Patients with high platelet reactivity on standard-dose clopidogrel in conjunction with a drug-eluting stent for stable coronary disease obtain markedly greater platelet inhibition by switching to prasugrel at 10 mg/day than by doubling the clopidogrel dose to 150 mg/day, according to the Italian RESET trial. See the related story at http://tinyurl.com/cjqlryw

#Ticagrelor Can Be Discontinued 2 3 Days Prior to #CABG without Increasing #Bleeding Risk
According to new randomized data, in patients with ACS, performing CABG within a couple of days after ticagrelor cessation is noninferior to waiting 5 or 6 days in terms of bleeding events. Moreover, patients with delayed CABG had more presurgical ischemic events and longer hospital stays.
To prevent bleeding, current US guidelines recommend waiting at least 5 days to perform nonurgent CABG on patients with ACS who had been taking ticagrelor, while European guidelines shorten that period to at least 3 days.

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BRILTICAR 90
Ticagrelor 90 mg Tablets

BRILTICAR (Ticagrelor) is in a class of medications called Antiplatelet medications.

INDICATION :
It is generally used for the Prevention of heart attack or stroke

MECHANISM OF ACTION :

BRILTICAR (Ticagrelor) is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.

DOSAGE :
General dose : 1 Tablet once a day or as directed by the Physician.



Reference : www.1mg.com


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Have you heard of nattokinase? Check out the potential effects it can have on your heart and brain. 

Find Out More at drberg.com:  http://bit.ly/2U4Yj88

DATA:
https://www.sciencedirect.com/....science/article/pii/
https://www.karger.com/Article/Abstract/205051
https://link.springer.com/arti....cle/10.1007/s00449-0
https://journals.sagepub.com/d....oi/full/10.1177/1177

Timestamps
0:07 What is nattokinase? 
0:12 Vitamin K2
0:34 Nattokinase benefits
0:46 A possible alternative to aspirin
0:56 More health benefits of nattokinase for the heart and brain

Today we're going to talk about nattokinase and clotting, as well as some other nattokinase benefits. 

Nattokinase is an enzyme that comes from nato. Nato is a fermented soybean. Nato is a really good source of vitamin K2. Vitamin K2 is great to help pull calcium build-up out of the arteries. Nattokinase may also be helpful for those with endometriosis, pulmonary embolism, or cirrhosis. 

Many people take nattokinase as an alternative to aspirin to help lower the chance of stroke. Nattokinase may help get rid of clots and act as a natural blood thinner.

More potential health benefits of nattokinase for the heart and brain:

• Antithrombotic 
• Antihypertensive
• Anticoagulation
• Anti-atherosclerosis
• Neuroprotective



Dr. Eric Berg DC Bio:
Dr. Berg, 56 years of age is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of The New Body Type Guide and other books published by KB Publishing. He has taught students nutrition as an adjunct professor at Howard University. He no longer practices, but focuses on health education through social media.

Follow us on FACEBOOK: fb.me/DrEricBerg



ABOUT DR. BERG: http://bit.ly/2S1jgxZ
Disclaimer:
Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients so he can focus on educating people as a full time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

Thanks for watching! I hope this video helps you better understand nattokinase.

Learn more about this medication: Ticagrelor

- Indication: 00:00
- Administration: 00:11
- Side effects: 00:15
- Interaction with food/drugs: 01:18

Learn about identifying drug allergies if you are taking this for the first time:
https://youtu.be/-fmDV-Vb7Rc

Read more about your medication here:
https://www.healthhub.sg/a-z/m....edications/ticagrelo

This video is jointly developed by NHG Health pharmacists and the Lee Kong Chian School of Medicine Digital Learning team.

The content of this video is contributed by the Pharmaceutical Society of Singapore.

Information presented may vary for individuals and does not substitute for professional medical advice.

Watch this video to learn about antiplatelet medications ASA and Ticagrelor.
To learn more, go to the Manitoba ACS Network website (https://www.mbacsnetwork.ca/medications)

Disclaimer: The educational materials provided herein are for general reference and should not replace the advice you receive from your care providers.

Over 40% of people who have a stroke have another one within 10 years. Dhineli Perera chats to clinical pharmacologist Chris Tremonti about the drugs used to lower the risk of a secondary ischaemic stroke or TIA. See also: https://www.nps.org.au/austral....ian-prescriber/podca

Hentet fra: https://accscientificsession.acc.org/
Følg ACC2020 Live: https://virtual.acc.org/
----------------------
https://www.healthtalk.no/

Ticagrelor is a non thienopyridine antiplatelet agent belonging to a class known as cyclopentyl triazolo-pyrimidines. This binds to a site different from ADP, but blocks all the actions of ADP, acting as a reversible allosteric antagonist. It is not a prodrug and does not require activation by the liver cytochrome P450 pathway. It is rapidly absorbed after oral intake with a bioavailability of about one third and a peak plasma concentration at one and a half hours. The main metabolite is also pharmacologically active. Excretion of the drug is mainly by the hepatic route and renal excretion is less than one percent, hence does not require dose adjustment in renal disease.

PLATO trial was double blind phase III trial comparing ticagrelor and clopidogrel, involving over eight hundred and sixty centers in more than forty countries. 18,624 patients with acute coronary syndrome were evaluated and there was no increased overall bleeding risk noted with ticagrelor. But there was an increase in the non coronary artery bypass related bleeding including fatal intracranial bleed. Vascular events were lesser with ticagrelor compared to clopidogrel. The offset of action is faster with ticagrelor as the action is reversible and does not need the generation of new platelets.
Web: https://johnsonfrancis.org/pro....fessional/ticagrelor

Ticagrelor is used for prevention of heart attack and stroke. It decreases the chances of having another heart attack or stroke.

How Ticagrelor works
Ticagrelor is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.

Common side effects of Ticagrelor
Nausea, Dizziness, Vertigo, Increased uric acid level in blood, Shortness of breath, Gout, Headache, Fainting, Hypotension (low blood pressure), ECG changes, Increased creatine phosphokinase (CPK) level in blood


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Dr. Hsin-Yi Huang, a Post-Doctoral Research Fellow in the School of Pharmacy at the National Taiwan University in Taipei, shares insights from her article appearing in the November 2023 issue of Mayo Clinic Proceedings, where she found that although ticagrelor and clopidogrel have comparable results, ticagrelor has a higher risk of intracranial hemorrhage, and thus clinicians should use caution when prescribing it to acute myocardial infarction patients with a prior history of ischemic stroke. Available at: https://mayocl.in/3EU1KVj

Watch the full video on Radcliffe Cardiology: https://www.radcliffecardiolog....y.com/video-index/tw

Dr George Dangas (Mount Sinai Hospital, New York, NY, US) discusses the results of the TWILIGHT-Stent trial, presented at ESC 2021. This study examined the incidence of ischemic and bleeding events in patients treated with contemporary drug-eluting stents over 3-15 months. This trial also examined ticagrelor monotherapy vs ticagrelor with aspirin.

Questions:
1. What were the main aims of TWILIGHT-Stent?
2. What are your key findings?
3. What are the next steps?

Filmed remotely from New York, NY, 2021.

Interviewer: Jordan Rance

Radcliffe Cardiology is a dynamic, digitally-focused producer & publisher of Cardiovascular, Renal and Metabolic (CVRM) content for physicians worldwide. We aim to assist in the continuous education of physicians within the cardiology fraternity, generating a range of clinical content through collaboration with leading cardiologists from around the globe.

Stefanie Schuepke presenter of the ISAR REACT 5 trial explains the background and findings of this major trial. ISAR REACT 5 is the first large-sized trial which compared prasugrel and ticagrelor in ACS. The previously presented PRAGUE 18 trial was smaller and ultimately inconclusive. Hence, for the first time, we have evidence comparing the two drugs in a large scale randomized setting.

View a written analysis of this trial here:
https://www.pcronline.com/News..../Whats-new-on-PCRonl
Participate in a cardio poll regarding the results of ISAR REACT-5 :
https://www.pcronline.com/News..../Cardio-Poll/ISAR-RE
#ESCCongress

What is #Axcer Tablet used for?
Is Axcer and #ticagrelor the same?
Is Axcer and #brilinta the same?
How long should you take ticagrelor?

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✅ Review about TICAGRELOR (BRILINTA): Side effects, uses, dosage (tablets 90 mg), warnings, precautions, mechanism of action (moa), commercial name (brilinta) and answers to questions like: what is ticagrelor?, how does ticagrelor (brilinta) work?, What is ticagrelor used for?, What is brilinta used for?❤️ Suscribe: https://www.youtube.com/c/Medi....cinesDiseases?sub_co

More information about active ingredients here: https://activeingredients.online

Importance of medication to reduced the ongoing effects of atherosclerosis in patients with proven heart disease - secondary prevention

------------------
Visit website: https://www.thekeyholeheartclinic.com

✅ Review about TICAGRELOR (BRILINTA): Side effects, uses, dosage (tablets 90 mg), warnings, precautions, mechanism of action (moa), commercial name (brilinta) and answers to questions like: what is ticagrelor?, how does ticagrelor (brilinta) work?, What is ticagrelor used for?, What is brilinta used for?❤️ Suscribe: https://www.youtube.com/c/Medi....cinesDiseases?sub_co

More information about active ingredients here: https://activeingredients.online

What Is Ticagrelor? In this informative video, we will discuss Ticagrelor, a medication that plays a significant role in preventing heart attacks and strokes. We'll explain what Ticagrelor is, how it works, and the specific class of medications it belongs to. Understanding the mechanism of action is important for grasping how Ticagrelor helps reduce the risk of blood clots in patients with acute coronary syndrome or a history of heart attacks.

We will also cover the typical dosage and administration of Ticagrelor, highlighting its rapid onset of action and how it differs from older antiplatelet medications. Additionally, we will touch on potential side effects associated with Ticagrelor, such as the increased risk of bleeding and other reactions that may occur. Monitoring is essential for patients on this medication, and we will emphasize the importance of discussing any concerns with healthcare providers.

Join us for this comprehensive discussion on Ticagrelor and its role in cardiovascular health. Don't forget to subscribe to our channel for more educational content on medications and health topics.

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#Ticagrelor #Antiplatelet #HeartHealth #Cardiovascular #Medication #BloodClots #Adenosine #HeartAttackPrevention #AcuteCoronarySyndrome #HealthEducation #Pharmacy #PatientCare #MedicationSafety #SideEffects #DosageGuidelines

About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Additional effective antiplatelet agents in your armamentarium for treating patients with STEMI are always welcome. Before the Prague 18 trial, two of these – prasugrel and ticagrelor – had each been compared separately to clopidogrel, but had never been compared directly to each other. Join Dejan Milasinovic (Serbia) as he reports from ESC Congress 2016 the details of this illuminating trial: What were the primary and secondary endpoints? How did each of these agents perform? What is the importance of the so-called “neutral” results? Learn why the results of Prague 18 offer additional choices for DAPT today…

For more on this subject, please visit https://www.pcronline.com/

In the April 22nd issue of JACC, Mahaffey and colleagues return to the PLATO trial to look at the treatment effect on subsequent MIs and event adjudication. This interview with Kenneth W. Mahaffey, MD Professor of Medicine, Stanford
University, was conducted at ACC.14 in Washington, DC.

Further reading:
Mahaffey KW, et al. J Am Coll Cardiol 2014;63:[online before print]
http://content.onlinejacc.org/....article.aspx?article

This video has subtitles.

MedTap is a medicines information app developed by NHS clinicians. MedTap offers short videos from NHS staff on your medicines, in clear language, that you can access whenever you need.

•       How and when to take your pills
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MedTap is available to download via the Apple App Store or Google play for android
 
For more information please visit: www.guysandstthomas.nhs.uk/MedTap

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Tomas Jernberg, MD, PhD, FESC, MPH & Associate Professor of Cardiology at Karolinska Institute and Uppsala Clinical Research discusses outcomes in patients treated with ticagrelor or clopidogrel after acute coronary syndrome: Experiences from SWEDEHEART Registry at the American College of Cardiology 65th Annual Scientific Session & Expo (ACC.16).

MDLinx Conference Coverage - American College of Cardiology 65th Annual Scientific Session & Expo (ACC.16): http://www.mdlinx.com/cardiolo....gy/conference-interv

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