🎯 Piroxicam x Meloxicam – Qual escolher? Qual orientar no balcão?

💊 Ambos são anti-inflamatórios da classe dos oxicams, com ação forte e dose única diária. Mas têm diferenças importantes que impactam a orientação no balcão!

🔹 PIROXICAM
✔️ Muito potente e com ação prolongada (meia-vida de até 50h);
⚠️ Inibe COX-1 e COX-2 → maior risco de lesão gástrica (gastrite, úlcera, sangramento);
🚫 Uso prolongado ou em idosos exige cautela redobrada!
🕐 Início de ação mais lento.

🔹 MELOXICAM
✔️ Ação anti-inflamatória eficiente, com meia-vida de ~20h;
🛡️ Seletividade maior para COX-2 → mais seguro para o trato gastrointestinal;
👵 Boa escolha para idosos ou tratamentos mais longos;
⏱️ Começa a agir mais rápido.

Conhecer essas diferenças ajuda a orientar com segurança, entender os riscos e entregar uma recomendação mais técnica e confiante.

Quer ganhar a confiança do seu paciente no balcão da farmácia?
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O Meloxicam é um medicamento anti-inflamatório não esteroidal (AINE) amplamente utilizado no tratamento de condições dolorosas e inflamatórias, como a artrite reumatoide e a osteoartrite. Este vídeo abordará detalhadamente o mecanismo de ação, as indicações e a posologia do Meloxicam, fornecendo informações essenciais para pacientes e profissionais de saúde.

### Mecanismo de Ação

O Meloxicam atua inibindo a síntese de prostaglandinas, que são substâncias responsáveis por causar inflamação, dor e febre no corpo. Ele faz isso ao reduzir a atividade enzimática da ciclo-oxigenase (COX), especificamente a COX-2, que está mais diretamente envolvida nos processos inflamatórios, sem afetar significativamente a COX-1, minimizando assim os efeitos adversos gastrointestinais associados a outros AINEs.

### Indicações

Este medicamento é indicado para o tratamento sintomático da artrite reumatoide e osteoartrites dolorosas, também conhecidas como artroses ou doenças degenerativas das articulações. O Meloxicam ajuda a aliviar a dor e a inflamação associadas a essas condições, melhorando a qualidade de vida dos pacientes.

### Posologia

A posologia do Meloxicam deve ser ajustada individualmente, considerando a gravidade da condição e a resposta do paciente ao tratamento. A dose inicial recomendada para adultos é de 7,5 mg uma vez ao dia, podendo ser aumentada para 15 mg por dia em pacientes que necessitam de uma analgesia adicional. A dose diária máxima recomendada é de 15 mg. Para adolescentes de 12 a 18 anos, a dose máxima diária recomendada é de 0,25 mg/kg, não excedendo 15 mg.

É importante ressaltar que o Meloxicam deve ser administrado com água ou outro líquido, juntamente com alimentos, para minimizar possíveis desconfortos gastrointestinais. Em pacientes com insuficiência renal leve ou moderada, não é necessária a redução da dose. No entanto, o Meloxicam é contraindicado em pacientes não dialisados com insuficiência renal grave.

### Considerações Finais

O Meloxicam é uma opção eficaz no tratamento de condições inflamatórias e dolorosas, como a artrite reumatoide e a osteoartrite. Seu mecanismo de ação específico permite um alívio efetivo da dor e da inflamação com um perfil de efeitos adversos potencialmente mais favorável em comparação com outros AINEs. No entanto, como qualquer medicamento, é fundamental seguir as orientações de dosagem e considerar as contraindicações e precauções para garantir o uso seguro e eficaz do Meloxicam.

[00:00] Introdução: Meloxicam como anti-inflamatório.
[00:30] Meloxicam: O que é e como funciona.
[01:30] Precauções e cuidados ao usar Meloxicam.
[02:18] Dosagem e efeitos do Meloxicam.
[02:48] Tempo para funcionar e duração do efeito.
[03:14] Contraindicações e efeitos adversos.
[03:41] Uso durante gravidez e amamentação.
[04:11] Benefícios e potência do Meloxicam.
[04:39] Segurança ao dirigir após o uso.
[05:15] Conclusão: Uso responsável do Meloxicam.

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#MSPFarmacología 💊 ¿Qué es el #meloxicam y cómo alivia la inflamación y fiebre? En condiciones crónicas como la artritis, este medicamento se toma de forma regular para mantener el control del dolor. ¡Aquí te contamos cómo funciona, comparte!

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No, meloxicam and naproxen are not the same medications. While both meloxicam and naproxen belong to the same class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs), they have some important differences.
Mechanism of Action: Meloxicam and naproxen work by inhibiting the production of certain enzymes called cyclooxygenases (COX). Meloxicam primarily inhibits COX-2, which is responsible for inflammation and pain, while naproxen inhibits both COX-1 and COX-2 enzymes.


Duration of Action: Meloxicam has a longer half-life compared to naproxen, which means it stays active in the body for a longer period of time. This allows for less frequent dosing of meloxicam, usually once daily, while naproxen is typically taken multiple times a day.


Prescribed Uses: Meloxicam is commonly prescribed to relieve pain and inflammation associated with conditions like osteoarthritis and rheumatoid arthritis. Naproxen is also used for the same conditions, but it is also prescribed for other types of pain, such as menstrual cramps and headaches.


Side Effects: Both meloxicam and naproxen can cause similar side effects, including stomach upset, heartburn, and increased risk of gastrointestinal bleeding. However, meloxicam has been associated with a higher risk of cardiovascular events, such as heart attack and stroke, compared to naproxen.


It is important to note that both meloxicam and naproxen are prescription medications, and you should always consult with a healthcare professional before starting or changing any medication regimen.

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¿Qué es el MELOXICAM y para qué sirve? ¿Cómo y cuándo tomar MELOXICAM? Mecanismo de acción y efectos secundarios del MELOXICAM.

No, meloxicam and Mobic are not the same thing, but they are closely related.
Meloxicam is the generic name of a nonsteroidal anti-inflammatory drug (NSAID) often used to alleviate pain and reduce inflammation associated with conditions such as arthritis and other musculoskeletal disorders. It works by inhibiting the production of certain chemicals in the body that cause pain and inflammation.
On the other hand, Mobic is a brand name for a specific formulation of meloxicam. It is produced and marketed by a pharmaceutical company. Mobic contains the same active ingredient as the generic meloxicam, but it may have different inactive ingredients or a different formulation that affects how the medication is released or absorbed by the body.
While both meloxicam and Mobic have the same therapeutic effect, they may differ in terms of pricing, availability, and specific brand-related factors. Some individuals may prefer to use the brand name Mobic due to factors such as brand loyalty, doctor's recommendations, or personal preferences. However, it's important to note that the generic meloxicam is usually more affordable and widely available.
Here is an example to better illustrate the difference: Let's say a patient visits their doctor for arthritis pain relief. The doctor may prescribe either meloxicam or Mobic depending on various factors such as the patient's medical history, preferences, and insurance coverage. If the patient's insurance does not cover brand name medications, they may opt for the generic meloxicam instead.
In summary, meloxicam and Mobic are related in that Mobic is a brand name for a specific formulation of meloxicam. While they have the same therapeutic effect, there may be differences in pricing, availability, and personal preferences that influence an individual's choice between the generic meloxicam and the brand name Mobic.

- Disclaimer:
The content provided on DrugFAQ Channel is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard on this channel.

DrugFAQ Channel does not endorse or recommend any specific drug, treatment, or medical procedure. The information presented here is based on general knowledge and may not be applicable to your individual health circumstances. Reliance on any information provided by DrugFAQ Channel is solely at your own risk.

We strive to provide accurate and up-to-date information, but the field of medicine is constantly evolving, and new research may change the understanding of certain aspects. DrugFAQ Channel shall not be responsible or liable for any errors, omissions, or inaccuracies in the content or for any reliance placed on the information provided.

By accessing and using DrugFAQ Channel, you agree to the terms of this disclaimer.

Meloxicam Vs Other Painkillers: A Comprehensive Comparison • Discover the truth about meloxicam and other painkillers in this comprehensive comparison video! Find out how meloxicam measures up against other NSAIDs and opioid painkillers, and learn about the risks and side effects associated with its use. Don't miss out on this essential information for effective pain management!

00:00 • How strong is meloxicam compared to other painkillers?
00:29 • What is Meloxicam?
00:54 • How Does Meloxicam Compare to Other NSAIDs?
01:30 • How Does Meloxicam Compare to Opioid Painkillers?
01:56 • Are there Risks and Side Effects with Meloxicam?

Mobic or Meloxicam is an NSAID just like Celebrex, ibuprofen and naproxen. Although it is classified as a non-specific inhibitor of the COX enzymes, at typical doses it basically blocks only the COX 2 enzyme. As such, Mobic should avoid many of the gastrointestinal, cardiovascular and thromboitc side effects of those aspirin relatives indiscriminately blocking both of the enzymes.

Mobic is the 38th most frequently prescribed medicine in America with more than 19 million prescriptions written each year. Mobic was patented in 1977 and was granted marketing approval by the FDA in 2000.

Primary indications are osteoarthritis, rheumatoid arthritis and juvenile rheumatoid arthritis. It is available as a tablet – either 7.5 mg or 15 mg - with advice to always begin with 7.5 mg once daily for a sufficient time to judge its impact on the underlying disease and the associated pain. It may be taken with or without food. A relatively new orally disintegrating tablet is available at a premium price for those unable to swallow a pill.

A new intravenous preparation for in office use or in ambulatory settings supposedly provides pain relief for 24 hours. Some recent investigations indicate relief only lasts for the first 18 hours with no better relief than placebo for the final 6 hours. Additionally some evidence indicates both Mobic and Celebrex provide less pain relief than full doses of other NSAIDS.

As with any drug, the side effect profile suggests the smallest practical dose for the shortest period of time. Important toxicity relates to the gastrointestinal system with bleeding, ulceration and perforation. Cardiovascular issues include the potential for heart attack and stroke. These issues occur in all of the NSAIDS in use today although the potential for harm might be lowest with Mobic.

Other problems include kidney injury when prostaglandins are important for maintaining renal blood flow. Especial caution is necessary in the elderly and those with dehydration from vomiting, diarrhea or inadequate fluid intake. Risks further increase with pre-existing renal or liver impairment and in those receiving ACE inhibitors or ARBs for control of blood pressure.