Thiazides for Hypertension.

This video was made by Shivani Sharma, 2021 Pharmacist Candidate. He will review: Patient consultation points, indications, dosing and adjustments, mechanism of action, side effects, and monitoring parameters.

Atenetic (Atenolol/Chlorthalidone) tablets are used in the management of hypertension: This is a combination product (contains two drugs) which may be suitable for use when satisfactory control of blood pressure cannot be obtained with either drug is used alone.

Discover the uses and side effects of Chlorthalidone, a key medication for high blood pressure & fluid retention, on our channel. Learn about Chlorthalidone's impact on urine production, electrolyte imbalances, dehydration, and more. Understand the importance of blood tests & monitoring with Chlorthalidone treatment. Stay informed about Chlorthalidone's effects on potassium, sodium, & calcium levels, plus glucose & lipid metabolism. Note: Content is for informational purposes only, not medical advice. Always consult a healthcare provider.

Chlorthalidone for Hypertension

This video was made by Raymond Chau, 2021 Pharmacist Candidate. He will review: Patient consultation points, indications, dosing and adjustments, mechanism of action, side effects, and monitoring parameters.

You've heard of Lasix, but is it the right choice for managing high blood pressure? Dr. Subodh Chaturvedi reveals a crucial medical distinction! 💡
While Lasix (Furosemide) is a powerful diuretic, its effect is rapid and short-lived (like a 100m sprint 💨). This makes it great for acute situations but not for steady, 24/7 blood pressure control.
For chronic hypertension, doctors prefer long-acting diuretics like Chlorthalidone or HCTZ. They work gently over 40-50 hours, providing the stable, marathon-like control your body needs. 🏃‍♀️
Did you know this difference? Tag a med student or friend who needs to see this! 👇
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What to avoid when taking Chlorthalidone? #chlorthalidone #hypertension #heartfailure

In this video it is described that
Warnings
You should not use chlorthalidone if you are unable to urinate, or if you are allergic to sulfa drugs.
Before taking this medicine
You should not use chlorthalidone if you are allergic to it, or if:
• you are unable to urinate; or
• you are allergic to sulfa drugs.
Tell your doctor if you have ever had:
• kidney disease;
• heart failure;
• gout;
• high cholesterol or triglycerides;
• diabetes; or
• if you are on a low-salt diet.
Tell your doctor if you are pregnant or plan to become pregnant.
Taking chlorthalidone during pregnancy may cause side effects in the newborn baby, such as jaundice (yellowing of the skin or eyes), bruising or bleeding, low blood sugar, or an electrolyte imbalance.
Do not start or stop taking chlorthalidone during pregnancy without your doctor's advice.
Although chlorthalidone may cause side effects in a newborn, having high blood pressure during pregnancy can cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.
You should not breastfeed while using chlorthalidone.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking chlorthalidone. This can lead to very low blood pressure, a serious electrolyte imbalance, or kidney failure.
Your blood pressure will need to be checked often. Your blood and urine may both be tested if you have been vomiting or are dehydrated.
Chlorthalidone can affect the results of certain medical tests. Tell any doctor who treats you that you are using chlorthalidone.
Major Drug Interactions of Chlorthalidone
Allopurinol
Using allopurinol together with chlorthalidone can increase your risk of serious skin reactions.
Call your doctor immediately if you experience symptoms such as a rash, itching, fever, or chills.
If your doctor does prescribe these medications together, you may need a dose adjustment and closer monitoring to safely use both medications.
Amiodarone
Talk to your doctor before using amiodarone together with chlorthalidone. Combining these medications can increase the risk of an irregular heart rhythm that may be serious.
If your doctor prescribes these medications together, you may need regular monitoring of your electrolyte (magnesium, potassium) levels as well as other tests to safely use both medications.
You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with amiodarone.
In addition, you should let your doctor know if you experience signs of electrolyte disturbance such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting.
Cisapride
Using cisapride together with chlorthalidone is not recommended. Combining these medications can increase the risk of an irregular heart rhythm that may be serious.
You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with cisapride.
Lithium
Ask your doctor before using chlorthalidone and lithium. Using chlorthalidone together with lithium can increase the effects of lithium. This may cause diarrhea, vomiting, drowsiness, tremor, thirst, increased urination, lack of coordination, or muscle weakness.
You may need a dose adjustment or special test to safely use both medications.
Sodium Nitrite
When use of sodium nitrite is required, the doctor should be told if you have been receiving treatment with chlorthalidone. Sodium nitrite can cause hypotension (low blood pressure), and the risk may be greater when combined with other medications that decrease blood pressure such as chlorthalidone.
Excessively low blood pressure can lead to shock, collapse, coma, or even death. Your doctor will need to monitor you closely and possibly take extra precautions for you to safely use these medications together.
Tizanidine
TiZANidine and chlorthalidone may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption.
Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome.

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INFORMATION ABOUT CHLORTHALIDONE
Chlorthalidone Uses
Chlorthalidone is used for Hypertension (high blood pressure) and Edema. It treats oedema (fluid overload) associated with heart, liver, kidney or lung disease.
How Chlorthalidone works
Chlorthalidone is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.
Common side effects of Chlorthalidone
Headache, Nausea, Vomiting, Dizziness, Vertigo, Orthostatic hypotension (sudden lowering of blood pressure on standing)
EXPERT ADVICE FOR CHLORTHALIDONE
Take it in the morning with breakfast to avoid getting up at night to urinate.
It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you.
Avoid alcohol intake while taking Chlorthalidone as it may increase the dizziness.
It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication.
Monitor your blood pressure after starting Chlorthalidone, and notify your doctor if it does not lower down.
Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
FREQUENTLY ASKED QUESTIONS FOR CHLORTHALIDONE
Chlorthalidone
Q. Can I drink alcohol while taking Chlorthalidone?
No, do not take alcohol while on treatment with Chlorthalidone. Taking alcohol with Chlorthalidone may lower your blood pressure suddenly making you feel dizzy and lightheaded.
Q. What happens if I take more than the recommended dose of Chlorthalidone?
If you take more than the prescribed dose of Chlorthalidone, you may experience nausea, lightheadedness, weakness, fast or irregular heart beat, sleepiness, muscle cramps and pain, difficulty in breathing. Taking this medicine in high doses may even cause a heart attack. In a situation like this, contact your doctor immediately or seek emergency help in a nearby hospital.
Q. Can I take ibuprofen with Chlorthalidone?
This combination is best avoided since the two medicines may interfere with each other. However, if your doctor advises you to take both ibuprofen and Chlorthalidone, you will need to keep a regular check on your blood pressure and also monitor your kidney function tests.
Q. Does Chlorthalidone increase uric acid? Can it cause gout?
Yes, Chlorthalidone may raise uric acid levels. However, the occurrence of gout due to Chlorthalidone is very rare.
Q. Does Chlorthalidone cause skin cancer?
No, there have been no reports of Chlorthalidone causing skin cancer. However, in rare cases, this medicine can make the skin more sensitive to sunlight than usual. If you are exposed to direct sunlight you may get skin rash, so wear protective clothing and use sunscreen.
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Thanks For Watching
Sandesh Verma

A review of data from the SHEP trial. This video discusses the importance of potassium levels in patients taking thiazide diuretics.

Chlorthalidone is a low ceiling diuretic that acts like thiazides and it is used in treatment of hypertension and edema. This drug blocks Na+/Cl- symport at the distal tubule.

Chlorthalidone is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

Video Content:
0:00 Chlorthalidone tablets
0:43 How to use
1:39 Contraindications
1:52 Precautions
2:38 Side Effects

Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor.

#Chlorthalidone #hypertension #medicine

Chlorthalidone Uses and Potential Side Effects #chlorthalidone25mg #sideeffectsofchlorthalidone25mg

In this video it is described that
Chlorthalidone is a medication primarily used to treat high blood pressure (hypertension) and edema (fluid retention). It belongs to a class of drugs known as thiazide diuretics. Chlorthalidone works by increasing the excretion of sodium and water from the body, which helps to lower blood pressure and reduce fluid buildup.
Uses:
1. Hypertension: Chlorthalidone is commonly prescribed to lower blood pressure. By reducing the amount of fluid in the bloodstream and relaxing blood vessels, it helps to decrease the overall pressure against the artery walls.
2. Edema: Chlorthalidone can also be used to treat edema, which is the accumulation of excess fluid in the body's tissues. It helps the body eliminate excess salt and water through urine, which reduces swelling.
Side Effects: Like all medications, chlorthalidone can have potential side effects. Not everyone will experience these side effects, and some may experience them to a greater degree than others. Common side effects of chlorthalidone may include:
1. Dehydration: Since chlorthalidone increases urine output, it can lead to dehydration if you don't consume enough fluids.
2. Electrolyte Imbalance: This medication can lead to imbalances in electrolytes like potassium, sodium, and magnesium. This might result in symptoms such as muscle cramps, weakness, or irregular heartbeats.
3. Dizziness or Lightheadedness: Chlorthalidone can cause a drop in blood pressure, which may lead to dizziness or lightheadedness, especially when standing up quickly.
4. Increased Urination: Due to its diuretic effect, chlorthalidone can increase the frequency of urination.
5. Sensitivity to Sunlight: Some people may become more sensitive to sunlight while taking chlorthalidone, leading to an increased risk of sunburn.
6. Gout Attacks: Thiazide diuretics like chlorthalidone can sometimes trigger gout attacks in individuals who are prone to this condition.
7. Elevated Blood Sugar Levels: Chlorthalidone may lead to a slight increase in blood sugar levels, which could be problematic for individuals with diabetes.
8. Sexual Dysfunction: In some cases, thiazide diuretics like chlorthalidone may contribute to sexual dysfunction.
It's important to note that this is not an exhaustive list of side effects, and some individuals may experience rare or severe reactions. If you're prescribed chlorthalidone and experience any concerning or unusual symptoms, it's important to contact your healthcare provider for guidance.

Welcome to our educational video by Dr. Lukasz Kiljanek, a Board Certified Nephrologist, Hypertension Specialist, and Internal Medicine physician.

Chlorthalidone (also sold under the registered brand names Hygroton and Thalitone) is one of the most commonly prescribed medications, water pills or diuretics used for treating hypertension (high blood pressures) and edema (swelling) associated with heart failure, kidney disease. Here are some common side effects and important information to keep in mind:

Frequent Urination: Chlorthalidone works by causing your kidneys to remove excess fluid from your body, which leads to increased urination. While this can be inconvenient, it is often a desired effect to help get rid of excess fluid in conditions like heart failure or edema.

Dizziness: Dizziness can happen, especially if you stand up too quickly. This is because Chlorthalidone can lower your blood pressure, especially if the dose is too strong, or if you have other problems making you dehydrated, like diarrhea or vomiting. Dehydration can add to its effect and make the dizziness worse.

Electrolyte Imbalance: Chlorthalidone can cause your electrolyte levels (such as potassium and sodium) to drop. Your healthcare provider will likely monitor your electrolyte levels through blood work, usually a few weeks after starting or increasing the dose, to ensure they remain within safe ranges.

Dehydration: Because Chlorthalidone increases urination, it can lead to dehydration. Symptoms of dehydration include dry mouth, excessive thirst, dizziness, and reduced urine output.

Hearing Issues: Although rare, some people might experience ringing in the ears (tinnitus) or hearing loss. If you notice any hearing issues, notify your healthcare provider immediately.

Monitoring Blood Work: It is important to monitor your creatinine, potassium, and sodium levels through blood work, which can range from days to weeks after the initiation of Chlorthalidone or after an increased dose. The timing of these checks will depend on the dose and your personal sensitivity to the medication.

Always notify your healthcare provider if you develop any side effects or have any concerns or questions about your medication. They can provide the best advice and support for your specific situation.

Disclaimer:
This video is for educational purposes only. Do not change your medications or therapy without talking to your healthcare provider.