Keytruda Side Effects


Medical oncologist, Mark Scholz, MD, answers questions all about immune therapies for prostate cancer. Topics include Provenge (Sipuleucel-T), Keytruda (Pembrolizumab), CAR T-cell therapy, and Leukine (Sargramostim).
0:08 What is immunotherapy in prostate cancer and how does it work?
1:23 Does Provenge have any side effects?
1:44 You've had ten years of experience treating patients with Provenge; how effective has it been in your patients?
3:02 Do you believe in giving Provenge to active surveillance patients? Is it approved for that use?
3:58 Can you explain how Keytruda works in prostate cancer?
5:41 How many patients have you treated with Keytruda and what success have you had with it?
6:15 When do you think Keytruda will get approved for prostate cancer?
6:40 If someone is interested in Keytruda, can any oncologist get them the medication?
7:02 What is CAR T-cell therapy and how will it affect future treatment?
7:59 What is Leukine, how does it work, and what is the side effect profile?
Don’t know your stage? Take the quiz: Visit http://www.prostatecancerstaging.org
To learn more about prostate cancer visit http://www.pcri.org
To receive the latest updates on prostate cancer and the PCRI, sign up for our online newsletter here: https://pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better individualized care. Feel free to explore our website or call our free helpline at 1 (800) 641-7274 with any questions that you have. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
The information on the Prostate Cancer Research Institute's YouTube channel is provided with the understanding that the Institute is not engaged in rendering medical advice or recommendation. The information provided in these videos should not replace consultations with qualified health care professionals to meet your individual medical needs.
#ProstateCancer #Prostate #MarkScholzMD


Margaret Gatti-Mays, MD, MPH, a breast cancer oncologist at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James), explains the side effects that can occur from immunotherapy. Side effects can be similar to autoimmune disorders such as rheumatoid arthritis and lupus. As immunotherapy becomes the standard of treatment in cancer, the OSUCCC–James has a specialty clinic available to specifically address side effects from this treatment.
#cancerimmunotherapy #sideeffects
Learn more at https://go.osu.edu/CrgR


PCRI's Alex asks medical oncologist Mark Scholz, MD, about the immunotherapy Keytruda (Pembrolizumab) which oncologists have begun using on a compassionate-use basis for the treatment of advanced prostate cancer.
0:05 How does Keytruda work?
0:34 Does Keytruda have permanent side effects?
1:10 Can Keytruda's side effects be mitigated?
1:41 How does Keytruda compare to other immune therapies like Provenge or Olaparib?
2:26 Does Keytruda ever produce "miraculous" results?
3:01 How is Keytruda administered?
3:18 How can a patient get access to Keytruda?
3:40 Can any medical oncologist access Keytruda through Merck?
4:01 How expensive is it to access Keytruda?
Don’t know your stage? Take the quiz: Visit http://www.prostatecancerstaging.org
To learn more about prostate cancer visit http://www.pcri.org
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better individualized care. Feel free to explore our website or call our free helpline at 1 (800) 641-7274 with any questions that you have. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
The information on the Prostate Cancer Research Institute's YouTube channel is provided with the understanding that the Institute is not engaged in rendering medical advice or recommendation. The information provided in these videos should not replace consultations with qualified health care professionals to meet your individual medical needs.
#ProstateCancer #Prostate #MarkScholzMD


आज डा विनीत, दिल्ली के ऑन्कोलॉजिस्ट इम्युनोथेरेपी से जुड़े कैंसर उपचार के जोखिमों और साइड इफेक्ट्स पर महत्वपूर्ण जानकारी देंगे। खतरों और मृत्यु की संभावनाओं को उजागर करते हुए, यह चर्चा जीवन रक्षा दरों और इम्युनोथेरेपी अनुसंधान पर केंद्रित है। इम्यून रिलेटेड एडवर्स इवेंट्स (आई.आर.ए.ई) चरण 1 से स्टेज 4 तक के कैंसर के खिलाफ लड़ाई में किसी को भी हो सकते है। वीडियो में इन प्रभावों की घटना, जोखिम, रोकथाम और प्रबंधन की जानकारी दी गई है। इसमें निवोलुमैब (ओपडिटा), पेम्ब्रोलिज़ुमैब (कीट्रुडा), आवेलूमब (बवेनसिओ), दुर्वालूमब (इम्फिंज़ी)और इपिलिमुमैब (येरवोय) जैसी प्रमुख इम्युनोथेरेपी दवाओं का जिक्र है, और निमोनिया, हेपेटाइटिस, किडनी और हार्ट फेल्योर जैसी जटिलताओं के साथ-साथ सफ़ेद दाग (विटिलिगो) और त्वचा पर धब्बो जैसी आम समस्याओं पर भी बात की गई है। यह सामग्री भारतीय रोगियों को इम्युनोथेरेपी के जोखिमों और रोकथाम के उपायों के बारे में महत्वपूर्ण जानकारी देकर सशक्त बनाती है। दिल्ली के मशहूर कैंसर स्पेशलिस्ट मेडिकल ऑन्कोलॉजिस्ट डा विनीत गोविंदा गुप्ता MBBS (AIIMS) , MD (AIIMS), DM (AIIMS), गोल्ड मेडलिस्ट से जानें।
यदि इस वीडियो के अलावा आपके कोई सवाल है तो हमें व्हाट्सप्प, या ईमेल से संपर्क करें। चैनल को सब्सक्राइब करें।
फ़ोन: +919013812875, +917290928042
वेबसाइट: http://drvineetgovinda.com
इ मेल: [email protected]
फेसबुक: @drvineetgovindagupta
ट्विटर: @drvineetgovinda
00:00 Introduction परिचय
02:13 What is cancer immunotherapy कैंसर इम्म्युंथेरपी क्या होती है
02:58 Prevention of immunotherapy side effects इम्मुनोथेरपी के साइड इफेक्ट्स कैसे रोकते है
05:21 Common side effects of immunotherapy इम्मुनोथेरपी के साधारण या आम साइड इफेक्ट्स
07:10 Dangerous side effects of immunotherapy इम्मुनोथेरपी के खतरनाक साइड इफेक्ट्स
09:35 Treatment of immune related adverse events इम्यून रिलेटेड एडवर्स इवेंट्स का इलाज
11:34 Immune related side effects and spread of cancer इम्यून साइड इफेक्ट्स और कैंसर का खतरा
13:05 Can immunotherapy cause death of cancer patient क्या इम्मुनोथेरपी से मरीज़ की मौत हो सकती है
14:08 Contact information संपर्क


The first webinar in our 2020 Lung Cancer Webinar series is: Immunotherapy treatment and side effects: Practical support through self-management.
Learn more about what immunotherapy is, why it is used in lung cancer treatment and hear about commonly reported side effects. Clinical Nurse Consultant Kelli Brittan, will discuss practical ways to self-manage side effects and Lung Foundation Australia’s Lung Cancer Support Nurse, Nicole, will share how she supports people living with lung cancer in her role.
To register for our Live Well, Breathe Better webinar series, visit: https://lungfoundation.com.au/....patient-education/?e


Are you interested in immunotherapy? Do you want to learn about side effects of immunotherapy and how it works? Watch the webinar, Managing Immunotherapy Side Effects, that took place July 21, 2016. The webinar features two experienced presenters, followed by a Q&A with participants.
Today’s presenters include:
• Kristen Linney, Registered Nurse, Duke University Hospital
• Ashley Haller, ANP-BC, Nurse Navigator, Duke University Hospital
Topics include:
• What to expect with immunotherapy
• Do side effects mean immunotherapy is working?
• Collaboration with your health care team
For more information about immunotherapy, please visit:
https://www.cancersupportcommu....nity.org/immunothera
The program was made possible with support from AstraZeneca and Merck.
0:00 Introduction and CSC Resources
4:15 Today’s Presenters
4:43 What is Immunotherapy?
7:27 Side Effects from Immunotherapy
9:05 Actions You Can Take
10:11 Audience Questions
58:40 Thank You


What is immunotherapy? What are the side effects? In this video, Dr. Jennifer Griggs explains everything you need to know about immunotherapy for breast cancer.
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Dr. Evan Yu of Seattle Cancer Care Alliance explains some of the potential side effects caused by immunotherapy, and how these side effects are generally much lower in toxicity than those caused by chemotherapy.
Learn more about immunotherapy: http://ow.ly/tW0d309pIxE
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Amanda is currently undergoing an immunotherapy called Keytruda. In this cancer vlog, she describes how her immunotherapy for cancer works, how long the treatment is, and the side effects.
After going through two rare cancers, Amanda was most recently diagnosed with extra ovarian primary peritoneal carcinoma. She started feeling fullness/pressure in her pelvis and scans eventually revealed a grapefruit-sized mass in her pelvis, with part of it being a solid tumor. After surgery to remove the mass, the pathology revealed her diagnosis as extra ovarian primary peritoneal carcinoma, which is a rare gynecologic cancer.
Amanda is in full remission, but she will continue on the immunotherapy for another year.
#cancerstories #cancerpatient #cancersurvivor #patientstories #thepatientstory #CUP #EOPPC #chemotherapy #rarecancer #lynchsyndrome #keytruda #immunotherapy #immunotherapysideeffects
The Patient Story:
The Patient Story is led by a dedicated team of medical, editorial, and video experts, committed to authentically portraying the cancer patient experience. Sharing your story holds transformative power, culturally and personally. We handle each narrative with utmost care, compassion, and scientific rigor.
Our editorial process adheres to the highest journalistic standards, ensuring medically researched, vetted, and fact-checked content. Backed by experienced medical professionals, we offer insights into the latest medical advancements.
Beyond patient narratives, we provide comprehensive coverage of cancer news and medical resources. From symptoms to clinical trials, insurance, finances, and support groups, we offer guidance in a humanized manner.
[Video Chapters]
00:00 Who I Am
00:28 The first symptoms of my rare cancer
02:00 They found a mass in my pelvis
03:15 My actual diagnosis
03:35 I didn't want to lose my hair
04:55 Deciding my treatment plan
05:20 It was a no brainer to do KEYTRUDA
05:55 I'm in remission, but I am continuing KEYTRUDA
06:22 How I'm tolerating the immunotherapy
07:21 How my immunotherapy works
08:15 My side effects
09:01 More on how it works when I go in for the immunotherapy
10:32 Look into the resources at the hospital
11:06 My biggest advice
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The interview has only been edited for clarity. The interview has only been edited for clarity.
How My IMMUNOTHERAPY Works! - Amanda | Keytruda | The Patient Story
https://youtu.be/TAg11rm4ZYc


Immunotherapy for cancer treatment can sometimes produce certain side effects. However, these side effects are very different to those of other cancer treatments, such as chemotherapy, and are generally more of an inflammatory nature, which could affect any part of the body. Dr Hendrik Tobias Arkenau, a leading medical oncologist at the Sarah Cannon Research Institute in London, explains in more detail the possible side effects of immunotherapy and what patients should do if they experience them.
Book a consultation with Dr Arkenau: https://www.topdoctors.co.uk/d....octor/hendrik-tobias


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Educated and empowered patients have better outcomes. We've partnered with hundreds of medical experts and doctors to help you learn more about your disease.


Immunotherapy is extending life for many patients with cancer, but the treatments often come with side effects that can negatively impact quality of life.
A new clinic at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) and Pelotonia Immuno-Oncology Institute aims to help manage the autoimmune side effects of immunotherapy-based cancer treatment and allow patients to live the fullest life possible both during cancer treatment and long-term as a survivor.
Learn more about cancer care and research at The Ohio State University:
Home: https://cancer.osu.edu
Blog: https://cancer.osu.edu/blog
News: https://cancer.osu.edu/news
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#immunotherapy #CancerImmunotherapy #cancer


Learn more about lung cancer at http://www.YouAndLungCancer.com
Lung cancer expert Dr. Joseph Leach of Allina Health Cancer Institute shares an overview of the side effects that may be associated with immunotherapy for lung cancer. He explains that some people experience very few side effects, while others have more serious complications and discusses some examples. It is important to let your doctor know right away about any side effects you experience. Your doctor can help you get them under control quickly.


Keytruda, the cancer drug used to treat the melanoma that had spread to former President Jimmy Carter’s brain, is already approved as a second-line cancer therapy, but a new study is showing it is effective as a first-line treatment. Dr. Natalie Azar tells TODAY that study participants on Keytruda were doing so well that doctors ended the trial early because it would be unethical not to give all the patients the drug.
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Keytruda, Immunotherapy Drug That Aided Jimmy Carter’s Cancer, ‘A Huge Deal’ | TODAY


Immunotherapy can cause certain side effects, however, these will depend on the type of immunotherapy treatment you are being given. Fortunately, many of the side effects of immunotherapy can be managed well. Dr Mark Tuthill, a leading medical oncologist, explains further.
Make an appointment online with Dr Tuthill: https://www.topdoctors.co.uk/doctor/mark-tuthill


Results from the phase 3 randomized, open-label KEYNOTE-204 trial suggests that Keytruda (pembrolizumab) is superior to Adcetris (brentuximab vedotin) in patients with relapsed or refractory classic Hodgkin lymphoma. Moreover, the results showed manageable side effects and toxicity, according to Dr. John Kuruvilla.
Kuruvilla, from the Princess Margaret Cancer Centre in Toronto, spoke with CURE®’s sister publication, CancerNetwork®, to discuss the noted side effects seen in the study and what clinicians and patients need to know about this treatment.
Transcription:
With the drugs, there is certainly lots of experience in routine clinical use, so we didn't see anything particularly new or surprising, but because the drugs work with different mechanisms we saw differential toxicity.
So, with brentuximab the common things that you see are things like peripheral neuropathy, largely improving or self-limited when the drug is held, or the dose reduced. With pembrolizumab we saw a lot of the immune-related adverse events that are fairly common for these types of drugs, they're fairly minor, things like hyper-thyroids and those sorts of things that are fairly common create grade 1 or 2 toxicities.
The one thing a lot of clinicians and patients need to know a little bit about is pneumonitis and so this was seen in about 10% of the patients who used Keytruda. IT was grade 3 or 4 in a little over 5% of patients who received the drug. Again, thankfully no patient-related deaths were seen in patients with these types of toxicities.
It could be successfully managed with steroids in the majority of patients, so it's important toxicity to highlight but certainly did not limit the effectiveness of the drug.
View more at http://curetoday.com/
CURE: Combining science and humanity to make cancer understandable.


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Comprehensive guide to treatment options for BPH, prostatitis, and prostate cancer. Covers lifestyle modifications, medications, minimally invasive therapies, surgery, radiation, hormone therapy, chemotherapy, immunotherapy, and supportive care.
#ProstateTreatment #BPHRelief #ProstateCancerCare #MensHealthSupport #MinimallyInvasive.
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If you or your loved one is interested in immunotherapy, it is important to know about the possible side effects of immunotherapy treatments. Immunotherapy side effects are generally different from the side effects of other cancer treatments, like chemotherapy or radiation therapy. Some immunotherapy side effects may occur right away. Others may not occur for days, weeks, or months after treatment. Every cancer patient receiving immunotherapy should talk to their doctor about possible side effects. Watch this 10 minute guide to learn more. This is the second guide in the Immunotherapy eLearning series.
Links:
Immunotherapy Side Effects: https://www.cancersupportcommu....nity.org/immunothera
Resource Guide: https://www.cancersupportcommu....nity.org/sites/defau
00:00 Introduction
00:23 What is Immunotherapy?
01:11 Treatment Side Effects
04:33 Serious Side Effects


Although side effects from immunotherapy cancer treatment are rare, new research underscores the importance of early recognition. Roswell Park's Dr. Igor Puzanov is a co-author of a case study in which two patients developed myocarditis after receiving immunotherapy for melanoma. Learn more: https://goo.gl/USvyK4


Keytruda is a prescription medication used to treat certain cancers, including lung cancer, breast cancer, Hodgkin lymphoma, and many more.
Learn more about Keytruda: https://www.drugs.com/keytruda.html
It is a type of immunotherapy that helps the immune system detect and fight cancer cells.
Depending on the stage and type of cancer, it can be used alone or with chemotherapy, radiotherapy, or surgery.
Keytruda works by blocking a protein called PD-1 on the surface of certain immune cells called T cells. Once PD-1 is blocked, the T cells are more able to find and kill cancer cells.
This medicine is given as a slow infusion into a vein over 30 minutes and is usually given every 3 to 6 weeks.
The most common side effects when used alone are tiredness, muscle and joint pain, rash, diarrhea, fever, cough, reduced appetite, itchy skin, difficulty breathing, constipation, pain, abdominal pain, nausea, and hypothyroidism.
These side effects can occur in 20% or more of patients.
This is not a complete list of side effects, and others may occur.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Always consult with your healthcare provider.


Jeffrey S. Weber, M.D., Ph.D., of NYU Langone Health discusses our current understanding of the side effects that may result from immunotherapy as well as current strategies that are being explored to minimize these potentially harmful side effects and improve the patient experience. #CRIwebinar https://www.cancerresearch.org/
Dr. Jeffrey S. Weber is the deputy director of NYU Langone Health’s Perlmutter Cancer Center, where he works with a multidisciplinary team of medical and surgical oncologists, dermatologists, and pathologists to treat patients with melanomas ranging from the most common to the most complex.
The "Cancer Immunotherapy and You" webinar series is produced by the Cancer Research Institute and is hosted by our science writer, Arthur Brodsky, Ph.D. The 2020 series is made possible with generous support from Bristol-Myers Squibb, ALkermes, and Foundation Medicine.
Browse our Cancer Immunotherapy and You Webinar Series playlist on YouTube or visit the Webinars page on our website to see other webinars in this series. https://www.cancerresearch.org/events/webinars
Established in 1953, the Cancer Research Institute (CRI) is a 501(c)(3) nonprofit organization dedicated to harnessing our immune system’s power to control and potentially cure all cancers. Our mission: Save more lives by fueling the discovery and development of powerful immunotherapies for all types of cancer. To accomplish this, we rely on donor support and collaborative partnerships to fund and carry out the most innovative clinical and laboratory research around the world, support the next generation of the field’s leaders, and serve as the trusted source of information on immunotherapy for cancer patients and their caregivers. https://www.cancerresearch.org
Cancer Research Institute is a registered 501(c)(3) nonprofit under EIN 13-1837442. Donations are tax-deductible to the fullest extent allowable under the law.


Thoracic oncologist Dr. Jyoti Patel gives patients an easy-to-follow overview on side effects they might experience during immunotherapy treatment for cancer, recognizing symptoms, and talking with the health care team.
More Information
ASCO Answers Fact Sheet: Understanding Immunotherapy (PDF): https://www.cancer.net/sites/c....ancer.net/files/asco
Side Effects of Immunotherapy: https://www.cancer.net/navigat....ing-cancer-care/how-
What You Need to Know About Immunotherapy Side Effects: https://www.cancer.net/blog/20....18-02/what-you-need-
What It’s Like Taking Immunotherapy to Treat Cancer: https://www.cancer.net/blog/20....17-08/what-its-takin
Understanding Immunotherapy: https://www.cancer.net/navigat....ing-cancer-care/how-
00:00 Introduction to immunotherapy
00:27 Introduction to immunotherapy side effects
01:25 Potential side effects of immunotherapy
02:17 What to know about severe side effects from immunotherapy
02:58 Why it's important to track side effects when taking immunotherapy
03:13 What to know when taking immunotherapy along with other types of treatments
04:18 Where to find credible information about immunotherapy and related side effects