Cymbalta Side Effects

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Cymbalta (Duloxetine) for ADHD Side Effects 0 Views • 4 months ago

Main Chapters:
00:00 Intro - Cymbalta (Duloxetine) for ADHD
00:12 Take home message
01:54 How do Serotonin Norepinephrine Reuptake Inhibitors work? (SNRIs)
08:09 First SNRIs Venlafaxine (Effexor) / Desvenlafaxine (Pristiq)
11:41 Duloxetine (Cymbalta)
15:46 Milnacipran (Savella) / Levomilnacipran (Fetzima)
17:37 Cymbalta for ADHD
28:12 Conclusion
30:32 Questions

Duloxetine (Cymbalta) is a relatively balanced serotonin/norepinephrine reuptake inhibitor (SNRI), approved for depression, fibromyalgia, and a number of chronic pain syndromes. It is used off label for ADHD. Only a few studies support its efficacy in treating ADHD in children and adults.

Other relatively pure norepinephrine reuptake inhibitors (atomoxetine/Strattera), and SNRI (venlafaxine/Effexor, milnacipran/Savella/Fetzima, tricyclic antidepressants) have been shown to reduce both inattentive and hyperactive/impulsive symptoms of ADHD.

I tend to use far more duloxetine for treating ADHD than these other options, because the side effects of duloxetine tend to be more tolerable, predictable, and safer than those with the other SNRI AND NRI. This is a generalization, and there are certainly individuals who do not have good responses to duloxetine or have great responses to these other agents.

Overdoses (which can be fatal) with tricyclics can occur at doses only slightly above the therapeutic range; most individuals have constipation, weight gain, lethargy, and cardiac side effects from this class of drugs. Venlafaxine often creates withdrawal effects with missed doses, and its norepinephrine action is relatively weak. Side effects with atomoxetine tend to be less predictable than those from duloxetine, and most individuals need to titrate upwards for weeks before reaching effective doses. In the US, milnacipran is not available as a generic, making prohibitively expensive for many.

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Free link to my Medium Article on Cymbalta (Duloxetine) for ADHD:
https://medium.com/wise-well/s....top-using-confusing-

Follow https://dockruse.medium.com on Medium for hundreds of full length articles on this subject and more!
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References:
Duloxetine May Improve Some Symptoms of Attention-Deficit/Hyperactivity Disorder (2010)
https://www.psychiatrist.com/p....cc/duloxetine-may-im

Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on attention and executive functions in patients with major depressive disorder (2010)
https://pubmed.ncbi.nlm.nih.gov/20385412/

Efficacy and Adverse Effects of Venlafaxine in Children and Adolescents with ADHD: A Systematic Review of Non-controlled and Controlled Trials (2013)
https://www.eurekaselect.com/article/49645

Serotonin Norepinephrine Reuptake Inhibitors: A Pharmacological Comparison (2014)
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC40083

Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents (2014)
https://www.cochranelibrary.co....m/cdsr/doi/10.1002/1

Full Chapter list:
00:00 Intro - Cymbalta (Duloxetine) for ADHD
00:12 Take home message
01:54 How do Serotonin Norepinephrine Reuptake Inhibitors work? (SNRIs)
03:39 Comparing Serotonin Reuptake Inhibitors (SSRIs) and SNRIs
04:06 SSRIs and SNRIs Side Effects
06:58 Different Effects between SSRIs and SNRIs
08:09 First SNRIs Venlafaxine (Effexor) / Desvenlafaxine (Pristiq)
11:41 Duloxetine (Cymbalta)
13:02 Cymbalta Effects and Side Effects
15:46 Milnacipran (Savella) / Levomilnacipran (Fetzima)
17:37 Cymbalta for ADHD
18:53 Cymbalta Compared to Strattera (Atomexetine)
20:47 Cymbalta Compared to Tricyclic Antidepressants (TCAs)
26:00 Inhibitory Constant (KI) / Relative Potency / Transporter Binding
28:12 Conclusion
30:32 Questions
30:43 Increasing the Size of the Hippocampus
33:36 Sertraline for ADHD
35:32 Luvox (Fluvoxamine)
37:21 Outro

Streamed live May 15, 2024

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Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions. Subscribe if you're curious about how neuro-atypical brains can optimize their functioning in our shared, and somewhat strange, world.

Dr. Kruse has posted talks in both the "live" and the "video" sections of this channel. Thumbnails on ADHD topics have a pink background, and those on more general mental health topics have a purple background. A small collection of ADHD-Trump videos have an orange background.

You're welcome to email him with topics you want discussed or people you think he should interview.

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#health #mentalhealth #adhd #cymbalta

What is Duloxetine? London Pain Clinic Side Effects 0 Views • 4 months ago

Duloxetine is a medication in the class of anti-depressant drugs, used to treat major depression and provide relief from nerve pain or peripheral neuropathy in diabetics. It belongs to a class of medicines called the selective serotonin and norepinephrine reuptake inhibitors (SSNRIs).

Originally produced by Lilly researchers, Duloxetine hydrochloride was patented in 1981 and was approved for use by the Food and Drug Administration (FDA) in 2004. The drug is sold under the drug name Cymbalta and is officially prescribed for the following purposes:

Major Depressive Disorder Diabetic Peripheral Neuropathic Pain

http://www.londonpainclinic.co....m/antineuropathic-me

As a consultant in pain medicine at the Imperial Healthcare NHS Trust in London and Medical Director of the London Pain Clinic http://www.londonpainclinic.com/ , Dr Chris Jenner works daily with patients who suffer from some of the most common, painful and yet misunderstood conditions to affect people around the world today.

Alongside a raft of professional qualifications and more than 15 years’ experience in the specialised field of pain medicine, Dr Jenner possesses a true passion for his subject, a fact which is not only evident through his commitment to using the very best cutting-edge treatments, but also through his desire to understand the impact of acute and chronic pain on the everyday lives of his patients.

Dr Jenner’s experience in treating conditions such as spinal pain, fibromyalgia and arthritis has led him to become one of the leading authorities in his field. Using a holistic approach and a variety of treatments which typically combine medication with minimally-invasive pain management procedures, he works with his patients to restore a pain-free existence, higher levels of physical function and a vastly improved quality of life.
Dr Jenner has several published books on related conditions, you can purchase them from Amazon on the below Links.

Arthritis: A practical guide to getting on with your life (How to Self-Help Guide)
https://www.amazon.co.uk/gp/product/1845284712?keywords=dr%20chris%20jenner&qid=1457818154&ref_=sr_1_2&sr=8-2
Fibromyalgia and Myofascial Pain Syndrome: A self-help guide
https://www.amazon.co.uk/gp/product/1845284674?keywords=dr%20chris%20jenner&qid=1457818142&ref_=sr_1_1&sr=8-1
Neck and Back Pain: A self-help guide (How to Self-Help Guide)
https://www.amazon.co.uk/gp/product/1845284682?keywords=dr%20chris%20jenner&qid=1457818154&ref_=sr_1_3&sr=8-3

Cymbalta (duloxetine) Side Effects 1 Views • 4 months ago

Dr. Pagnani of Rittenhouse Psychiatric Associates discusses Cymbalta (duloxetine) an SNRI (selective serotonin norepinephrine reuptake inhibitor) which increases availability of both serotonin and norepinephrine in the synaptic cleft and is often used to treat depression, anxiety and chronic pain conditions.

Dr. Pagnani is the founder and medical director of Rittenhouse Psychiatric Associates, an Instructor at The Johns Hopkins Hospital for the Department of Psychiatry, he supervises psychiatric residents at Jefferson Hospital, he serves on the Young Professional Board of Uplift, the Center for Grieving Children and he maintains a private practice of Psychiatry in Philadelphia where he sees patients for one-time psychiatric evaluations and second opinions. He is a licensed physician and surgeon in NJ, PA, NY, MD, DE, FL and CA and can provide consultations to individuals via HIPAA compliant Telehealth visits living in these locations.

Rittenhouse Psychiatric Associates is a private practice of psychiatry consisting of about 25 psychiatrists, psychiatric nurse practitioners and psychotherapists with physical locations in Philadelphia and Paoli, PA and serving all of PA, NJ, NY and FL virtually via HIPAA compliant tele-psychiatry. Individuals seeking not only evaluations but long-term psychiatric care, can contact Rittenhouse Psychiatric Associates directly.

These videos aim to increase awareness and discussion of mental health topics and to encourage struggling individuals to schedule an appointment directly with a mental health provider. Mental health needs to be normalized, and simply speaking about mental health topics openly, is an important first step.

Dr. Pagnani and Rittenhouse Psychiatric Associates are NOT advocating for or against the use of any mentioned psychiatric medications for any specific individual. Additionally, any side effects mentioned are not a complete list of potential side effects or contraindications to taking any mentioned medications, and all risks and benefits of a medication should be discussed with an individual’s provider at an appointment, before starting, stopping or making changes to a medication regimen.

This video is INFORMATIVE ONLY - NOT MEDICAL ADVICE.

If you are researching a specific topic, please view our Youtube channel, click all videos and use the search function. Please also visit and follow us on instagram and FB: @RittenhousePsych.

www.RittenhousePA.com
www.ChrisPagnaniMD.com

Cymbalta and Chronic Pain Side Effects 1 Views • 4 months ago

Dr. Pagnani of Rittenhouse Psychiatric Associates discusses Cymbalta (duloxetine) and its use in treating certain chronic pain conditions, regardless of whether a patient has a history of an anxiety or mood disorder. This medication (like all antidepressant medications) has the potential for various side effects (some serious) and if someone is considering a medication trial, it is vital that they make an appointment with a mental health professional.

Dr. Pagnani is the founder and medical director of Rittenhouse Psychiatric Associates, an Instructor at The Johns Hopkins Hospital for the Department of Psychiatry, he supervises psychiatric residents at Jefferson Hospital, he serves on the Young Professional Board of Uplift, the Center for Grieving Children and he maintains a private practice of Psychiatry in Philadelphia where he sees patients for one-time psychiatric evaluations and second opinions. He is a licensed physician and surgeon in NJ, PA, NY, MD, DE, FL and CA and can provide consultations to individuals via HIPAA compliant Telehealth visits living in these locations.

Rittenhouse Psychiatric Associates is a private practice of psychiatry consisting of about 25 psychiatrists, psychiatric nurse practitioners and psychotherapists with physical locations in Philadelphia and Paoli, PA and serving all of PA, NJ, NY and FL virtually via HIPAA compliant tele-psychiatry. Individuals seeking not only evaluations but long-term psychiatric care, can contact Rittenhouse Psychiatric Associates directly.

These videos aim to increase awareness and discussion of mental health topics and to encourage struggling individuals to schedule an appointment directly with a mental health provider. Mental health needs to be normalized, and simply speaking about mental health topics openly, is an important first step.

Dr. Pagnani and Rittenhouse Psychiatric Associates are NOT advocating for or against the use of any mentioned psychiatric medications for any specific individual. Additionally, any side effects mentioned are not a complete list of potential side effects or contraindications to taking any mentioned medications, and all risks and benefits of a medication should be discussed with an individual’s provider at an appointment, before starting, stopping or making changes to a medication regimen.

This video is INFORMATIVE ONLY - NOT MEDICAL ADVICE.

If you are researching a specific topic, please view our Youtube channel, click all videos and use the search function. Please also visit and follow us on instagram and FB: @RittenhousePsych.

www.RittenhousePA.com
www.ChrisPagnaniMD.com

What is Cymbalta good for? Cymbalta side effects in elderly Side Effects 1 Views • 4 months ago

I want to talk to you today about Cymbalta, that’s Duloxetine. So what is Cymbalta good for? It is used to treat depression and anxiety, and right now, seems to be the flavor of the month and the most popular treatment for pain.

The issue is there are high doses being prescribed and Cymbalta can have side effects in elderly. In high doses Cymbalta can make people angry, paranoid, and not sleep, unfortunately, they attribute that behavior to depression or dementia, and then they give more - which is the exact opposite of what needs to happen.

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Long-Term Effects Of Cymbalta Side Effects 1 Views • 4 months ago

0:00 Intro
0:16 Can You Ber On Cymbalta Long-Term?
0:41 What Does Cymbalta Do To The Brain?
1:47 Does Cymbalta Change You Personality?
2:36 Is Cymbalta Hard To Get Off Of?

6:20 What Are The Long Term Effects Of Cymbalta?

(View Article Here: https://www.alternativetomeds.....com/blog/long-term-e

7:35 How Long Should You Stay On Cymbalta?
8:10 What Are The Most Common Side Effects Of Cymbalta?
10:16 What Are The Less Common Side Effects?
10:44 Are Cymbalta Side Effects Permanent?

12:30 Can Duloxetine Be Taken Long-Term?

(Study mentioned: https://link.springer.com/arti....cle/10.1186/1471-231

13:54 Is Cymbalta Worth The risk?

(https://www.aboutlawsuits.com/....cymbalta-should-not-

15:33 What Is A Good Replacement For Cymbalta?

16:58 Outro

Across the globe, doctors write prescriptions to patients without informing them what the long-term effects of Cymbalta are, or what will happen when discontinuing Cymbalta. The medication is given for a wide range of symptoms — from depression to pain from nerve damage.
Cymbalta has developed a reputation for being a medication that is very difficult to stop using. The symptoms experienced by long-term users of Cymbalta can make life unbearable at times. And when a person decides to quit Cymbalta, for some, the reactions can be pretty painful.

Side effects of Cymbalta include:
Addiction
Withdrawal effects
Seizures
Leg cramps, muscle spasms
Suicidality
Viral infection
Liver damage
Fractures
Bleeding Disorders
Sleep Disorders
Diabetes Mellitus
Agitation
“Feeling not like myself”
“Feeling foggy and detached”
Reduction in positive feelings
Emotional blunting
Fatigue
Somnolence (daytime sleepiness)
Headache
Low sex drive, sexual dysfunction
Weight loss, weight gain
Blood pressure issues
Cardiac issues
Profuse sweating
Constipation
Diarrhea

How to Discontinue Cymbalta Safely
Cymbalta (duloxetine) is a medication that is usually given to treat issues of depression. Regardless of the reason for being prescribed Cymbalta, it’s important that when an individual decides to discontinue any medication, they are also incorporating an alternative treatment to address any underlying issues.

Cymbalta brain zaps, dizziness, nausea, brain zaps, and fatigue are other commonly reported Cymbalta withdrawal effects. Cymbalta withdrawal may be experienced either when attempting to discontinue Cymbalta or, in some cases, in between doses — known as interdose withdrawal. Interdose-withdrawal most commonly occurs where drugs have a relatively short half-life, and withdrawal symptoms can emerge some hours after a dose is taken.

So many people have been negatively affected by quitting Cymbalta that the term Cymbalta Discontinuation Syndrome is used commonly to classify the symptoms associated with withdrawal. If the symptoms become too much to handle at home, many attend healing centers for Cymbalta withdrawal.

Cymbalta is an SNRI (serotonin-norepinephrine reuptake inhibitor). For those who are reliant on Cymbalta long-term, the possibility of a serotonin deficiency exists. In order to effectively treat any long-term effects of Cymbalta, focusing on potential underlying causes is important. Reviewing potential underlying causes with a specialist can also help to ensure the treatment plan is accurate to address individual needs and characteristics.

An investigation to determine any underlying causes that may be contributing to an individual’s symptoms should include questions such as:

Have hormones and nutritional elements been tested for deficiencies?
Has the diet been upgraded sufficiently?
Have alcohol and recreational drugs been ruled out or discontinued?
Have food allergies been tested for that could be causing psychiatric or physical symptoms?
Has situational stress contributed to symptoms? Has counseling such as CBT been utilized?
Is there an accumulation of neurotoxins, such as heavy metals, which are contributing to symptoms such as anxiety, psychosis, or depression?
By reviewing factors such as these and others, with a professional, the individual is able to pinpoint and resolve or eliminate many obstacles to wellness.

For More Information About Cymbalta and it's side effects Please Visit :
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Duloxetine (Cymbalta) side effects: 16 TIPS to AVOID side effects! Side Effects 0 Views • 4 months ago

This video examines the antidepressant Duloxetine and its side effects.Duloxetine is a prescription medicine. The brand name is Cymbalta.
Cymbalta belongs to a class of medicines known as SNRIs (or serotonin-norepinephrine reuptake inhibitors).

Read entire transcript here: https://drthinkyourhealth.com/....duloxetine-side-effe

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00:00 Intro
00:05 What is Duloxetine side effects?
00:21 What is it used for?
00:50 How to take Duloxetine?
01:14 What dose should you start at?
01:53 Duloxetine side effects? 16 Tips to avoid side effects
02:56 Serotonin Syndrome
04:18 Discontinuation syndrome
05:21 Duloxetine eye problems

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Sources:
1)https://www.uptodate.com/contents/duloxetine-drug-information?search=cymbalta&source=panel_search_result&selectedTitle=1~106&usage_type=panel&kp_tab=drug_general&display_rank=1
2)https://www.rxlist.com/cymbalta-drug.htm
3)https://www.accessdata.fda.gov..../drugsatfda_docs/lab

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Cymbalta Side Effects

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