Paxlovid Side Effects


New drugs approved to treat COVID-19 may pose a risk depending on what other medications patients are taking. Nicole Fierro reports.
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Health Minister Khairy Jamaluddin said the Paxlovid antiviral medicine used on 4,001 Covid-19 patients showed no serious side effects.
He said this during a press conference on Friday (July 8) that Covid-19 patients who displayed slight to medium infection severity levels can visit Covid-19 Assesment Centres to receive the medication.
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What Are The Side Effects Of Nirmatrelvir/Ritonavir (Paxlovid)? In this informative video, we will discuss the side effects associated with Nirmatrelvir/Ritonavir, commonly referred to as Paxlovid. This medication is used for treating COVID-19 and combines two active ingredients that work together to combat the virus. While many individuals may find relief from COVID-19 symptoms with Paxlovid, it is essential to be aware of the potential side effects that may arise during treatment.
We will cover both the common side effects that many users experience, such as alterations in taste, diarrhea, headaches, nausea, and stomach pain, as well as more serious reactions that, although less frequent, can occur. Understanding these side effects is vital for anyone considering or currently taking this medication. We will also touch on the importance of discussing any other medications you may be taking with your healthcare provider to avoid possible drug interactions.
If you are currently using Paxlovid or considering it as a treatment option, this video will provide you with essential information to help you navigate your treatment safely. Don't forget to consult your healthcare provider if you experience any side effects or have questions about your treatment plan.
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#Paxlovid #Nirmatrelvir #Ritonavir #COVID19Treatment #SideEffects #MedicationSafety #DrugInteractions #Healthcare #PatientCare #Pharmaceuticals #COVID19 #HealthAwareness #Medications #TreatmentOptions #PublicHealth #Wellness
About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.


Mel reviews the newest antiviral for COVID "Ritonavir" PAXLOVID.
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PHARMACIST Fi shares how you and your doctor, together, can try to avoid medicine interactions between Paxlovid and some other medicines, herbal medicines, vitamin & mineral products, & supplements.
While PHARMACIST Fi shares general ways to try to avoid Paxlovid medicine interactions in this video, she is currently making another video which looks at quite a few specific Paxlovid interactions to avoid - so stay tuned for that!
PHARMACIST Fi is also making a video about how to take Paxlovid - because it needs to be taken a very particular way to work well.
Here is the link to the PHARMACIST Fi video about CMIs (a CMI is a 'Consumer Medicine Information' document, which is called a 'Medication Guide' in the U.S.A., or a 'Patient Information Leaflet' in the U.K.; each medicine has a CMI, which either comes with the medicine or can be printed or emailed to you by a pharmacist or doctor):
https://www.youtube.com/watch?v=79CF6A5ZZ3I
&
here is the link to the PHARMACIST Fi video about making a
Medicines, Allergies & Contacts List:
https://www.youtube.com/watch?v=6gveHPwmc9s
&
here is a link to the free NPS MedicineWise App, which you are welcome to use to help you make a Medicines, Allergies & Contacts List:
https://www.nps.org.au/medicinewiseapp
Here is a link to the Australian Paxlovid CMI created June 2022 (which is the current version for July 2022) - but ask your pharmacist for the latest CMI if Paxlovid is ever prescribed for you, in case the CMI gets changed before then:
https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2022-CMI-01050-1&d=20220812172310101
While PHARMACIST Fi mentions in this video that the manufacturer of Paxlovid currently advises you not to use Paxlovid if you are breastfeeding or pregnant, here is some further info on these topics....
The current (July 2022) CMI for Paxlovid also more specifically advises:
"You should not breast-feed your baby while taking PAXLOVID and for 7 days after stopping treatment."
Because Paxlovid's manufacturer currently (July 2022) advises against taking Paxlovid if you are pregnant, they also advise in the current (July 2022) Australian Paxlovid CMI that:
"Women of child-bearing potential should be on an effective contraceptive method before starting treatment and for 7 days after stopping treatment" with Paxlovid.
Another option would be to not have sex during Paxlovid treatment and also not have sex until it is more than 7 days after you stopped Paxlovid treatment.
During Paxlovid treatment and also for one month after stopping treatment, Paxlovid might reduce effectiveness of many common types of birth control pills, and some hormonal devices like the vaginal ring (combined contraceptives which contain ethinylestradiol; this may be written as ethinyl estradiol in some countries) - so if this may apply to you, watch Top Tip #10 in this video, and ask your doctor to help you decide which of the 3 options may be best for you.
If you would like more in-depth scientific info about Paxlovid, here is a link to the Australian Paxlovid Product Information (revised 20 July 2022, and current in July 2022) - but remember to ask your pharmacist for the latest product information if you ever need Paxlovid - in case the info in this document may be changed due to new research in the coming months or years:
https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2022-PI-01049-1
The rules around who is eligible for Paxlovid may vary between countries and over time (for example, Australian rules just changed recently), but the general overall theme expressed in the Australian CMI July 2022 is that Paxlovid is currently "used to treat COVID-19 in adults who are at increased risk of hospitalization or death", and Paxlovid Product Information July 2022 states it "should be taken as soon as possible after a diagnosis of COVID-19 has been made and within 5 days symptoms onset".
Your doctor and pharmacist will have access to the eligibility criteria in your country, which might change over time (for example: due to new research findings).
Here is a link to a PHARMACIST Fi video about medicine interactions (this video has general info and is not specific to Paxlovid), in case it may also be of interest to you:
https://www.youtube.com/watch?v=ckRihqtel-4
We hope this info has been helpful for you!
Please also see the disclaimer at the end of this video.
If you would like to support PHARMACIST Fi to produce more Medicine Safety videos, please consider making a purchase from her Official Store at: https://pharmacist-fi.myshopif....y.com/collections/al , or making a paypal donation to PHARMACIST Fi at https://www.pharmacistfi.com/donate


Infectious disease expert Dr. Isaac Bogoch says the antiviral pill Paxlovid is for the 'highest of high risk' for COVID-19 hospitalization.
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Chris Hayes: If we're going to let Covid circulate relatively unchecked, then we need to be putting our backs into the effort to develop the next generation of vaccines and drugs and getting the ones we have, like Paxlovid, to everyone who needs and wants it.
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#MSNBC #Covid #Paxlovid


9NEWS Medical Expert Dr. Payal Kohli discusses what Paxlovid is and how it works to treat COVID-19.
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Roger Seheult, MD of MedCram illustrates how the Pfizer coronavirus pill called Paxlovid works, its efficacy, and its side effects. See all Dr. Seheult's videos at: https://www.medcram.com/?utm_source=Youtube&utm_medium=Video&utm_campaign=Video+Link+Clicks&utm_term=Pfizer+COVID+19+FDA+Authorized+Pill+%22Paxlovid%22+Explained&utm_content=GMMTw0MAT-8
Clinical trial data for Paxlovid show that if taken within 3 days of symptom onset, hospitalizations and death were reduced by 89% compared to placebo.
(This is Update 144 in The MedCram Coronavirus video series. It was recorded on December 29, 2021)
Roger Seheult, MD is the co-founder and lead professor at https://www.medcram.com/?utm_source=Youtube&utm_medium=Video&utm_campaign=Video+Link+Clicks&utm_term=Pfizer+COVID+19+FDA+Authorized+Pill+%22Paxlovid%22+Explained&utm_content=GMMTw0MAT-8
He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.
LINKS / REFERENCES:
Pfizer Announces Additional Phase 2/3 Study Results (Pfizer) | https://www.pfizer.com/news/pr....ess-release/press-re
Pfizer’s Novel COVID-19 Oral Antiviral Treatment Candidate (Pfizer) | https://www.pfizer.com/news/pr....ess-release/press-re
How Pfizer's New Drug Fights COVID [PAXLOVID] (Simplifying Synthesis) | https://youtu.be/HHzaiAwJpfQ
The SARS-CoV-2 main protease as drug target (PMC) | https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC73315
Covid-19: Pfizer’s antiviral Paxlovid effective against severe disease and Omicron variant (Pharmaceutical Technology) | https://www.pharmaceutical-tec....hnology.com/special-
All coronavirus updates are at MedCram.com (including more discussion on new COVID variants, fluvoxamine, Pfizer covid pill, and more).
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#COVID19 #Omicron #Coronavirus


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Price of COVID-19 medicine rises
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Paxlovid, it this an evidence based intervention in May 2022?
Paper FDA EMU was based on
https://www.nejm.org/doi/full/....10.1056/NEJMoa211854
EPIC-HR (Evaluation of Protease Inhibition for COVID-19 in High-Risk Patients)
1120 patients received nirmatrelvir plus ritonavir
1126 received placebo
Relative risk reduction
Risk of progression to severe Covid-19, 89% lower than the risk with placebo
Absolute risk reduction
https://www.precisionvaccinati....ons.com/what-paxlovi
7% down to 1%
symptomatic, unvaccinated, non hospitalized adults
at high risk for progression to severe coronavirus disease 2019
July 16 and December 9, 2021
If vaccinated people and previously infected people are partly protected
More people would need to be treated to prevent one adverse event
Pfizer press release (5th November 2021)
https://www.pfizer.com/news/pr....ess-release/press-re
our oral antiviral candidate, … has the potential to save patients’ lives,
reduce the severity of COVID-19 infections,
and eliminate up to nine out of ten hospitalizations
Pfizer Shares In Vitro Efficacy of Novel COVID-19 Oral Treatment Against Omicron Variant
https://www.pfizer.com/news/pr....ess-release/press-re
https://www.yalemedicine.org/n....ews/12-things-to-kno
https://www.fda.gov/media/155051/download
The results showed in all cases that nirmatrelvir was a potent inhibitor of its target.
PAXLOVID™ for Post-Exposure Prophylactic Use
https://www.pfizer.com/news/pr....ess-release/press-re
Evaluated data from 2,957 adults
Pfizer observed risk reductions of 32% (5 day course)
37% reduction (10 day course)
These results, however, were not statistically significant and, as such, the primary endpoint of reducing the risk of confirmed and symptomatic COVID-19 infection in adults who had been exposed to the virus through a household contact was not met.
FACT SHEET FOR PATIENTS, PARENTS, AND CAREGIVERS
EMERGENCY USE AUTHORIZATION (EUA) OF PAXLOVID FOR CORONAVIRUS DISEASE 2019 (COVID-19)
https://www.fda.gov/media/155051/download
PAXLOVID is not an FDA-approved medicine in the United States.
PAXLOVID is an investigational medicine
Some medicines may interact with PAXLOVID and may cause serious side effects.
If you take too much PAXLOVID, call your healthcare provider or go to the nearest hospital emergency room right away.
Possible side effects of PAXLOVID are:
Allergic Reactions
trouble swallowing or breathing, swelling of the mouth, lips, or face, throat tightness, hoarseness, skin rash
Liver Problems. Tell your healthcare provider right away,
loss of appetite, yellowing of your skin and the whites of eyes (jaundice), dark-colored urine, pale colored stools and itchy skin, stomach area (abdominal) pain.
Other possible side effects include:
altered sense of taste, diarrhea, high blood pressure, muscle aches
Dr. Ashish K. Jha, White House, Covid-19 coordinator
The new White House Covid czar says avoiding all virus infections isn’t the goal of U.S. pandemic policy.
Paxlovid, push to reach the vulnerable
Doctors are too hesitant to prescribe the drug
https://en.wikipedia.org/wiki/Ashish_Jha
Senior Advisor at Albright Stonebridge Group
https://www.politico.com/newsl....etters/transition-pl
The firm advises clients on international policy and global markets
Patrick Vallance
From 2012 to 2018, he was President of Research and Development at global pharmaceutical company, GlaxoSmithKline (GSK)
https://www.telegraph.co.uk/ne....ws/2020/09/23/reveal
Cashed £5,000,000 GSK shares
Future jobs of FDA’s haematology-oncology reviewers
https://www.bmj.com/content/354/bmj.i5055.full
https://www.npr.org/sections/h....ealth-shots/2016/09/
More than a quarter of the Food and Drug Administration employees
(who approved cancer and hematology drugs from 2001 through 2010)
left the agency and now work or consult for pharmaceutical companies,


Hi there! I’m Pharmacist Michael, here to help you live a happy and healthy life. In today’s video, we’re diving into Paxlovid, the antiviral medication making waves as an effective treatment for COVID-19. But is it right for you? When should you consider taking it, and what should you know about potential side effects, drug interactions, and contraindications? Let’s break it all down!
📌 Key Topics Covered:
What is Paxlovid? How it works to treat COVID-19
Who should take Paxlovid? High-risk groups and the importance of early treatment
Potential side effects: Metallic taste, nausea, diarrhea, and more
Drug interactions: Why a full medication review is crucial
Who should avoid Paxlovid? Key precautions and contraindications
💡 Why Watch?
Learn whether Paxlovid is right for you or your loved ones
Understand its benefits and risks to make an informed decision
Get practical tips to manage side effects and ensure effective use
⏰ Don’t Miss These Important Points:
Paxlovid is most effective within the first 5 days of symptom onset
It’s designed for people with mild to moderate symptoms who are at high risk of severe COVID-19
Not suitable for those with severe kidney or liver disease, certain drug interactions, or specific conditions like pregnancy
🔔 Subscribe for more pharmacist-approved health tips to stay informed and healthy!
Need more info? Drop your questions in the comments—I’m here to help!
Stay safe, stay healthy, and remember: prevention and early treatment save lives.
Pharmacist Michael
Happy, Healthy Living
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This video cannot and does not contain medical/health advice. The medical/health information is provided for general informational and educational purposes only and is not a substitute for professional advice. Accordingly, before taking any actions based upon such information, we encourage you to consult with the appropriate professionals. We do not provide any kind of medical health advice. THE USE OR RELIANCE OF ANY INFORMATION CONTAINED IN THIS VIDEO IS SOLELY AT YOUR OWN RISK.


Paxlovid - What Prescribers and Pharmacists Need to Know:
(INCLUDES LIST OF DRUG INTERACTIONS):
https://covid19-sciencetable.c....a/sciencebrief/nirma
EPIC-HR Study:
https://www.nejm.org/doi/full/....10.1056/nejmoa211854
Timestamps:
0:00 Introduction
0:07 What is Paxlovid?
0:31 Who Can Benefit from Paxlovid?
0:56 Dose/Treatment Course of Paxlovid
1:15 Side Effects
1:39 Drug Interactions
2:12 Outro


People taking the anti-viral medication Paxlovid for COVID-19 are reporting an awful, metallic taste that just won't go away. Patients have nicknamed the side effect "Paxlovid Mouth."
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What is Paxlovid and what is it like? Hear from cancer survivor (non-Hodgkin lymphoma) Stephanie Chuang, also founder of The Patient Story, on the experience from the onset of COVID-19 symptoms, testing positive, to the first dose of Paxlovid.
We’ll be updating the experience through the end, including whether Stephanie experiences the newly reported “Paxlovid Rebound,” where symptoms may be coming back even after the full course of treatment.
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____________________________
#ThePatientStory #covidpositive #Paxlovid #Cancerstories #Cancerpatients #cancersurvivors


This video looks at the new anti COVID-19 Paxlovid uses and side effects.It looks and how it works and how it is taken.
Read latest Think your Health: Well being : https://drthinkyourhealth.com/blog/
Read entire transcript here: https://drthinkyourhealth.com/....paxlovid-uses-and-si
⏰TIMESTAMPS:
00:00 Intro
00:25 What is Paxlovid ?
00:53 Who can use this drug?
01:07 How does Paxlovid work?
02:42 When to take Paxlovid?
02:52 Which individuals are at a higher risk for developing severe COVID-19?
03:29. Paxlovid side effects?
04:26 Drug-drug interactions
04:47 Advice for older adults
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Sources:
1)https://www.fda.gov/media/155050/download
2)https://www.fda.gov/media/155051/download
3)https://emergency.cdc.gov/coca..../ppt/2022/011222_sli
4)https://www.covid19oralrx-patient.com/side-effects
5)https://www.covid19oralrx-pati....ent.com/files/Clean_
Think Your Health provides general educational information on various topics on this YouTube video and channel as a public service, which should not be construed as medical, psychological or health advice. These are my personal opinions only.
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#Paxlovid


Dr. Christy explains two phenomenon that we are seeing with Paxlovid treatment and the information we know about it.
REFERENCES:
CDC Advisory:
https://emergency.cdc.gov/han/....2022/pdf/CDC_HAN_467
VA Study:
https://www.researchsquare.com..../article/rs-1588371/