Tacrolimus topical is used on the skin to treat moderate to severe atopic dermatitis in patients who have received other medicines that have not worked well.

Video Content:
0:00 Tacrolimus Ointment
0:26 How to use
0:57 Contraindications
1:42 Warnings
2:07 Side effects

Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor.

#Tacrolimus #dermatitis #medicine

@diseasesandmedicines

What is Tacrolimus? What is Tacrolimus used for?

Tacrolimus, known commercially as Prograf®, is a medication that suppresses the immune system. Its primary use is to reduce the body’s natural immune response, helping prevent or manage graft-versus-host disease (GVHD) in patients who have undergone bone marrow transplantation.

Tacrolimus is available in capsule forms of 0.5 mg, 1 mg, and 5 mg, as well as an orally-administered suspension (liquid) prepared by pharmacies. It can also be administered as a clear liquid through intravenous infusion (IV).

Potential Side Effects of Tacrolimus

Initial Side Effects:

Nausea and vomiting
Later Side Effects (occurring usually after one day of treatment):
Reduced kidney function
Diminished liver function
High blood pressure
Headaches
Increased infection risk
Abdominal pain
Insomnia
Tremors
Visual disturbances
Seizures
Low blood magnesium
Elevated blood potassium
High blood sugar levels
These are some common side effects, but others may also occur.

Specific Usage Instructions for Tacrolimus

Tacrolimus should be taken either one hour before or two hours after meals on an empty stomach. If stomach issues arise, it can be taken with food.
Consistency is key. Take it at the same time each day, maintaining a consistent relationship with meal times to ensure stable tacrolimus levels in the body.

Capsules must be swallowed whole without crushing, cutting, or chewing.
Store capsules at room temperature and shake the oral liquid well before each use. Dispose of any remaining liquid after the expiration date.
Keep out of reach of children and pets.
If a dose is missed and there's more than 4 hours until the next dose, take it immediately. If the next dose is due within 4 hours, skip the missed dose and continue as scheduled. Never double dose unless directed.
Mix liquid tacrolimus with orange or apple juice (avoid grapefruit juice) for improved taste, and consume immediately.
Re-administer the dose if vomiting occurs within 20 minutes of taking it.
Drink plenty of fluids to reduce kidney damage risk.
Avoid antacids like Tums® or Mylanta® within 2 hours of taking tacrolimus.
Regular blood tests will monitor potassium, magnesium, kidney, and liver function.
Ensure a consistent supply of the medication, contacting the pharmacy for refills when necessary.
Tacrolimus increases sun sensitivity; wear protective clothing and sunscreen, and avoid direct sun exposure and tanning bulbs.
Some medications can affect tacrolimus levels or side effects. Always inform healthcare providers about all medications being taken.
When receiving tacrolimus via IV, it will be administered over 24 hours in a hospital setting with monitoring by medical staff.
Blood levels of tacrolimus will be regularly checked. Do not take the medication on the day of a blood test until after the sample is collected. Inform your doctor or pharmacist if tacrolimus has been taken before the test.

00:00 Tacrolimus Introduction
00:22 Side Effects
01:10 Usage Instructions
02:07 Important Precautions
03:26 Blood Level Tests

#Tacrolimus #TacrolimusSideEffects #MedicinesTacrolimus #TacrolimusCream #TacrolimusMechanismOfAction #TacrolimusDosage #TacrolimusOintment #TacrolimusInjection #TacrolimusInstructions #TacrolimusIV #TacrolimusXR #UseTacrolimus #TacrolimusDose #TacrolimusUses #TacrolimusLevel #SafetyTacrolimus #TacrolimusTablet #TacrolimusEczema #TacrolimusReview #TacrolimusDosing #TacrolimusCapsule #TacrolimusReviews #TacrolimusAnalogs #TacrolimusForWhat #Prograf

This video from UC Health provides essential information about managing medications after a kidney transplant. Pharmacist Nick Parrish guides you through key details to help you understand your prescriptions.

Learn about common immunosuppressant medications like Tacrolimus (Prograf), Mycophenolate (CellCept), and Prednisone – their purpose, dosage, and how to take them correctly.

Understand potential side effects and important tips for managing your medication schedule, including blood level monitoring and food considerations.

Discover how to use a medication instruction card and pillbox to organize and remember your medications.

This video is your guide to medication management post-transplant, ensuring you stay informed and confident in your care.
Music

Tacrolimus is important drug taken by kidney transplant medication. Video is about Tacrolimus drug, its level testing, side effects, Do's and don't.

This video is about your Tacrolimus, an immunosuppression drug which is one of the transplant medications

You will take medications called immonsuppressive drugs for the rest of your life beginning immediately following your kidney transplant. Discusses the importance of planning for their cost and the side effects of the steroids and other medications you will need. Sixth in a series of 7 patient education videos for kidney recipients at the University of Michigan Transplant Center.

Modigraf/Prograf capsules and infusion contain the active ingredient tacrolimus, which is a type of medicine called an immunosuppressant. Immunosuppressants are used to dampen down the activity of cells in the immune system.

In this video, we look into what Tacrolimus is, its primary uses in the medical field, especially for organ transplants, and the potential benefits and side effects associated with this powerful immunosuppressant.







#medication #dha #fpge #mbbs #medicalstudent #moh #pharmacology #haad #pharmanotes #pharmd #autoimmunedisease #immunocompromised #treatments #therapeutics #healthcare #healthawareness #organtransplant #transplants #immunity #competitiveexams #pharmacotherapeutics #education

Before you start taking Tacrolimus, make sure to read the Patient Information Leaflet from your pharmacist. Take this medication exactly as directed by your doctor, usually every 12 hours. It can be taken with or without food, but it's important to choose one way and stick to it to ensure consistent absorption.

If you are taking the capsules, swallow them whole and do not open or crush them. If you are using the granules, be sure to follow the manufacturer's Instructions for Use and use non-plastic cups, spoons, or oral syringes. Do not sprinkle the granules on food and do not prepare the mixture ahead of time.

The dosage of Tacrolimus is based on your weight, medical condition, lab tests, and response to treatment. It's important to take this medication regularly at the same times each day to keep the amount of medicine in your body at a constant level and get the most benefit from it.

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. And if you are pregnant or may become pregnant, do not handle this medication or breathe the dust from the capsules.

Remember to consult your doctor if your condition worsens.
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Tacrolimus is an immunosuppressive medicine which has been used in kidney transplants with excellent results for a long time. It is 10 times more potent than Cyclosporin which is another similar medicine which has previously been used in difficult patients with Nephrotic syndrome both children and adults. It is used in kidney transplant,Nephrotic syndrome, SLE and other immunological diseases. My research paper, when I was a Professor at SGPGIMS, for the first time proved that this could be a new treatment for these difficult children with nephrotic syndrome. It has a response rate of 80% even n steroid resistant nephrotic syndrome. However it needs close monitoring by an experienced nephrologist.
#newtreatmentfornephroticsyndrome
#thekidneyklinic
#Taclevels

Introduction: 0: 14
Why am I taking this medication: 0: 30
How should I use this medication: 0: 50
Dosing: 2:15
What if I miss a dose: 3:40
What side effects can occur: 4:28
What to tell my HCP before taking this medication:: 5:16
Where should I store my medication: 6:15
The Renal Warrior! : 6:58

Are you dealing with nausea from Prograf or Tacrolimus? If so todays episode will be for you. I’ll give you a couple of tips that will help with the nausea associated with prograf and other immune suppressant drugs.

Transplant patient information about the medication Tacrolimus (Prograf®) presented by Chelsea Sammons, PharmD, BCPS, Clinical Pharmacy Specialist - Liver Transplantation
#pennmedicine

@americansocietyoftransplan544 with support of @Eurofins Transplant Genomics welcomes the Transplant Pharmacy Community of Practice to discuss common misconceptions regarding transplant medication side effects. If you currently take or may soon take medications such as tacrolimus, mycophenolate, or prednisone this video will guide you through expectations and communication tips to share with your transplant physician.

Tacrolimus is a medication that belongs to a class of drugs known as calcineurin inhibitors. It is primarily used as an immunosuppressive agent, which means it is used to suppress the immune system's response. This property makes tacrolimus particularly useful in various medical situations, most notably in organ transplantation and the treatment of certain autoimmune conditions.

Here are some key points about tacrolimus:

1. Immunosuppression: Tacrolimus works by inhibiting the activity of calcineurin, an enzyme crucial for the activation of T-lymphocytes (T cells), which are a type of white blood cell involved in immune responses. By inhibiting T-cell activation, tacrolimus helps to reduce the immune system's activity. This is especially important in organ transplantation, where the immune system might recognize the transplanted organ as foreign and attack it.

2. Organ Transplantation: Tacrolimus is commonly used to prevent organ rejection in patients who have received an organ transplant, such as a kidney, liver, heart, or lung transplant. After transplantation, the body's immune system can identify the transplanted organ as foreign tissue and try to attack and destroy it. Tacrolimus helps prevent this rejection and allows the recipient's body to accept the new organ.

3. Autoimmune Disorders: Tacrolimus can also be used to treat certain autoimmune disorders, where the immune system mistakenly attacks the body's own tissues. Conditions like rheumatoid arthritis, psoriasis, atopic dermatitis, and certain forms of inflammatory bowel disease may be managed with tacrolimus to suppress the abnormal immune response and alleviate symptoms.

4. Topical Formulation: In addition to its systemic use (oral or intravenous administration), tacrolimus is available in a topical form (ointment or cream). Topical tacrolimus is often prescribed to treat conditions like eczema (atopic dermatitis). It helps to reduce inflammation, itching, and redness associated with these skin conditions by targeting the immune response directly at the site of application.

5. Side Effects: Like most medications, tacrolimus can have side effects. These can include issues like increased susceptibility to infections due to the suppressed immune response, high blood pressure, kidney problems, and an increased risk of certain cancers. Close monitoring by a healthcare professional is necessary to manage these risks and adjust the dosage as needed.

6. Dosage and Administration: The dosage of tacrolimus can vary depending on factors such as the patient's age, the specific medical condition being treated, and how the drug is being administered (oral, intravenous, or topical). Regular blood tests are often required to monitor the drug's levels in the body and its effect on the immune system.

7. Drug Interactions: Tacrolimus can interact with other medications, so it's important for healthcare providers to be aware of all the medications a patient is taking to avoid potential interactions that could affect the drug's effectiveness or increase the risk of side effects.

It's important to note that tacrolimus is a potent medication that requires careful monitoring and management by healthcare professionals. This overview provides general information, but if you have specific questions about tacrolimus or its use in a particular medical context, it's recommended to consult a qualified healthcare provider.