Naloxone Side Effects


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0:00 What’s the difference between Naloxone and Naltrexone?
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Critical Role of Naloxone in Toxicological Emergencies
Welcome to Doc A T, your trusted source for high-yield medical lectures! In this detailed session, we dive deep into toxicological emergencies, focusing on the life-saving role of Naloxone in opioid overdoses. Whether you're a doctor, medical student, or preparing for exams like USMLE, PLAB, AMC, NEET PG, or FCPs, this lecture is packed with essential knowledge to boost your understanding and exam performance.
🔍 What You’ll Learn in This Video:
✅ Overview of toxicological emergencies and their clinical presentations
✅ Mechanism of action and pharmacology of Naloxone
✅ Indications, dosing, and administration routes for Naloxone
✅ Recognizing and managing opioid overdoses effectively
✅ Case-based discussions to enhance clinical decision-making
🎯 Perfect for:
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91 Americans die every day from an opioid overdose. Naloxone can help. Learn more about this life saving medicine in this short video.
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TRANSCRIPT:
What is naloxone? It is an effective medication used to treat an opioid overdose. It is sold under the name Narcan. It is designed to reverse and block the effects of opioids. It quickly restores normal respiration to the individual who is overdosing.
It can be administered by injection or nasal spray. It should be administered by a healthcare professional, emergency medical provider, or trained personnel. People who are given naloxone should still seek medical attention. Most common side effects of naloxone include swelling of hands or face, nausea, vomiting, fever, and irritability.
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OTHER HELPFUL VIDEOS:
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https://youtu.be/dAw9OXzEnEo


This animation has been created for people prescribed opioids for chronic pain, or anyone interested in learning more about prescription opioid safety. Naloxone is a life-saving medicine that reverses the effects of opioids in case of an emergency, while you wait for an ambulance.
If you'd like to know more about opioid safety or naloxone, speak with your pharmacist or GP, and see the 'maximising opioid safety' leaflet here:
https://www.turningpoint.org.a....u/research/engage/na


Visit https://end-overdose-epidemic.org for more information on AMA’s efforts to end the overdose epidemic.
Bobby Mukkamala, MD, chair of the AMA Substance Use and Pain Care Task Force, joins to discuss what FDA's recent approval of OTC naloxone means for doctors and patients—as well as how to administer Narcan in an emergency. The life-saving medication can reverse an overdose from fentanyl, oxycodone and other opioids. American Medical Association CXO Todd Unger hosts.
Access "Substance Use Disorders and Addiction Education to Meet New DEA Requirements" training via AMA Ed Hub™ , here: https://edhub.ama-assn.org/course/302
Use the link above to get Continuing Medical Education (CME) credit and satisfy new requirements issued by the DEA to meet conditions of the MATE Act for physicians and practitioners on treating and managing patients with opioid or other substance use disorders.
Stay up to date on all the latest advocacy news by subscribing to AMA Advocacy Update: https://www.ama-assn.org/advocacy-news
00:00 AMA Update for April 26, 2023
00:41 Over-the-counter Narcan (OTC naloxone)
00:46 Over-the-counter naloxone nasal spray approved by #FDA
01:10 Naloxone uses
01:24 Where to buy Narcan nasal spray
02:17 Is naloxone safe?
02:34 How to use naloxone
03:10 Fentanyl and xylazine overdoses
03:46 Naloxone side effects: giving someone Narcan who doesn't need it
04:14 Carrying #narcan - should you carry naloxone?
04:37 Narcan prices: How much is a naloxone kit?
05:16 Understanding opioid use disorder (OUD), #naloxone access, #narcan stigma
06:24 Talking to patients about opioids and overdose risk
07:34 AMA's Substance Use and Pain Care Task Force
07:54 Physician resources, training and #CME credits available (link in description)
08:58 Treating substance use disorder (SUD)
Visit the AMA Update video page for more videos in this series: https://www.ama-assn.org/ama-update-videos.
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Naloxone is now available in many places without a prescription. Naloxone is a temporary antidote for overdoses from opioid drugs
Here are 5 things everyone should know about Naloxone.
Learn more about overdose awareness: https://www.addictionpolicy.org/overdose-awareness


(29 Apr 2016) Prince's final days and unexpected death at age 57 raise questions among experts familiar with prescription painkiller overdoses.
It's possible the innovative musician's demise represents one of the most public tragedies in an overdose crisis now gripping America.
A law enforcement official told The Associated Press on Thursday that investigators are looking into whether Prince died from an overdose and whether a doctor was prescribing him drugs in the weeks before he was found dead at his home in suburban Minneapolis. The law enforcement official has been briefed on the investigation and spoke to the AP on condition of anonymity because he was not authorized to speak to the media.
Whether Prince was addicted to painkillers is uncertain, but some are wondering whether the stigma surrounding addiction may have prevented Prince — who built a reputation as a sober superstar — from seeking help if he was becoming dependent.
Questions about Prince's health surfaced April 15, when his private plane made an emergency stop in Moline, Illinois. He was found unconscious aboard the aircraft, according to a law enforcement official who was briefed on the investigation and spoke to The Associated Press.
The official spoke on condition of anonymity because he was not authorized to speak to the media.
While the plane was on the tarmac, the person said, first-responders gave Prince a shot of Narcan, an antidote that is used to reverse suspected opioid overdoses. Opioids include oxycodone, Percocet, morphine, codeine and heroin.
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What Are The Side Effects Of Naloxone? In this informative video, we will discuss the side effects associated with naloxone, a medication that plays a vital role in reversing opioid overdoses. Understanding the potential side effects is essential for anyone involved in emergency situations or managing pain. We will cover common withdrawal symptoms that may occur in individuals who are dependent on opioids after naloxone administration. Additionally, we will touch on rare allergic reactions and other less frequent side effects that some individuals might experience.
Knowing how naloxone works and its implications in overdose scenarios is important for healthcare providers and pharmacists alike. We will highlight the significance of seeking medical assistance after administering naloxone, as its effects may not last long enough to prevent a subsequent overdose. Furthermore, we will discuss the accessibility of naloxone and its various forms, emphasizing the importance of having this lifesaving medication readily available.
Join us as we break down the essential information regarding naloxone and its side effects. Don't forget to subscribe to our channel for more helpful discussions on pain management and medication safety.
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#Naloxone #OpioidOverdose #PainManagement #WithdrawalSymptoms #EmergencyMedicine #HealthCare #MedicationSafety #AddictionRecovery #AllergicReactions #LifesavingMedication #OpioidCrisis #EmergencyResponse #Pharmacy #HealthEducation #MedicalAdvice
About Us: Welcome to Pain Medicine Network, your trusted source for comprehensive information on pain management and treatment options. Our channel is dedicated to exploring the latest advancements in pain medicine, offering insights into innovative therapies, research breakthroughs, and expert interviews.
Please note that our content is purely informational and should not be considered medical advice. Always consult a healthcare professional for personalized guidance and do your own due diligence when it comes to your health and treatment options. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.


Welcome to our channel! In this informative video, we're diving deep into the life-saving medication known as Naloxone. Whether you're a healthcare professional, or simply curious about this crucial tool in the fight against opioid overdose, this video is for you.
Naloxone, often referred to as Narcan, is a medication that can reverse the effects of opioid overdose within minutes. It's a critical tool in reducing opioid-related deaths and is increasingly available to the general public.
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** Pictures used in thubmanil of this video are licensed under creative commons licensing, details:
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* Left picture on the thumbnail credit: Intropin (Mark Oniffrey), CC BY-SA 4.0 https://creativecommons.org/licenses/by-sa/4.0, via Wikimedia Commons
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Video Chapters
0:00 Introduction
0:44 Overview
2:25 Pharmacokinetics
3:21 Mechanism of action
4:56 Therapeutic uses
6:45 How to treat opioid overdose
10:44 Adverse effects


Naloxone, also known by the brand name Narcan, is a medication that can be used to treat opioid overdose and substantially reduce the risk of death associated with opioid toxicity. In this video, I discuss the pharmacology of naloxone.
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TRANSCRIPT
Naloxone, also known by the brand name Narcan, is a medication that can be used to treat opioid overdose and substantially reduce the risk of death associated with opioid toxicity. The drug is a competitive antagonist at opioid receptors, which means that it works by binding to the same receptors that opioid drugs bind to, but instead of activating those receptors like opioid drugs, naloxone blocks activity at them. Naloxone also causes opioid drugs that are already attached to the receptor to be displaced. This combination of receptor blockade and removal of active opioid drugs makes naloxone capable of reversing an opioid overdose and reducing the risk of complications associated with one.
Naloxone is commonly administered by injection or nasal spray, but intranasal administration has become a preferred method due to its ease of use and safety. The drug typically begins working within a few minutes, with the exact time to onset being dependent on the route of administration. The effectiveness of naloxone can vary due to a number of factors, including the potency of the opioid in the patient’s system and the dose of opioids they administered. Repeated doses of naloxone are sometimes used to keep the patient from re-experiencing effects of opioids still present in their system after naloxone begins to wear off.
When naloxone is administered to someone with opioids in their system it can cause acute withdrawal symptoms due to the sudden cessation of activity at opioid receptors. While there is some risk associated with complications of acute withdrawal, it is considered low especially compared to the risk of complications linked to opioid overdose. Naloxone administered to someone who has not used opioids recently typically has little to no effect.
REFERENCES
Aziz R, Nguyen L, Ruhani W, Nguyen A, Zachariah B. The Optimal Initial Dose and Route of Naloxone Administration for Successful Opioid Reversal: A Systematic Literature Review. Cureus. 2024 Jan 21;16(1):e52671. doi: 10.7759/cureus.52671. PMID: 38380203; PMCID: PMC10878679.
Rzasa Lynn R, Galinkin JL. Naloxone dosage for opioid reversal: current evidence and clinical implications. Ther Adv Drug Saf. 2018 Jan;9(1):63-88. doi: 10.1177/2042098617744161. Epub 2017 Dec 13. PMID: 29318006; PMCID: PMC5753997.
Saari TI, Strang J, Dale O. Clinical Pharmacokinetics and Pharmacodynamics of Naloxone. Clin Pharmacokinet. 2024 Apr;63(4):397-422. doi: 10.1007/s40262-024-01355-6. Epub 2024 Mar 14. PMID: 38485851; PMCID: PMC11052794.
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Naloxone is an opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection.
In this video, let’s find found:
What is naloxone?
What is naloxone used for?
Contraindication
What are the side effects of taking naloxone?
How does naloxone work?
How to use naloxone?
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Tags: he-info, naloxone, naloxone tablet, naloxone uses, naloxone contraindication, naloxone side effects, naloxone mechanism, naloxone mechanism of action, naloxone indication, euphoria, Narcan, naloxone scrim, naloxone hydrochloride, naloxone hydrochloride injection, naloxone being used, naloxone kit, naloxone antagonist, administration naloxone, naloxone vending machine, naloxone nasal spray, buprenorphine naloxone, naloxone vs naltrexone, naloxone vs narcan, naloxone administration, naloxone dose, naloxone adverse effects, Zimhi


How Long Do Naloxone Side Effects Last? In this informative video, we discuss the important aspects of naloxone, a medication that plays a critical role in reversing opioid overdoses. We will cover how naloxone works, the duration of its effects, and the potential side effects that may arise after administration. Understanding naloxone's timeline and its impact on opioid receptors in the brain is essential for anyone involved in pain management or overdose prevention.
We will also highlight the common side effects associated with naloxone and what to expect after its use. While many side effects are mild and temporary, we will touch upon some serious reactions that could occur, emphasizing the importance of seeking medical attention if they arise.
This video aims to equip viewers with the knowledge necessary to handle opioid overdose situations effectively. We encourage everyone to get trained in naloxone administration and to always consult healthcare professionals for tailored guidance. Join us as we navigate this critical topic and help spread awareness about the life-saving potential of naloxone. Don’t forget to subscribe to our channel for more helpful discussions on pain medicine and management.
⬇️ Subscribe to our channel for more valuable insights.
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#Naloxone #OpioidOverdose #PainManagement #OpioidCrisis #DrugSafety #MedicationManagement #AddictionAwareness #HealthEducation #EmergencyCare #WithdrawalSymptoms #MedicalTraining #OverdosePrevention #HealthResources #PatientSafety #SubstanceUseDisorder
About Us: Welcome to Pain Medicine Network, your trusted source for comprehensive information on pain management and treatment options. Our channel is dedicated to exploring the latest advancements in pain medicine, offering insights into innovative therapies, research breakthroughs, and expert interviews.
Please note that our content is purely informational and should not be considered medical advice. Always consult a healthcare professional for personalized guidance and do your own due diligence when it comes to your health and treatment options. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.


In this episode, I discuss a medication known as naloxone (Narcan, Evzio).
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