadryl and Claritin, popular drugs for motion sickness, peptic ulcers, and even antipsychotics started their lives as antihistamines. It also turns out that important concepts in pharmacology, like the receptor theory, and agonist and antagonist pharmacology, owe their development in part to the story of antihistamines.

☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️

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Full annotated script available for free on Patreon: https://www.patreon.com/posts/....antihistamines-10220
Blockbuster Drugs: the Rise and Decline of the Pharmaceutical Industry by Jie Jack Li https://amzn.to/3U4WnuM (affiliate link)
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Histamine pharmacology: from Sir Henry Dale to the 21st century (2020) https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC70129
Histamine receptors and antihistamines: from discovery to clinical applications (2014) https://pubmed.ncbi.nlm.nih.gov/24925401/
Histamine and itch (2014) https://www.ncbi.nlm.nih.gov/books/NBK200934/
Frontiers in Clinical Drug Research - Anti-Allergy Agents (2018) https://www.google.com/books/edition/Frontiers_in_Clinical_Drug_Research_Anti/EIJoDwAAQBAJ?hl=en&gbpv=0
Allergy https://www.ncbi.nlm.nih.gov/books/NBK545237/
Allergic rhinitis https://www.nature.com/articles/s41572-020-00227-0
Inverse Agonism and Functional Selectivity (2018) https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC61659
Histamine H1 Receptor https://www.sciencedirect.com/....topics/neuroscience/
Histamine and the antiallergic antihistamines: a history of their discoveries (1999) https://pubmed.ncbi.nlm.nih.gov/10444205/
Dale and Laidlaw isolate histamine (1910) https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC15129
Dale and Richards experiment with histamine (1911) https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC14026
Halpern discovers Phenergan https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC15911
The Claritin Effect; Prescription for Profit (2001) https://www.nytimes.com/2001/0....3/11/magazine/the-cl
As Blockbuster Claritin Goes Generic, Schering-Plough Pushes a Close Sibling (2002) https://www.wsj.com/articles/SB1016748743581330920

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⌛T I M E S T A M P S ⌛
0:00 intro
0:34 The Discovery of Histamine
5:46 The First Antihistamines
12:33 The Rise of Non-Drowsy (Second Generation) H1 Antihistamines
19:34 Tagamet: the first blockbuster

#historyofmedicine #medicalhistory

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0:16 Brand Vs Generic
0:29 Fact #1 What Hydroxyzine Treats
0:45 Fact #2 How Hydroxyzine Works
1:03 Fact #3 How Hydroxyzine Is Prescribed
2:07 Fact #4 Side Effects Of Hydroxyzine
3:07 Fact #5 How To Discontinue Hydroxyzine

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Over 6 million adults in America take a prescription sleep aid and another unknown but potentially double or triple that number take an over the counter sleep aid.

One of the most common is diphenhydramine (also known as Benadryl or Unisom brand names). Diphenhydramine works by blocking histamine activity as well as acetylcholine activity which provokes a drowsy state.

Acetylcholine is like a nerve cell manager and when its activity is shut off the coordination between neurons and the ability to file memory’s and information in an orderly fashion to be retrieved easily at a moments notice is broken.

Now consuming a diphenhydramine-based drug occasionally every 3-6 months isn’t likely to have any negative long term implications.

However, taken regularly like the majority of the patients I see coming in using them, can spell disaster for your cognition and memory long term.

In today's video, I will share some natural approaches to getting better sleep without compromising your health.

#DrWholeness #AccumulateHealth #BenadrylLongTermSideEffects

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Diphenhydramine is an antihistamine indicated for treating allergic conditions.

It can cause sedation and drowsiness. That's why it can also be used for treating insomnia. It can produce few anticholinergic side effects like dry mouth, blurred vision, constipation and urinary retention.

#diphenhydramine
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- This is lesson n# 86 in "A DRUG IN BRIEF" Series. In this video I'm gonna discuss almost all you need to know about Diphenhydramine Hydrochloride ( Benadryl ): What is Diphenhydramine? Uses, Dosage, Side Effects Precautions and mechanism of action

- In 3 minutes you'll learn:

- What is Diphenhydramine Hydrochloride ( Benadryl )?

- Diphenhydramine is a first-generation antihistamine. It competitively antagonizes histamine at the H1 receptor site. It also has strong sedating and anticholinergic properties.

- It is available as 25 mg tablets, syrup, cream and injection. It is also available in combination with a nasal decongestant and an analgesic to relief nasal and sinus congestion due to common cold or allergies. And you may also find it as softgels to be used as sleep-aid.

- Diphenhydramine is used in the treatment of seasonal and perennial allergic rhinitis; treatment of urticaria and angioedema; Parkinson’s disease and drug-induced, extrapyramidal symptoms, Insomnia; Motion sickness; Antitussive.

- Learn more about Diphenhydramine Hydrochloride ( Benadryl ) mechanism of action, uses, dosage, side effects, and precautions in this video...

- MORE "DRUG IN BRIEF" VIDEOS HERE:
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Benadryl (​​diphenhydramine) is an antihistamine. It’s commonly used to treat allergies, symptoms of the common cold, and itchiness. Benadryl may cause side effects for some, and knowing how to deal with side effects may improve your treatment experience. This video offers 3 different ways to cope with the most common Benadryl side effects: drowsiness, constipation, and dry mouth.

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#antihistamines #allergytreatment #allergyseason

In this video Doctor O'Donovan explains key things you need to know about cetirizine (brand names: Allacan, Benadryl Allergy, Piriteze Allergy, Zyrtek Allergy).

Cetirizine is an antihistamine medicine that helps the symptoms of allergies.

It's used to treat:

- hay fever
- conjunctivitis (red, itchy eye)
- eczema
- hives (urticaria) – an itchy, raised rash that’s usually caused by an allergic reaction
- reactions to insect bites and stings
- some food allergies

Cetirizine is known as a non-drowsy antihistamine. It's much less likely to make you feel sleepy than some other antihistamines.

Cetirizine is available on prescription, and to buy from pharmacies and shops.

It comes as tablets, capsules and as a liquid that you swallow.

Key facts

1. You'll usually take cetirizine once a day. Children aged under 12 years old take a lower dose twice a day.
2. Cetirizine is classed as a non-drowsy antihistamine, but some people still find it makes them feel quite sleepy. Do not drive or ride a bike if it makes you sleepy.
3. Common side effects include headaches, dry mouth, feeling sick, feeling dizzy and diarrhoea.
4. Some brands of cetirizine come as capsules. These may contain soya oil. Do not take cetirizine capsules if you’re allergic to peanuts or soya.

Some Benadryl products do not contain cetirizine, but a different antihistamine such as acrivastine.

**‘Reporting of side effects**

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at [a website address which links directly to the MHRA Yellow Card site].

By reporting side effects, you can help provide more information on the safety of this medicine.’

**********************************************************************

Content and TIMESTAMPS:

00:00 - Introduction
01:08 - What is Cetirizine and how does it work?
02:02 - Who can and can't take it?
03:22 - How and when to take it?
05:29 - Side effects
06:47 - Pregnancy and breast feeding information
07:30 - Interactions with other medications
08:00 Common questions
****************************************************************************
Further information from trusted sources:

Information from NHS: https://www.nhs.uk/medicines/c....etirizine/about-ceti

Cleveland Clinic (USA): https://my.clevelandclinic.org..../health/drugs/19298-

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The information within this video or on this channel is NOT designed to replace professional input, so if you have any medical issues please consult a medical provider. No professional relationship is being created by watching this video. Dr. O’Donovan cannot give any individual medical advice. All information should be verified for accuracy by the individual user. Dr O’Donovan accepts no responsibility for individual interpretation of data, although it is always accurate to the best of his knowledge at the time of the video being published. This is an EDUCATIONAL video. Images are used in accordance with fair use guidelines.

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Content provided via YouTube is for general information purposes ONLY. Information videos are not produced to provide individualised medical advice. Medical education videos on Doctor O'Donovan Medical Education Limited are not a substitute for professional professional medical advice, diagnosis or treatment. NEVER ignore professional medical advice because of something you have heard here. ALWAYS consult your doctor regarding any concerns about your condition or treatment. Information is accurate to the best of Doctor O'Donovan Medical Education Limited knowledge but may have errors or omissions - these are unintended and if raised the video will be reviewed in full.

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Date published: 28/01/2024. Next review date: 22/01/2027

This video examines the question and remark: Benadryl long term side effects! I WISH I had KNOWN! Benadryl is a common OTC medication and is also known as Diphenhydramine. The side effects of Benadryl( Diphenhydramine)are especially worrisome in the elderly.The long term side effects of Benadryl are examined in this video through a series of questions:

Read the entire article/transcript here: https://drthinkyourhealth.com/....benadry-l-long-term-

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⏰TIMESTAMPS:

00:00 Intro
00:37 What is Benadryl?
00:57 What is Benadryl used for?
02:43 Is it OK to take Benadryl as a sleep aid?
03:14 How quickly does Benadryl work?
03:29 Is Benadryl safe in older adults?
03:57 Can Benadryl cause Dementia?
04:28 How should I take Benadryl?(Diphenhydramine)
05:28 What are common side effects for Benadryl?
05:47 What are serious side effects?

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Sources:

1)Uptodate.com/Benadryl
2)https://jamanetwork.com/journa....ls/jamainternalmedic
3)Harvard/edu
4) https://www.rxlist.com/benadryl-drug.htm

Think Your Health provides general educational information on various topics on this YouTube video and channel as a public service, which should not be construed as medical, psychological or health advice. These are my personal opinions only.

#Benadryl #diphenhydramine



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#Benadryl #Diphenhydramine

The popular antihistamine Benadryl is not as safe as people think and the Canadian Society of Allergy and Clinical Immunology says the drug should be put behind the counter at pharmacies because of its side-effects.

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In this episode, I discuss a medication known as Benadryl (diphenhydramine).

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The Fifth Episode - Inside The Manic Mind.
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