General information regarding Ceftriaxone (Rocephin). Content created leveraging AI with the goal of bridging access across communities. Please flag any suggestions or errors in the comment section. Thank you!

Are augmentin and rocephin in the same family?.
No, Augmentin and Rocephin do not belong to the same family of antibiotics. Augmentin is a combination of amoxicillin and clavulanate potassium, while Rocephin is the brand name for ceftriaxone.
Augmentin is a penicillin-type antibiotic that is effective against a wide range of bacteria. It works by inhibiting the growth of bacteria cell walls, ultimately killing them. This medication is commonly prescribed to treat various infections, such as respiratory tract infections, ear infections, and urinary tract infections.
On the other hand, Rocephin belongs to the cephalosporin class of antibiotics. It works by disrupting the bacterial cell wall and inhibiting bacterial growth. Rocephin is often used to treat more severe infections, including meningitis, pneumonia, and gonorrhea.
Although both Augmentin and Rocephin are antibiotics, they have different chemical structures and mechanisms of action. Therefore, they are not considered to be in the same family of antibiotics.


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General information regarding Rocephin (Ceftriaxone). Content created leveraging AI with the goal of bridging access across communities. Please flag any suggestions or errors in the comment section. Thank you!

👉💯 En este video te vamos a mostrar que es ROCEPHIN, para que sirve, como tomarlo y cual es la dosis recomendada. Tambien los efectos secundarios de este antibiotico.

Ceftriaxone ပိုးသတ်ဆေးအကြောင်း အစအဆုံး
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Tips to guide students and nurses on how to program an IV pump to give the entire dose of IV antibiotics (a skill which 95 percent of RNs fail).

Key: Program the IV pump with sufficient "volume to be infused" to empty ALL of the antibiotic out of the IV tubing. Use Holt's IV Rule Number 2.

Adapted from "25 to 50 percent of IV Antibiotics do not reach the patient," by David Holt, RN.
RN-IVPB.com

If only the Nursing instructors and textbooks would guide students or nurses on how to program an IV pump to give the entire dose of IV antibiotics.

Use Holt's 30 CC rule to calculate and program the right VTBI to give the entire dose of IV antibiotic.

Adapted from "25 to 50 percent of IV antibiotics do not reach the patient," by David Holt.

RN-IVPB.com

This video was made by Dinh An Ho , 2023 Pharmacist Candidate. He will review: Patient consultation points, indications, dosing and adjustments, mechanism of action, side effects, and monitoring parameters

Naplex Review
Antibiotic Review: Ceftriaxone (Rocephin)
Characteristics: 3rd Generation Cephalosporin
Long half-life (8hrs) allowing for daily dosing
Resistance to beta-lactamases
Can cross into CNS
Uses: Respiratory tract infections
UTI’s
SSTI/Bone and Joint
Gonorrhea
Sepsis
Intra-abdominal
CNS-Meningitis
Surgical prophylaxis
Microbiology:Gram negative organisms:
Including: E coli., H flu, Klebsiella, Neisseria gonorrhoeae and meningitidis, P mirabilis, Serratia
Doesn’t cover: Pseudomonas
Gram positive: Usually not used, but may have coverage
Anaerobes: C. diff is resistant
Administration: IM or IV
IM administration: Dilute according to package insert to obtain either a 250ml or 350ml concentrations (can be diluted with sterile water, NS, D5W, or Lidocaine 1%)
IV administration: can be given as IV piggyback in 50mls/100mls over 30 minutes or given a an IV push in 10mls over 3 to 5 minutes
Pregnancy category B
Small amounts of Rocephin can be found in milk, use caution
Adverse Reactions: Generally well tolerated

The Alabama Department of Public Health (ADPH) is investigating reports of adverse reactions to injections of the antibiotic ceftriaxone, also known as Rocephin.

Ceftriaxone Antibiotics

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CEFTRIAXONE

Class: Third-generation cephalosporin antibiotic

Spectrum: Broad-spectrum; effective against Gram-positive and Gram-negative bacteria

Indications:
- Severe infections (sepsis, meningitis)
- Community-acquired pneumonia
- Gonorrhea (including penicillin-resistant strains)
- Lyme disease (alternative)
- Intra-abdominal infections (with metronidazole)
- Surgical prophylaxis (selected cases)

Dosing:
- Adults: 1–2 g IV/IM once daily (up to 4 g/day in severe infections)
- Pediatrics: 50–100 mg/kg/day (max 4 g/day)
- Meningitis: 100 mg/kg/day (max 4 g/day)

Administration:
- IV (over 30 mins) or IM (with lidocaine for pain)
- NOT for intraventricular or intrathecal use

Side Effects:
- Diarrhea, nausea, rash
- Transient LFT abnormalities
- Biliary sludge/"pseudolithiasis" (with prolonged use)
- Hematologic (eosinophilia, thrombocytosis, rarely neutropenia)

Contraindications:
- Hypersensitivity to cephalosporins
- Severe penicillin allergy (cross-reactivity risk)
- Neonates (if calcium-containing solutions due to precipitation risk)

Drug Interactions:
- Calcium-containing solutions: Risk of precipitation (avoid concurrent IV use in neonates)
- Warfarin: Increased INR (monitor coagulation)
- Probenecid: Delays renal excretion
- Pregnancy/Lactation: Category B; excreted in breast milk (use with caution)


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