A little more than one month ago I began taking Rinvoq for my ankylosing spondylitis. The effectiveness of my second biologic has shown signs of being ineffective; my chronic pain had become worse and my movements had become more limited. My doctor recommended that I consider Rinvoq, a medication that is still not approved for use here in British Columbia. This video summarizes my findings.

Please note that in spite of the years with ankylosing spondylitis, I had maintained a very healthy lifestyle: a diet that was primarily plant-based, stress reduction techniques, good sleep, and a disciplined regimen of exercise. I believe that my healthy lifestyle was the primary reason that I have had such immediate effects with this new medication.

This is my latest update after a little over 2 month on Rinvoq.

Nina Torres' battle against RA #HighRiskCovid19

Let's delve into the realm of eczema treatment with dermatologist, Dr Angeline Yong as she talks about the development of JAK Inhibitors for Atopic Dermatitis. In this video, Dr Yong sheds light on its complexities and the potential of JAK Inhibitors, the treatment that is changing the landscape of eczema treatment.

Whether you're seeking insights as a patient, healthcare professional, or someone interested in medical advancements, this video provides a comprehensive overview of the eczema treatment. Join us in unraveling the potential of JAK Inhibitors for Atopic Dermatitis. Remember to like, share, and subscribe to stay informed about skin health and innovation.

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After my second biologic showed signs of being less effective, I began treatment with Rinvoq, a relatively new medication, a daily pill rather than a weekly injection. Before starting, I searched on the Internet for reviews from people with ankylosing spondylitis regarding its effectiveness. Sadly, I found nothing. For this reason, I have decided to begin to submit my feelings about using Rinvoq to help others who might be considering the use of this medication.

Discover the reasons behind my decision to discontinue Rinvoq and revert to Cellcept for managing my autoimmune condition. In this video, I share my personal experience, insights, and the factors that led me to switch treatments. Join me as I navigate the ups and downs of finding the right medication for my health journey. If you're considering treatment options, this honest account might offer valuable perspective. #Autoimmune #Rinvoq #Cellcept"

Welcome to a comprehensive exploration of Rinvoq, a notable medication with a multifaceted mechanism of action and significant implications in the treatment of ulcerative colitis. This guide aims to provide an in-depth understanding of Rinvoq, its mechanism, potential side effects, and how it contributes to managing ulcerative colitis effectively.

Rinvoq: A Mechanistic Breakdown

Rinvoq is a medication classified as a Janus kinase (JAK) inhibitor. Janus kinases are enzymes that play a pivotal role in the signaling pathways associated with inflammatory responses. Rinvoq inhibits specific Janus kinases, particularly JAK1, JAK2, and to a lesser extent, JAK3. By doing so, it modulates the signaling of multiple pro-inflammatory cytokines involved in the pathogenesis of various inflammatory diseases, including ulcerative colitis.

Understanding Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by inflammation and ulcers in the mucosal lining of the colon and rectum. The inflammation typically starts in the rectum and can extend continuously into the colon. Common symptoms include abdominal pain, diarrhea, rectal bleeding, and an urgent need to move the bowels.

Rinvoq's Role in Ulcerative Colitis Management

Given its mechanism of action as a JAK inhibitor, Rinvoq has shown promise in managing the symptoms and inflammation associated with ulcerative colitis. By inhibiting specific signaling pathways, Rinvoq helps to regulate the immune response and reduce inflammation in the colon, ultimately providing relief to individuals affected by this chronic condition.

Potential Side Effects of Rinvoq

Infections:
One of the potential side effects of Rinvoq is an increased susceptibility to infections. Since Rinvoq affects the immune system, it may reduce the body's ability to fight off infections effectively. Common infections may include upper respiratory tract infections and urinary tract infections.

Gastrointestinal Issues:
Rinvoq use may be associated with gastrointestinal issues such as nausea, diarrhea, and abdominal pain. These symptoms may vary in severity, and it's essential to communicate any discomfort to your healthcare provider.

Changes in Blood Test Results:
Rinvoq can cause alterations in certain blood test results, including changes in liver function tests, cholesterol levels, and blood counts. Regular monitoring is crucial to track these changes and ensure the medication's safety and efficacy.

Allergic Reactions:
Although rare, Rinvoq may trigger allergic reactions in some individuals. Signs of an allergic reaction may include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. Immediate medical attention is required if such symptoms occur.

Elevated Blood Pressure:
Rinvoq use may lead to increased blood pressure in some individuals. Monitoring blood pressure regularly and informing the healthcare provider of any significant changes is vital.

Balancing Benefits and Risks in Ulcerative Colitis Treatment

The decision to use Rinvoq in the management of ulcerative colitis involves a careful consideration of its benefits in reducing inflammation and symptoms against potential side effects. Healthcare professionals weigh these aspects to tailor the treatment plan to each individual, striving for the most effective and well-tolerated therapy.

In conclusion, Rinvoq presents a promising avenue in the management of ulcerative colitis, offering a targeted approach to address inflammation and its associated symptoms. Understanding its mechanism of action and potential side effects equips both healthcare providers and patients with the knowledge needed to navigate this treatment option effectively.

Thank you.
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"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.



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Rinvoq represents the third janus kinase inhibitor marketed in the United States. Xeljanz and Olumiant preceded Rinvoq. All are indicated for treatment of moderate to severe rheumatoid arthritis. Humira will lose patent protection in America in 2023 and face stiff competition from biosimilars. Rinvoq will be heavily advertised by AbbVie since it faces severe deterioration in its $20 billion a year golden goose - Humira - the most revenue derived from any single drug.

While the company quotes the annual price for Rinvoq at about $59,000, an individual paying cash for Rinvoq at the pharmacy can expect the cost to approximate $90,000. Through a sleight of hand the company offers Rinvoq copay assistance to limit the out of pocket burden, shield the consumer from sticker shock and pass the financial liability to the insurance company. Of course this results in an ever increasing spiral of premiums for everyone.

Unquestionably Rinvoq provides significant improvement for many with rheumatoid arthritis. But unfortunately its relative place among the various options lacks study. Other therapies include methotrexate, hydroxychoroquine, sulfasalazine, Simponi, Enbrel, Remicade, Humira, Actemra and the other janus kinase or JAK inhibitors. Of course many individuals with mild rheumatoid arthritis do well with aspirin, ibuprofen or naproxen.

With the billions of dollars these drugs transfer to the pharmaceutical industry, a study comparing the various options would be greatly welcome. Too often advertising drives prescriptions. And it can be expected that some individuals with mild disease will receive Rinvoq when it is not indicated. By the way, methotrexate costs as little as $20 a month without any insurance or other gimmicks.

This is a video about Understanding Rinvoq for Autoimmune Conditions

00:00 Understanding Rinvoq for Autoimmune Conditions

Rinvoq Side Effects
**Common Side Effects (≥5%):**

* Nasopharyngitis (common cold)
* Nausea
* Diarrhea
* Headache
* Fatigue
* Dizziness
* Upper respiratory tract infection
* Increased white blood cell count (leukocytosis)
* Abdominal pain
* Rash
* Dyspepsia
* Dry mouth
* Vomiting
* Pruritus (itching)
* Back pain
* Muscular pain
* Urinary tract infection

**Less Common Side Effects (1-5%):**

* Infusion-related reactions (e.g., anaphylaxis, allergic reactions)
* Hypersensitivity
* Injection site reactions (e.g., erythema)
* Lymphadenopathy
* Peripheral edema
* Tachycardia
* Hypertension
* Dyspnea
* Throat irritation
* Rhinitis (runny nose)
* Sinusitis
* Conjunctivitis
* Stomatitis (mouth sores)
* Toothache
* Muscle spasms
* Vertigo
* Tinnitus
* Insomnia
* Abnormal liver function tests
* Increased creatine phosphokinase
* Increased glucose level
* Decreased appetite
* Weight loss
* Anxiety
* Depression
* Vision changes
* Blurred vision
* Cataracts
* Retinal vein occlusion
* Chorioretinitis (inflammation of the middle layer of the eye)
* Macular edema
* Acne
* Psoriasis
* Herpes simplex
* Shingles
* Fungal infections
* Bacterial infections
* Mycobacterium tuberculosis infection
* Cytomegalovirus infection
* Pneumocystis jirovecii pneumonia
* Aspergillosis
* Candidiasis
* Latent tuberculosis infection
* Histoplasmosis
* Cryptococcosis
* Blastomycosis

**Rare Side Effects (1%):**

* Serious infections (e.g., bacterial, viral, fungal, parasitical)
* Sepsis
* Death
* Malignancy (e.g., lymphoma, nonmelanoma skin cancer, colorectal cancer, breast cancer)
* Optic neuritis
* Vasculitis
* Lupus
* Thromboembolism (e.g., deep vein thrombosis, pulmonary embolism)
* Stroke
* Heart attack
* Guillain-Barré syndrome
* Transverse myelitis
* Drug reaction with eosinophilia and systemic symptoms (DRESS)
* Stevens-Johnson syndrome
* Toxic epidermal necrolysis
* Acute pancreatitis
* Pancreatitis
* Cholangitis
* Hepatic failure
* Kidney failure

**Note:** This is not an exhaustive list. It is important to discuss potential side effects with your healthcare provider before starting treatment with Rinvoq.

Rinvoq review of my first 2 weeks including any rinvoq side effects I experienced. I took Rinvoq to treat my Ulcerative Colitis which is a form of IBD like Chron's Disease. I hope my experiences will be of some use to other patients and prospective patients. I tried to review rinvoq and my experiences so far. I think Rinvoq is helping my Ulcerative Colitis.

I am not a doctor this is not medical advice of any kind. Your body and experiences will differ from mine.

#rinvoqreview #ulcerativecolitis #ibd

Late is better than never. Here is my final review of Rinvoq. There are tears at the end, but they are just frustrated tears, not sad tears, not giving up tears. I am slowly learning to edit on iMovie and was able to add a blooper at the end. Hope this helps!

The itching and infections caused by eczema can be disabling. But a new study found a drug prescribed for arthritis may be the best treatment yet for eczema patients. CBS2's Dr. Max Gomez reports.

GutTalk TV by Dr Yoon An and Dr Jakob Begun (IBD specialists from Australia). They go through the "ins and outs" of IBD advanced therapy in attempt to answer all your questions.
- Why am I being treated with this medicine?
- How does it work?
- How long will it take to work?
- How do I take upadacitinib?
- What are the possible side effects of upadacitinib?
- How will I be monitored on this medication?
- Can the medication be used in pregnancy? What about breastfeeding?

In today’s Health Alert, a new drug has been approved by the FDA to treat moderate-to-severe Crohn's Disease. It’s called Rinvoq - it’s a pill that adults can take daily.

Rinvoq is a Janus kinase (JAK) inhibitor. It works inside your cells to block certain signals that are thought to cause inflammation.

Video Content:
0:00 Rinvoq tablets
0:15 Indications
0:54 How to use
2:10 Contraindications
2:45 Warnings
3:30 Rinvoq side effects

Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor.

#Rinvoq #antiinflammation #medicine