Olanzapine Side Effects
Olanzapine Full Review | Side Effects | Dosage | Dr Aneel Shafi
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Mel talks about a recent study discussing intramuscular droperidol or olanzapine for acute agitation.
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What are the uses of Olanzapine? #TrustTheExperts
Olanzapine is a psychiatric medication used to treat the symptoms of schizophrenia.
Schizophrenia is a mental disorder that causes hallucinations, distorted thinking, loss of interest in life, and intense or inappropriate emotions.
Olanzapine is also used to treat bipolar disorder, a psychiatric disorder characterized by prolonged periods of alternating mania and depression.
The medication is usually prescribed to people who are 13 years and older. The drug is effective by bringing about changes in brain activity.
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This is a clip from our Livestream on February 24th, 2024. Full video here: https://www.youtube.com/live/4....FyxbMYPh9w?si=_NvOvw
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📚 Useful Resources:
Stahl's Prescribing Guide: https://amzn.to/4bjHlHe
Deprescribing Guide: https://amzn.to/3XBkIuA
Drug Interaction Checker-https://www.drugs.com/drug_interactions.html
Brain Food Report- https://www.levelheadedmind.com/brainfoodreport
Neurotransmitter Questionnaire- https://www.levelheadedmind.co....m/neurotransmitter-a
Recommended Reading: https://www.levelheadedmind.com/books
🎥 This video was edited by:
Rahul Kanchi https://www.linkedin.com/in/rahul-kanchi/
🚑 If you are in a mental health crisis, please dial 9-8-8 from the U.S. Or text HOME to 741741 and connect to a crisis counselor.
You can find a list of international crisis lines here: https://blog.opencounseling.com/suicide-hotlines/
Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own healthcare provider for proper diagnosis and treatment.
Note: This video is not sponsored. Some of the links provided are affiliate links, meaning I may earn a small commission from purchases made through those links.
In today's video, we're diving deep into the world of Zyprexa, a widely prescribed atypical antipsychotic. With millions relying on this medication to combat severe psychosis, it's crucial to understand both its potential benefits and the risks involved. 😮
We'll dissect the manufacturer's clever use of the word "safety" and reveal what they're NOT telling you about the drug's true nature. As a powerful antipsychotic, Zyprexa can induce sleep and calm acute episodes of psychosis and mania, but it's not without its dangers. ⚠️
Get the lowdown on Zyprexa's side effects, why it's only approved for those 13 years and older, and the available forms of administration (oral tablets and injections). 💉
Plus, don't miss some eye-opening facts and anecdotes about this controversial drug. You don't want to miss this critical and informative discussion! 👁️
Join us now and be part of an essential conversation. Like, comment, and share to spread awareness! 🔥🎥 #Zyprexa #Antipsychotic #MentalHealth
References:
https://pubmed.ncbi.nlm.nih.gov/9285972/
https://pi.lilly.com/us/zyprexa-pi.pdf
https://pubmed.ncbi.nlm.nih.gov/24551889/
https://pi.lilly.com/ca/zyprexa-ca-pm.pdf
Youtube video about woman talking about her Zyprexa withdrawals/sleep disturbances: https://www.youtube.com/watch?v=j6fCpkPDDSM&t=151s&ab_channel=Davison%28DavisonVideo%29
In this episode, I discuss a medication known as olanzapine (Zyprexa) and go over three things that you should know while using it:
1. Weight Gain
2. Orthostatic Hypotension
3. Black Box Warning
My book is now available! It discusses my experience with Bipolar Disorder.
The Fifth Episode - Inside The Manic Mind.
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For information purposes only!
Sometimes psychiatric drug design feels like a recycling bin filled with old ideas. Today is an opportunity for us to expose some of the flaws in one of the latest recycled ideas in psychopharmacology using samidorphan an opioid receptor blocker to alleviate the metabolic side effects of olanzapine.
Time Stamps
Introduction: 00:00 to 01:05
Why Olanzapine without weight gain is important: 01:06 to 02:54
Results Weight gain and Lipids ENLIGHTEN-Early Study: 02:55 to 04:22
Conclusion: 04:23 to 05:05
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Disclaimer: This is not medical advice, and the information is provided for educational purposes only. Please consult your doctor for any specific medical questions. All content is created for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider. If you think you have a medical emergency, call your doctor, go to the emergency department, or call 911. We do not endorse any specific treatment, tests, or procedures. Reliance on this information is solely at your own risk.
I was on Zyprexa from December of 2018 to July of 2021 took a break, then restarted and I've been on it ever since. This is my experience on this powerful and effective drug!
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Easy Links to Learn More:
Drugs.com - https://www.drugs.com/monograph/olanzapine.html
Medline Plus - https://medlineplus.gov/druginfo/meds/a601213.html
Healthline - https://www.healthline.com/hea....lth/olanzapine-oral-
MedicineNet - https://www.medicinenet.com/ol....anzapine/article.htm
Papers about atypical antipsychotics causing OCD or making obsessive compulsive symptoms worse:
"Olanzapine and obsessive-compulsive symptoms" - https://pubmed.ncbi.nlm.nih.gov/10974610/
"Obsessive–compulsive symptoms with olanzapine" - https://pubmed.ncbi.nlm.nih.gov/15231024/
"Clozapine-Induced Obsessive-Compulsive Symptoms in Schizophrenia: A Critical Review" - https://pubmed.ncbi.nlm.nih.gov/22942882/
Paper mentioned about Seroquel helping OCD symptoms:
"Is quetiapine effective for obsessive and compulsive symptoms in patients with bipolar disorder? A randomized, double-blind, placebo-controlled clinical trial" - https://pubmed.ncbi.nlm.nih.gov/34027853/
Other papers/sources:
"FDA Approves Symbyax(R) as First Medication for Treatment-Resistant Depression" - https://investor.lilly.com/new....s-releases/news-rele
"The Maudsley Prescribing Guidelines in Psychiatry" (See page 16!) - https://books.google.com/books?id=XvOyBwAAQBAJ&pg=PA16#v=onepage&q&f=false
Yes, I am aware of the weird blinds effect that happens in the latter part of this video.
Disclaimer: I am not a qualified mental health professional. This channel exists for educational purposes, and I do my best to provide accurate and up-to-date information. In order to create content, I combine scientific resources (peer reviewed studies and easy-to-understand articles) and my own personal experiences/advice. I seek to make complicated topics easy to understand, but I am no substitute for a doctor, therapist, or other qualified mental health professional.
While Olanzapine is an effective medication, it’s side effect profile can be nasty. Things like weight gain, changes in blood lipids, and changes in blood glucose are common. ALKS 3831 attempts to fix this problem by adding Samidorphan to olanzapine to reduce weight gain.
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Disclaimer: This is not medical advice, and the information is provided for educational purposes only. Please consult your doctor for any specific medical questions.
All content is created for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider. If you think you have a medical emergency, call your doctor, go to the emergency department, or call 911. We do not endorse any specific treatment, tests, or procedures. Reliance on this information is solely at your own risk.
In this video we will cover everything you need to know about Olanzapine, also known as Zyprexa. This video is part of a video series on mental health problems. So for more mental health related videos check out this playlist:
https://www.youtube.com/playli....st?list=PLaG3Bo3L0gX
Generic name: Olanzapine.
Brand names: Zyprexa, zydis and zypadhera.
Available as a tablet and injection.
How to use it?
Swallow the tablet completely with half a glass of water. Do not break them and don’t chew on them.
When using injections: These will be administered by your doctor or nurse into your buttock muscle.
Duration of treatment:
The duration of treatment depends on the indication of use and the severity of your symptoms. If your symptoms improve with the use of Olanzapine you usually have to keep using it for 12-24 more months. And sometimes multiple years.
When to use it?
Olanzapine is part of a group of drugs called antipsychotics. It can be used to treat several mental health conditions:
- Schizophrenia.
- Manic episodes in bipolar disorder.
What is the correct dosage?
Unfortunately I can’t provide you with guidelines for the correct dosages, as these differ a lot depending on the specific indication, the side effects you experience and the severity of your complaints.
Usually your doctor starts with a low dose and quickly builds it up over a few days. Afterwards your maintenance dose will be adapted throughout your treatment based on the blood levels of Olanzapine you will be having.
Therefore always use the prescribed dose and frequency your doctor gave you.
What are the side-effects?
Very common (10+%): sleepiness, low blood pressure, weight gain and sexual dysfunction (erectile dysfunction, decreased libido).
Common (1-10%): increased appetite, changes in your blood values, constipation, dry mouth, dizziness, tiredness, fever, joint pain, rash and visual hallucinations.
Uncommon (0.1-1%): allergic reaction, stuttering and thrombosis.
Safety:
- You should be careful to combine Olanzapine with alcohol. As this might increase the dazing effect of Olanzapine.
- In addition it is usually safe to drive while using this drug, however it can cause you to become drowsy, sleepy and/or dizzy. If you experiencing any of these side effects then please do not drive.
- Lastly, Olanzapine can have interactions with several drugs. Therefore always discuss this with your treating physician.
Pregnancy and Lactation:
Olanzapine can often be used safely in both cases, however always discuss this with your doctor, as there are some exceptions.
- Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. -
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Literature:
1: Farmacotherapeutisch Kompas. (2020). Olanzapine
2: Apotheek.nl (2020). Olanzapine.
* The images in this video are used for educational purposes only. Most of the images and video material in this video come from https://www.canva.com/.
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Dr. Aly (psychiatrist) discusses the common medication Zyprexa (Olanzapine) so you can be better informed when deciding whether or not to try this medication. ***Link to Dr. Aly's FREE "Antidepressants: A Beginner's Guide" ➡️ https://free.dralywood.com/antidepressants
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⏰ TIMESTAMP ⏰
0:00 Intro
0:15 Zyprexa Vs Olanzapine
0:27 Fact #1: How Zyprexa Works
0:50 Fact #2: What Zyprexa Treats
1:38 Fact #3: Zyprexa Dosing
3:01 Fact #4: Side Effects Of Zyprexa
5:25 Fact #5: How To Discontinue Zyprexa
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This information is for educational and informational purposes only and solely as a self-help tool for your own use. I am not providing medical, psychological, or nutrition therapy advice. Watching the videos or getting answers to comments/questions does not establish a doctor-patient relationship. You should not use this information to diagnose or treat any health problems or illnesses without consulting your own medical practitioner. Always seek the advice of your own medical practitioner and/or mental health provider about your specific health situation. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately.
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In today's video, we are comparing 2 older second-generation antipsychotics, olanzapine, and risperidone. Time stamps of each topic covered are listed below:
Intro 00:00
How do olanzapine and risperidone work? 00:23
What are olanzapine and risperidone used for? 03:27
Side effects of olanzapine and risperidone 04:53
Considerations of taking olanzapine and risperidone 07:36
- Black box warning 07:50
- Monitor Labs 08:25
- Neuroleptic Malignant Syndrome 10:31
- Extra Pyramidal Symptoms 11:03
- Orthostatic Hypotension 12:39
- Seizures 13:20
Final thoughts 14:02
🙋🏽♀️ Join this channel to access exclusive LIVES, priority comments/questions answered, and more!:
https://www.youtube.com/channe....l/UCMzNgkZdW1dON-ZNe
📚 Useful Resources:
Deprescribing Guide: : https://amzn.to/4dZEUMk
Drug Interaction Checker-https://www.drugs.com/drug_interactions.html
Brain Food Report- https://www.levelheadedmind.com/brainfoodreport
Neurotransmitter Questionnaire- https://www.levelheadedmind.co....m/neurotransmitter-a
🎥 This video was edited by:
Rahul Kanchi https://www.linkedin.com/in/rahulkanchi24/
🚑 If you are in a mental health crisis, please dial 9-8-8 from the U.S. Or text HOME to 741741 and connect to a crisis counselor.
You can find a list of international crisis lines here: https://blog.opencounseling.com/suicide-hotlines/
References:
Alsherbiny MA, Li CG. Medicinal Cannabis-Potential Drug Interactions. Medicines (Basel). 2018 Dec 23;6(1):3. doi: 10.3390/medicines6010003. PMID: 30583596; PMCID: PMC6473892.
He, S., Yu, W. J., Wang, X., Zhang, L., Zhao, N., Li, G., Shen, Y. F., & Li, H. (2020). Risk factors of hyperprolactinemia induced by risperidone and olanzapine and their correlations with plasma glucose and lipids. General psychiatry, 33(4), e100206. https://doi.org/10.1136/gpsych-2020-100206
Olanzapine FDA Label (2009). Retrieved from https://www.accessdata.fda.gov..../drugsatfda_docs/lab
Risperdal FDA Label (2009). Retrieved from https://www.accessdata.fda.gov..../drugsatfda_docs/lab
Shoja Shafti, S., & Gilanipoor, M. (2014). A Comparative Study between Olanzapine and Risperidone in the Management of Schizophrenia. Schizophrenia research and treatment, 2014, 307202. https://doi.org/10.1155/2014/307202
Stahl, S. M., Grady, M. M., & Muntner, N. (2021). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications. Cambridge University Press.
Stahl, S. (2017). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 6th Ed. Cambridge University Press.
Uptodate (2022). Olanzapine: Drug Information. Retrieved from https://www-uptodate-com.libproxy.eku.edu/contents/olanzapine-drug-information?source=auto_suggest&selectedTitle=1~3---1~3---Olanzapine&search=olanzapine#F203123
UptoDate (2022). Risperidone: Drug information. Retrieved from https://www-uptodate-com.libproxy.eku.edu/contents/risperidone-drug-information?source=auto_suggest&selectedTitle=1~1---1~4---Risperdal&search=risperdal#F218620
Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own healthcare provider for proper diagnosis and treatment.
In this Q&A session with the Founder of Alternative to Meds Center, Lyle Murphy, find answers to the top questions about Zyprexa Withdrawal and Olanzapine Withdrawal.
Please Like, Share, And Subscribe.
-----------------------QUESTIONS-----------------------
00:00 - Intro
00:16 - What is Zyprexa?
00:25 - What is Zyprexa (Olanzapine) used for?
01:20 - What does Zyprexa Withdrawal look like?
06:46 - Am I schizophrenic if I take Zyprexa?
09:08 - What are Zyprexa Alternatives?
11:17 - Can Zyprexa cause tardive dyskinesia?
14:08 - Outro
1. What is Zyprexa? Zyprexa is an atypical antipsychotic
2. What is Zyprexa (Olanzapine) used for? Zyprexa is used in the treatment of schizophrenia and sometimes for the stabilization of bipolar. These diagnoses are sometimes however confused with hypoglycemia, drug use, and spiritual crisis.
3. What does Zyprexa Withdrawal look like? Since there is a dopamine surge coming off of Zyprexa, the withdrawal generally looks like a return of the original symptoms. Typical signs are mania, psychosis, inability to sleep, lack of desire to eat. This can be lessened by doing a very slow withdrawal and avoiding stimulants like caffeine.
To read more about Zyprexa Withdrawal and Olanzapine visit:
https://www.alternativetomeds.....com/antipsychotics/z
4. Am I schizophrenic if I take Zyprexa? No, but sometimes the drug itself can create symptoms that look like schizophrenia. There is a difference between schizoaffective and schizophrenic, which the later tends to have a more constant presentation of symptoms.
5. What are Zyprexa Alternatives? Vitamin C, Niacin, Lithium Orotate, restricting drug use, avoiding stimulants.
To read more about Zyprexa Alternatives and Olanzapine alternatives visit:
https://www.alternativetomeds.....com/blog/zyprexa-alt
6. Can Zyprexa cause tardive dyskinesia? Any antipsychotic can cause tardive dyskinesia or akathisia. Atypicals are less likely than typical antipsychotics. Certain genetic factors like the CYP2D6 or CYP3A4 polymorphisms are suspected.
Thank you for watching this video about Zyprexa.
Please like and subscribe to our page.
To learn more about Zyprexa Tapering and Olanzapine Tapering visit:
https://www.alternativetomeds.....com/blog/zyprexa-tap
To learn more about the Alternative to Meds Center, located in Sedona, AZ, please visit:
https://www.alternativetomeds.com/about/
Nothing in this video or on this description should be taken as medical advice. Please consult your doctor or consider admission to the Alternative to Meds Center where you will be under the care of a doctor during your process.
To speak with an admissions counselor call 1-800-301-3753
In this video, we discuss the top 7 things you need to know about olanzapine or Zyprexa. We discuss what olanzapine is, what it is used for, how long it takes to work, whether olanzapine is addicting, the side effects, drug interactions, and my final thoughts.
Intro 00:00
What is olanzapine (Zyprexa)- Mechanism of Action 01:00
What is olanzapinem (Zyprexa) used for? 02:09
How long does olanzapine take to work? 04:19
Is olanzapine addicting? 05:37
Side effects of olanzapine 06:31
Drug interactions related to olanzapine 11:47
My final thoughts and considerations of olanzapine 14:32
Resources:
Deprescribing Guide: https://amzn.to/4dZEUMk
Stahl's Prescribing Guide: https://amzn.to/3UXj8QL
🎥 This video was edited by:
Rahul Kanchi https://www.linkedin.com/in/rahulkanchi24/
🚑 If you are in a mental health crisis, please dial 9-8-8 from the U.S. Or text HOME to 741741 and connect to a crisis counselor.
You can find a list of international crisis lines here: https://blog.opencounseling.com/suicide-hotlines/
References:
Alsherbiny MA, Li CG. Medicinal Cannabis-Potential Drug Interactions. Medicines (Basel). 2018 Dec 23;6(1):3. doi: 10.3390/medicines6010003. PMID: 30583596; PMCID: PMC6473892.
FDA Label (2020). Retrieved from https://www-accessdata-fda-gov.....libproxy.eku.edu/dr
Uptodate (2022). Olanzapine: Drug Information. Retrieved from https://www-uptodate-com.libproxy.eku.edu/contents/olanzapine-drug-information?source=auto_suggest&selectedTitle=1~3---1~3---Olanzapine&search=olanzapine#F203123
Stahl, S. M., Grady, M. M., & Muntner, N. (2021). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications. Cambridge University Press.
Stahl,S. (2017). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 6th Ed. Cambridge University Press.
Patient Resource
https://medlineplus.gov/druginfo/meds/a601213.html
Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own health care provider for proper diagnosis and treatment.
Dr. Pagnani of Rittenhouse Psychiatric Associates discusses Zyprexa (olanzapine) which is a second generation neuroleptic or antipsychotic (SGA). Although it is referred to as an antipsychotic, this medication can be utilized in the treatment of mania (in bipolar disorder) and also can be used to treat depression (for example, augmenting an SSRI or SNRI). It has the potential for many side effects, and some of them are discussed in this video.
Dr. Pagnani is the founder and medical director of Rittenhouse Psychiatric Associates, an Instructor at The Johns Hopkins Hospital for the Department of Psychiatry, he supervises psychiatric residents at Jefferson Hospital, he serves on the Young Professional Board of Uplift, the Center for Grieving Children and he maintains a private practice of Psychiatry in Philadelphia where he sees patients for one-time psychiatric evaluations and second opinions. He is a licensed physician and surgeon in NJ, PA, NY, MD, DE, FL and CA and can provide consultations to individuals via HIPAA compliant Telehealth visits living in these locations.
Rittenhouse Psychiatric Associates is a private practice of psychiatry consisting of about 25 psychiatrists, psychiatric nurse practitioners and psychotherapists with physical locations in Philadelphia and Paoli, PA and serving all of PA, NJ, NY and FL virtually via HIPAA compliant tele-psychiatry. Individuals seeking not only evaluations but long-term psychiatric care, can contact Rittenhouse Psychiatric Associates directly.
These videos aim to increase awareness and discussion of mental health topics and to encourage struggling individuals to schedule an appointment directly with a mental health provider. Mental health needs to be normalized, and simply speaking about mental health topics openly, is an important first step.
Dr. Pagnani and Rittenhouse Psychiatric Associates are NOT advocating for or against the use of any mentioned psychiatric medications for any specific individual. Additionally, any side effects mentioned are not a complete list of potential side effects or contraindications to taking any mentioned medications, and all risks and benefits of a medication should be discussed with an individual’s provider at an appointment, before starting, stopping or making changes to a medication regimen.
This video is INFORMATIVE ONLY - NOT MEDICAL ADVICE.
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In this episode, I discuss a medication known as olanzapine (Zyprexa).
My book is now available! It discusses my experience with Bipolar Disorder.
The Fifth Episode - Inside The Manic Mind.
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Intro Created by Leah Leblanc - leahleblanc.com
For information purposes only!