Paxlovid Side Effects

Colorado doctors warn about drug interactions with new COVID-19 treatment pills
Colorado doctors warn about drug interactions with new COVID-19 treatment pills Side Effects 0 Views • 16 days ago

New drugs approved to treat COVID-19 may pose a risk depending on what other medications patients are taking. Nicole Fierro reports.

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What Are The Side Effects Of Nirmatrelvir/Ritonavir (Paxlovid)? - Pharmaceutical Insights
What Are The Side Effects Of Nirmatrelvir/Ritonavir (Paxlovid)? - Pharmaceutical Insights Side Effects 0 Views • 16 days ago

What Are The Side Effects Of Nirmatrelvir/Ritonavir (Paxlovid)? In this informative video, we will discuss the side effects associated with Nirmatrelvir/Ritonavir, commonly referred to as Paxlovid. This medication is used for treating COVID-19 and combines two active ingredients that work together to combat the virus. While many individuals may find relief from COVID-19 symptoms with Paxlovid, it is essential to be aware of the potential side effects that may arise during treatment.

We will cover both the common side effects that many users experience, such as alterations in taste, diarrhea, headaches, nausea, and stomach pain, as well as more serious reactions that, although less frequent, can occur. Understanding these side effects is vital for anyone considering or currently taking this medication. We will also touch on the importance of discussing any other medications you may be taking with your healthcare provider to avoid possible drug interactions.

If you are currently using Paxlovid or considering it as a treatment option, this video will provide you with essential information to help you navigate your treatment safely. Don't forget to consult your healthcare provider if you experience any side effects or have questions about your treatment plan.

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#Paxlovid #Nirmatrelvir #Ritonavir #COVID19Treatment #SideEffects #MedicationSafety #DrugInteractions #Healthcare #PatientCare #Pharmaceuticals #COVID19 #HealthAwareness #Medications #TreatmentOptions #PublicHealth #Wellness

About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

PAXLOVID for COVID-19 (Part 1 - Main Video) - 'Some Need-to-Know Info!' - PHARMACIST Fi
PAXLOVID for COVID-19 (Part 1 - Main Video) - 'Some Need-to-Know Info!' - PHARMACIST Fi Side Effects 0 Views • 16 days ago

PHARMACIST Fi shares how you and your doctor, together, can try to avoid medicine interactions between Paxlovid and some other medicines, herbal medicines, vitamin & mineral products, & supplements.

While PHARMACIST Fi shares general ways to try to avoid Paxlovid medicine interactions in this video, she is currently making another video which looks at quite a few specific Paxlovid interactions to avoid - so stay tuned for that!

PHARMACIST Fi is also making a video about how to take Paxlovid - because it needs to be taken a very particular way to work well.

Here is the link to the PHARMACIST Fi video about CMIs (a CMI is a 'Consumer Medicine Information' document, which is called a 'Medication Guide' in the U.S.A., or a 'Patient Information Leaflet' in the U.K.; each medicine has a CMI, which either comes with the medicine or can be printed or emailed to you by a pharmacist or doctor):
https://www.youtube.com/watch?v=79CF6A5ZZ3I
&
here is the link to the PHARMACIST Fi video about making a
Medicines, Allergies & Contacts List:
https://www.youtube.com/watch?v=6gveHPwmc9s
&
here is a link to the free NPS MedicineWise App, which you are welcome to use to help you make a Medicines, Allergies & Contacts List:
https://www.nps.org.au/medicinewiseapp

Here is a link to the Australian Paxlovid CMI created June 2022 (which is the current version for July 2022) - but ask your pharmacist for the latest CMI if Paxlovid is ever prescribed for you, in case the CMI gets changed before then:
https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2022-CMI-01050-1&d=20220812172310101

While PHARMACIST Fi mentions in this video that the manufacturer of Paxlovid currently advises you not to use Paxlovid if you are breastfeeding or pregnant, here is some further info on these topics....

The current (July 2022) CMI for Paxlovid also more specifically advises:
"You should not breast-feed your baby while taking PAXLOVID and for 7 days after stopping treatment."

Because Paxlovid's manufacturer currently (July 2022) advises against taking Paxlovid if you are pregnant, they also advise in the current (July 2022) Australian Paxlovid CMI that:
"Women of child-bearing potential should be on an effective contraceptive method before starting treatment and for 7 days after stopping treatment" with Paxlovid.
Another option would be to not have sex during Paxlovid treatment and also not have sex until it is more than 7 days after you stopped Paxlovid treatment.

During Paxlovid treatment and also for one month after stopping treatment, Paxlovid might reduce effectiveness of many common types of birth control pills, and some hormonal devices like the vaginal ring (combined contraceptives which contain ethinylestradiol; this may be written as ethinyl estradiol in some countries) - so if this may apply to you, watch Top Tip #10 in this video, and ask your doctor to help you decide which of the 3 options may be best for you.

If you would like more in-depth scientific info about Paxlovid, here is a link to the Australian Paxlovid Product Information (revised 20 July 2022, and current in July 2022) - but remember to ask your pharmacist for the latest product information if you ever need Paxlovid - in case the info in this document may be changed due to new research in the coming months or years:
https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2022-PI-01049-1

The rules around who is eligible for Paxlovid may vary between countries and over time (for example, Australian rules just changed recently), but the general overall theme expressed in the Australian CMI July 2022 is that Paxlovid is currently "used to treat COVID-19 in adults who are at increased risk of hospitalization or death", and Paxlovid Product Information July 2022 states it "should be taken as soon as possible after a diagnosis of COVID-19 has been made and within 5 days symptoms onset".
Your doctor and pharmacist will have access to the eligibility criteria in your country, which might change over time (for example: due to new research findings).

Here is a link to a PHARMACIST Fi video about medicine interactions (this video has general info and is not specific to Paxlovid), in case it may also be of interest to you:
https://www.youtube.com/watch?v=ckRihqtel-4

We hope this info has been helpful for you!
Please also see the disclaimer at the end of this video.
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What to know before seeking out a Paxlovid prescription
What to know before seeking out a Paxlovid prescription Side Effects 0 Views • 16 days ago

Infectious disease expert Dr. Isaac Bogoch says the antiviral pill Paxlovid is for the 'highest of high risk' for COVID-19 hospitalization.

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Chris Hayes On Taking Paxlovid And What He Learned From His Covid Experience
Chris Hayes On Taking Paxlovid And What He Learned From His Covid Experience Side Effects 0 Views • 16 days ago

Chris Hayes: If we're going to let Covid circulate relatively unchecked, then we need to be putting our backs into the effort to develop the next generation of vaccines and drugs and getting the ones we have, like Paxlovid, to everyone who needs and wants it.
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#MSNBC #Covid #Paxlovid

Pfizer COVID 19 FDA Authorized Pill
Pfizer COVID 19 FDA Authorized Pill Side Effects 0 Views • 16 days ago

Roger Seheult, MD of MedCram illustrates how the Pfizer coronavirus pill called Paxlovid works, its efficacy, and its side effects. See all Dr. Seheult's videos at: https://www.medcram.com/?utm_source=Youtube&utm_medium=Video&utm_campaign=Video+Link+Clicks&utm_term=Pfizer+COVID+19+FDA+Authorized+Pill+%22Paxlovid%22+Explained&utm_content=GMMTw0MAT-8

Clinical trial data for Paxlovid show that if taken within 3 days of symptom onset, hospitalizations and death were reduced by 89% compared to placebo.

(This is Update 144 in The MedCram Coronavirus video series. It was recorded on December 29, 2021)

Roger Seheult, MD is the co-founder and lead professor at https://www.medcram.com/?utm_source=Youtube&utm_medium=Video&utm_campaign=Video+Link+Clicks&utm_term=Pfizer+COVID+19+FDA+Authorized+Pill+%22Paxlovid%22+Explained&utm_content=GMMTw0MAT-8

He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


LINKS / REFERENCES:

Pfizer Announces Additional Phase 2/3 Study Results (Pfizer) |
https://www.pfizer.com/news/pr....ess-release/press-re

Pfizer’s Novel COVID-19 Oral Antiviral Treatment Candidate (Pfizer) | https://www.pfizer.com/news/pr....ess-release/press-re

How Pfizer's New Drug Fights COVID [PAXLOVID] (Simplifying Synthesis) | https://youtu.be/HHzaiAwJpfQ

The SARS-CoV-2 main protease as drug target (PMC) | https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC73315

Covid-19: Pfizer’s antiviral Paxlovid effective against severe disease and Omicron variant (Pharmaceutical Technology) | https://www.pharmaceutical-tec....hnology.com/special-



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#COVID19 #Omicron #Coronavirus

Paxlovid, evidence base?
Paxlovid, evidence base? Side Effects 0 Views • 16 days ago

Paxlovid, it this an evidence based intervention in May 2022?

Paper FDA EMU was based on

https://www.nejm.org/doi/full/....10.1056/NEJMoa211854

EPIC-HR (Evaluation of Protease Inhibition for COVID-19 in High-Risk Patients)

1120 patients received nirmatrelvir plus ritonavir

1126 received placebo

Relative risk reduction

Risk of progression to severe Covid-19, 89% lower than the risk with placebo

Absolute risk reduction

https://www.precisionvaccinati....ons.com/what-paxlovi

7% down to 1%

symptomatic, unvaccinated, non hospitalized adults

at high risk for progression to severe coronavirus disease 2019

July 16 and December 9, 2021

If vaccinated people and previously infected people are partly protected

More people would need to be treated to prevent one adverse event

Pfizer press release (5th November 2021)

https://www.pfizer.com/news/pr....ess-release/press-re

our oral antiviral candidate, … has the potential to save patients’ lives,

reduce the severity of COVID-19 infections,

and eliminate up to nine out of ten hospitalizations

Pfizer Shares In Vitro Efficacy of Novel COVID-19 Oral Treatment Against Omicron Variant

https://www.pfizer.com/news/pr....ess-release/press-re

https://www.yalemedicine.org/n....ews/12-things-to-kno

https://www.fda.gov/media/155051/download

The results showed in all cases that nirmatrelvir was a potent inhibitor of its target.

PAXLOVID™ for Post-Exposure Prophylactic Use

https://www.pfizer.com/news/pr....ess-release/press-re

Evaluated data from 2,957 adults

Pfizer observed risk reductions of 32% (5 day course)

37% reduction (10 day course)

These results, however, were not statistically significant and, as such, the primary endpoint of reducing the risk of confirmed and symptomatic COVID-19 infection in adults who had been exposed to the virus through a household contact was not met.





FACT SHEET FOR PATIENTS, PARENTS, AND CAREGIVERS
EMERGENCY USE AUTHORIZATION (EUA) OF PAXLOVID FOR CORONAVIRUS DISEASE 2019 (COVID-19)

https://www.fda.gov/media/155051/download

PAXLOVID is not an FDA-approved medicine in the United States.

PAXLOVID is an investigational medicine

Some medicines may interact with PAXLOVID and may cause serious side effects.

If you take too much PAXLOVID, call your healthcare provider or go to the nearest hospital emergency room right away.

Possible side effects of PAXLOVID are:

Allergic Reactions

trouble swallowing or breathing, swelling of the mouth, lips, or face, throat tightness, hoarseness, skin rash

Liver Problems. Tell your healthcare provider right away,

loss of appetite, yellowing of your skin and the whites of eyes (jaundice), dark-colored urine, pale colored stools and itchy skin, stomach area (abdominal) pain.

Other possible side effects include:
altered sense of taste, diarrhea, high blood pressure, muscle aches

Dr. Ashish K. Jha, White House, Covid-19 coordinator

The new White House Covid czar says avoiding all virus infections isn’t the goal of U.S. pandemic policy.

Paxlovid, push to reach the vulnerable

Doctors are too hesitant to prescribe the drug

https://en.wikipedia.org/wiki/Ashish_Jha

Senior Advisor at Albright Stonebridge Group

https://www.politico.com/newsl....etters/transition-pl

The firm advises clients on international policy and global markets

Patrick Vallance

From 2012 to 2018, he was President of Research and Development at global pharmaceutical company, GlaxoSmithKline (GSK)

https://www.telegraph.co.uk/ne....ws/2020/09/23/reveal

Cashed £5,000,000 GSK shares

Future jobs of FDA’s haematology-oncology reviewers

https://www.bmj.com/content/354/bmj.i5055.full

https://www.npr.org/sections/h....ealth-shots/2016/09/

More than a quarter of the Food and Drug Administration employees

(who approved cancer and hematology drugs from 2001 through 2010)

left the agency and now work or consult for pharmaceutical companies,

Paxlovid  Pros, Cons, Side Effects, and Benefits
Paxlovid Pros, Cons, Side Effects, and Benefits Side Effects 1 Views • 16 days ago

Paxlovid has emerged as a promising antiviral treatment in the fight against COVID-19, particularly for individuals at risk of severe illness. This oral medication combines two drugs—Nirmatrelvir, which prevents the virus from replicating, and Ritonavir, which boosts its effectiveness. Paxlovid works by blocking a key enzyme the virus needs to multiply, reducing the severity of infection and helping the immune system regain control. It is most effective when taken within five days of symptom onset and can significantly lower the risk of hospitalization and death in high-risk individuals. Its pill form makes it convenient and easy to use at home compared to other treatments like infusions.

While Paxlovid is generally safe, some potential side effects include a metallic or bitter taste and possible drug interactions. Patients should inform their doctors about any medications they are taking to avoid complications. Though Paxlovid is a powerful tool, it’s not a substitute for vaccination and is primarily for high-risk individuals. There is also a chance of viral resistance developing over time, emphasizing the need for ongoing research.

If you test positive for COVID-19 and may be eligible for Paxlovid, consult your healthcare provider promptly to discuss your options. Stay updated with guidance from reputable sources like the CDC and make informed decisions to protect your health. Paxlovid is an important step forward in managing COVID-19 but should be used as part of a broader strategy, including vaccines, to combat the pandemic.

The fight against COVID-19 has seen significant progress, and one of the most promising developments is the emergence of antiviral treatments like Paxlovid. This oral medication, taken as a five-day course, offers a new line of defense against the virus, particularly for individuals at risk of developing severe illness. Paxlovid is actually a combination of two antiviral drugs Nirmatrelvir and Ritonavir. Nirmatrelvir is the main soldier targeting the virus's ability to replicate within our bodies. Ritonavir acts as a booster, ensuring that nirmatrelvir stays active longer and at higher levels. This dual-action mechanism makes Paxlovid a potent weapon in our arsenal against COVID-19. It represents a significant step forward in managing the virus and preventing its worst outcomes. To understand how Paxlovid works, imagine a lock and key. The virus needs a specific key, an enzyme called protese, to unlock its ability to make copies of itself. Paxlovid essentially jams this lock. Nirmatrelvir, the key component of Paxlovid, acts as a protese inhibitor. It binds to the protose enzyme, preventing the virus from replicating and spreading within the body. By stopping viral replication, Paxlovid helps the immune system gain control and reduces the severity of the infection. This targeted approach makes Paxlovid effective against different variants of the virus, making it a valuable tool in our ongoing fight against COVID-19. It's like cutting off the virus's supply lines, hindering its ability to spread and cause further damage. One of Paxlovid's greatest strengths lies in its effectiveness when taken early in the course of infection. Ideally treatment should begin within five days of symptom onset. This is when the virus is actively replicating and spreading within the body. Studies have shown that Paxlovid can significantly reduce the risk of hospitalization and death in high risk individuals when taken early. It can help prevent the virus from overwhelming the immune system, especially in those who are more vulnerable to severe illness. The oral administration of Paxlovid is another advantage. Unlike some other COVID-19 treatments that require intravenous infusions, Paxlovid can be taken at home with a simple pill regimen, making it more accessible and convenient for patients. Potential side effects to consider. While Paxlovid is generally safe and well tolerated, it's important to be aware of potential side effects. The most common side effect reported is dysgeusia, an altered sense of taste which is often described as a metallic or bitter taste in the mouth. Staying informed about COVID-19 and its treatments is essential. Keep up to date with the latest recommendations from reputable sources like the Centers for Disease Control and Prevention, CDC, and consult with your health care provider if you have any questions or concerns. Remember knowledge is power. By understanding the benefits and limitations of treatments like PaxLovid, we can make informed decisions about our health and contribute to the ongoing fight against this global pandemic. MD Searchlight. Be Your Own Advocate. you

#Paxlovid
#COVID19Treatment
#AntiviralMedication
#FightCOVID19
#StayInformed
#HighRiskCare
#PaxlovidEffectiveness
#COVIDPrevention
#HealthMatters
#ScienceAgainstCOVID

When Should You Consider Taking Paxlovid?
When Should You Consider Taking Paxlovid? Side Effects 0 Views • 16 days ago

Hi there! I’m Pharmacist Michael, here to help you live a happy and healthy life. In today’s video, we’re diving into Paxlovid, the antiviral medication making waves as an effective treatment for COVID-19. But is it right for you? When should you consider taking it, and what should you know about potential side effects, drug interactions, and contraindications? Let’s break it all down!

📌 Key Topics Covered:

What is Paxlovid? How it works to treat COVID-19
Who should take Paxlovid? High-risk groups and the importance of early treatment
Potential side effects: Metallic taste, nausea, diarrhea, and more
Drug interactions: Why a full medication review is crucial
Who should avoid Paxlovid? Key precautions and contraindications
💡 Why Watch?

Learn whether Paxlovid is right for you or your loved ones
Understand its benefits and risks to make an informed decision
Get practical tips to manage side effects and ensure effective use
⏰ Don’t Miss These Important Points:

Paxlovid is most effective within the first 5 days of symptom onset
It’s designed for people with mild to moderate symptoms who are at high risk of severe COVID-19
Not suitable for those with severe kidney or liver disease, certain drug interactions, or specific conditions like pregnancy
🔔 Subscribe for more pharmacist-approved health tips to stay informed and healthy!

Need more info? Drop your questions in the comments—I’m here to help!

Stay safe, stay healthy, and remember: prevention and early treatment save lives.

Pharmacist Michael
Happy, Healthy Living

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This video cannot and does not contain medical/health advice. The medical/health information is provided for general informational and educational purposes only and is not a substitute for professional advice. Accordingly, before taking any actions based upon such information, we encourage you to consult with the appropriate professionals. We do not provide any kind of medical health advice. THE USE OR RELIANCE OF ANY INFORMATION CONTAINED IN THIS VIDEO IS SOLELY AT YOUR OWN RISK.

Paxlovid uses and side effects
Paxlovid uses and side effects Side Effects 0 Views • 16 days ago

This video looks at the new anti COVID-19 Paxlovid uses and side effects.It looks and how it works and how it is taken.


Read latest Think your Health: Well being :
https://drthinkyourhealth.com/blog/

Read entire transcript here: https://drthinkyourhealth.com/....paxlovid-uses-and-si



⏰TIMESTAMPS:

00:00 Intro
00:25 What is Paxlovid ?
00:53 Who can use this drug?
01:07 How does Paxlovid work?
02:42 When to take Paxlovid?
02:52 Which individuals are at a higher risk for developing severe COVID-19?
03:29. Paxlovid side effects?
04:26 Drug-drug interactions
04:47 Advice for older adults




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Sources:

1)https://www.fda.gov/media/155050/download
2)https://www.fda.gov/media/155051/download
3)https://emergency.cdc.gov/coca..../ppt/2022/011222_sli
4)https://www.covid19oralrx-patient.com/side-effects
5)https://www.covid19oralrx-pati....ent.com/files/Clean_





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#Paxlovid