Propofol Side Effects

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How long does it take anesthesia to leave your body? Dr. Kaveh LIVE Side Effects 1 Views • 16 days ago

#mentalhealthmatters #surgeryrecovery #pharmacology

How long does it take to wake up after surgery? Why do some people wake up delirious?

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In this video, we discuss a critical topic: the length of time anesthesia stays in the body post-surgery. We focus on specific factors such as the type of anesthesia used, the kind of surgery performed, the pre-existing mental health state, and the history of substance use, including marijuana or cannabis.

Key anesthetics like Propofol, Fentanyl, Remifentanil, Sufentanil, Hydromorphone, and Midazolam are addressed. The decision to use and the dosage of these anesthetics hinge on individual patient requirements and the type of surgery. The dosage influences the duration these anesthetics stay in the body, how quickly they metabolize, and how long it takes for the patient to regain consciousness post-anesthesia.

The type of surgery significantly affects anesthesia duration in the body. Cardiac surgeries and neurosurgeries, for instance, necessitate higher doses of anesthesia due to their complex and lengthy nature. The larger dosage subsequently requires a longer period for the body to metabolize and redistribute the anesthesia.

Neurosurgery, in particular, merits a closer look. As these operations directly impact the brain, an organ that takes a longer time to recover due to its complexity, a higher anesthetic dosage is required. This requirement inevitably leads to a more extended wake-up period from the anesthesia. The body must redistribute and metabolize the high drug concentrations, and the brain needs to re-establish its usual functions after the invasive procedure.

The mental health state of a patient before surgery also affects anesthesia use. Patients with more anxiety or unresolved PTSD often need higher anesthesia dosages and subsequently experience a longer wake-up time. These conditions may also increase the risk of emergence delirium, a state of confusion that can occur post-anesthesia, further extending the recovery period.

Additionally, a history of substance use, particularly marijuana or cannabis, influences the dosage and metabolism of anesthesia. Frequent marijuana users may need more anesthetics due to increased tolerance, extending the time for recovery as the body works to metabolize the higher dosage.

Each patient responds to anesthesia differently, and these variables make it challenging to predict the exact recovery time post-anesthesia accurately. Providing complete and accurate medical history aids healthcare providers in administering appropriate care.

This video is a deep dive into the world of anesthesia and its journey in the body. We examine how various factors can influence its effects, its metabolization, and its significant impact on patient care and recovery. For specific advice regarding your health, consult with your healthcare professional.

This video/speech/channel DOES NOT CONSTITUTE MEDICAL ADVICE. Patients with medical concerns should contact their physician. If your concern is an emergency, immediately call 911. This information is not a recommendation for ANY THERAPY. Some substances referenced in this content may be illegal, and this content is not a recommendation for, or endorsement of, their use in any way.

What Are The Side Effects Of IV Propofol? - Pharmaceutical Insights Side Effects 0 Views • 16 days ago

What Are The Side Effects Of IV Propofol? In this informative video, we will discuss intravenous Propofol, a widely used anesthetic known for its rapid effects and short duration. Understanding the potential side effects associated with this medication is important for anyone considering its use. We will cover both common side effects, such as low blood pressure and respiratory depression, as well as more serious reactions like allergic responses and Propofol Infusion Syndrome. Additionally, we will touch on long-term effects that some patients may experience, including cognitive changes and elevated triglycerides.

Monitoring during the administration of Propofol is vital to ensure patient safety, and we will highlight the importance of close observation by healthcare professionals. It is also essential to be cautious about activities such as driving or operating heavy machinery until the medication has fully cleared from your system.

By being informed about these side effects, patients can better prepare for their medical procedures and have meaningful discussions with their healthcare providers. Join us for this important discussion and subscribe to our channel for more helpful information on medications and medical procedures.

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About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

How Anesthesia Affects Your Brain And Body Side Effects 1 Views • 16 days ago

Millions of Americans are administered anesthesia each year. Since 1846, doctors have used a variety of drugs to make patients unconscious for surgery, but even though the medications have changed, there's one thing that remains the same— it works. But how exactly?

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Following is the transcript of the video:

Narrator: When you go to sleep, if I pinched you, you'd be up. If I shook you, you'd be up, right? But under anesthesia, I'm gonna pinch you and do a full operation and you're not up. So it's really further on the spectrum of unconsciousness.

Narrator: When you wake up after being put under with general anesthesia you barely feel like any time has passed. You could have been out for an hour or a day and you wouldn't know the difference.

Fong: When you go to a natural sleep, people call your name, your alarm goes off, you wake up, right? This is not what is gonna happen during general anesthesia. You're gonna be unconscious.

Narrator: You're closer to being in a coma than being asleep.

Anesthesia was first used during surgery in 1846. The drug provided at that time was ether. Now anesthesiologists more commonly use a combination of drugs like propofol and fentanyl which interrupt neural pathways so you don't feel pain and you don't remember the surgery.

Fong: Three things that you need for general anesthesia are you need amnesia so that they don't remember, analgesia so they have pain relief and then operating conditions for the surgeon. Some surgeries you need the patient to be very relaxed so you would use a muscle relaxant. Other surgeries the patient just needs to be asleep and anesthetized but they don't need relaxation so how they do that varies upon the different medications that you're using. Some will depress excitatory neurons and some will enhance inhibitory neurons.

Narrator: Excitatory neurons, for example, get excited and send signals to other neurons to fire. Depressing them means less signals telling your brain you're in pain. Inhibitory neurons do the opposite. They make it harder for neurons to generate these electrical signals. In either case this means fewer active neurons overall which is important because when your body is being poked and prodded, neurons would typically fire to tell your brain you're in pain. If those neurons aren't firing, your brain doesn't know that your body is, well, being cut open.

Fong: Basically it interrupts the pathways and the communication between your neural networks. We're aiming for them to be not in pain by looking at their vital signs, their heart rate, their blood pressure. Then we want to make sure that they're unconscious.

Narrator: Without anesthesia, many important surgeries wouldn't be possible because they'd be way too traumatic.

Fong: Surgery didn't move forward, really, until anesthesia moved forward. You know, you watch those old movies. They give you a swig of alcohol, they put a tourniquet and they hack your leg off. People don't do well with that, right? If you had a bad heart, that would be the end of that.

Narrator: After the procedure is complete the doctors stop administering the meds and the most powerful effects of the drugs wear off but even though you're conscious again you might continue to experience some of the drugs side effects.

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Propofol Side Effects

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