Edward Gerstenfeld, MD, FACC, Executive Editor of JACC: Clinical Electrophysiology interviews Jeff Healey, MD about Apixaban versus Aspirin according to CHA2DS2-VASc score in Subclinical Atrial Fibrillation: Insights from ARTESiA. This paper was simultaneously published in JACC to coincide with research presented during HRS 2024.

How does Eliquis work?.
Eliquis is a type of anticoagulant medication that works by inhibiting the activity of a blood clotting protein called Factor Xa. This protein is responsible for the formation of blood clots, and by inhibiting its activity, Eliquis helps to prevent the formation of these clots. Unlike other anticoagulants, such as warfarin, Eliquis does not require regular blood tests to monitor its effectiveness. This is because Eliquis has a predictable and consistent effect, which means that the dosage can be easily adjusted based on the patient's age, weight, and medical history.
Eliquis is taken orally, and it is rapidly absorbed into the bloodstream. It has a half-life of approximately 12 hours, which means that it stays in the body for a relatively short period of time. This makes it a good option for patients who need to undergo surgery or other invasive procedures, as it can be discontinued quickly and does not require a lengthy waiting period before the procedure can be performed.
Overall, Eliquis is a highly effective anticoagulant medication that can help to prevent blood clots and strokes in patients with a variety of medical conditions.
Benefits of using Eliquis.
There are several benefits to using Eliquis as an anticoagulant medication. One of the main benefits is that it is highly effective at preventing blood clots and strokes, making it a valuable treatment option for patients who are at risk of these conditions. Additionally, Eliquis has a lower risk of causing bleeding complications than other anticoagulants, such as warfarin. This is because Eliquis has a more targeted effect on Factor Xa, which means that it is less likely to interfere with other blood clotting proteins.
Comparison with other anticoagulants.
Eliquis is just one of several anticoagulant medications that are available on the market today. Other commonly used anticoagulants include warfarin, dabigatran, and rivaroxaban. While all of these medications work by inhibiting blood clotting proteins, there are some key differences between them.
One of the main differences between Eliquis and warfarin is that Eliquis does not require regular blood tests to monitor its effectiveness. Warfarin, on the other hand, does require regular blood tests to ensure that the patient is receiving the appropriate dose. Additionally, warfarin has a higher risk of causing bleeding complications than Eliquis, which can be a significant disadvantage for some patients.
Usage and dosage of Eliquis.
Eliquis is typically prescribed for patients who are at risk of blood clots and strokes due to medical conditions such as atrial fibrillation, deep vein thrombosis, or pulmonary embolism. The dosage of Eliquis can vary depending on the patient's age, weight, and medical history, but it is typically taken twice a day in 2.5mg or 5mg doses.
It is important to follow the dosage instructions provided by your healthcare provider carefully, as taking too much or too little of the medication can have serious consequences. Additionally, it is important to continue taking the medication as prescribed, even if you feel better, as stopping the medication prematurely can increase the risk of blood clots and strokes.
Side effects of Eliquis.
Like all medications, Eliquis can cause side effects in some patients. The most common side effect of Eliquis is bleeding, which can occur in any part of the body. This can be a serious complication, especially if the bleeding is severe or occurs in a critical area such as the brain. Other side effects of Eliquis can include nausea, fatigue, and headache.
If you experience any side effects while taking Eliquis, it is important to notify your healthcare provider immediately. They may need to adjust your dosage or switch you to a different medication to help manage your symptoms.
Precautions before taking Eliquis.
Before taking Eliquis, it is important to inform your healthcare provider of any medical conditions you may have, as well as any medications or supplements you are taking. This can help to prevent drug interactions and ensure that Eliquis is safe and effective for you to take.
Additionally, it is important to avoid activities that can increase your risk of bleeding while taking Eliquis. This can include activities such as contact sports or heavy lifting.
"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.



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Wondering if Eliquis is safe? Questions on how to take Eliquis? You're in the right spot.

Today I discuss the ins and outs of Eliquis which is the brand name for apixaban. I discuss what Eliquis (apixaban) is prescribed for, how it works, how to take Eliquis (apixaban), side effects and monitoring, and how long to take Eliquis (apixaban).

It has been several years since eliquis was approved as an oral anticoagulant but still more research is being done to show its benefits in helping patients with non-valvular atrial fibrillation.

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While warfarin has long been a common treatment option for patients with atrial fibrillation new medications are coming to the market which provide different benefits than the original option.

Alcohol intake can affect how the body metabolizes certain medications. Patients undergoing medication therapy should avoid drinking alcohol on a daily basis. Alcohol should be limited to no more than 1 to 2 servings of alcohol occasionally. The antiplatelet effect of alcohol increases the risk of major bleeding, even if the INR remains within the target range.

In this video, Jennifer Friend, ANP, from Henrico Cardiology Associates, discusses the role alcohol can play in magnifying the effect of blood-thinning medications, commonly prescribed for heart problems. For more information, contact Henrico Cardiology Associates at 804-288-0134 or visit henricocardiology.com.

Researchers at University of Michigan Health found that taking aspirin and another blood thinner may be harmful for some people.

There are a number of side effects associated with Eliquis, but they are usually mild and tend to go away after you have been taking the drug for a while.

Eliquis is a prescription blood thinner that's used to prevent stroke and heart attack in people with atrial fibrillation, a type of irregular heartbeat. Eliquis belongs to a drug class called oral anticoagulants, which work by preventing blood from clotting to keep it flowing smoothly through the body.

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Blood thinners are medicines that prevent blood clots from forming. They do not break up clots that you already have. But they can stop those clots from getting bigger. It's important to treat blood clots, because clots in your blood vessels and heart can cause heart attacks, strokes, and blockages.
Who needs blood thinners?

You may need a blood thinner if you have:

Certain heart or blood vessel diseases
An abnormal heart rhythm called atrial fibrillation
A heart valve replacement
A risk of blood clots after surgery
Congenital heart defects

What are the different types of blood thinners?

There are different types of blood thinners:

Anticoagulants, such as heparin or warfarin (also called Coumadin), slow down your body's process of making clots.
Antiplatelets, such as aspirin and clopidogrel, prevent blood cells called platelets from clumping together to form a clot. Antiplatelets are mainly taken by people who have had a heart attack or stroke.

How can I take blood thinners safely?

When you take a blood thinner, follow the directions carefully. Blood thinners may interact with certain foods, medicines, vitamins, and alcohol. Make sure that your health care provider knows all of the medicines and supplements you are using.

You may need regular blood tests to check how well your blood is clotting. It is important to make sure that you're taking enough medicine to prevent clots, but not so much that it causes bleeding.
What are the side effects of blood thinners?

Bleeding is the most common side effect of blood thinners. They can also cause an upset stomach, nausea, and diarrhea.

Other possible side effects can depend on which type of blood thinner that you are taking.

Understanding my medicine: anticoagulants for atrial firbilation.

This video explains the common side effects of anticoagulant medicuine and what to do if you experience them.