A new treatment for severe hypoglycemia in diabetic patients

A new treatment for severe hypoglycemia in diabetic patients - Xeris pharma’s Gvoke (glucagon pen)

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Hypoglycemia is most common among people who take insulin, but it can also occur if you're taking certain oral diabetes medications.

Signs of severe hypoglycemia ranges from Confusion and disorientation, to Convulsions / fitting / seizures, Intense nightmares whilst asleep, Loss of consciousness and Coma.
Glucagon is a peptide hormone, produced by alpha cells of the pancreas. Glucagon increases blood sugar levels in the body by stimulating the liver to release stored glucose into the bloodstream.

It has the opposite effect of insulin, which lowers blood sugar levels.

Until now, people suffering from a severe hypoglycemic episode had to be treated with a glucagon injection that first had to be mixed in a several-step process.

Injectable glucagon has been approved for use in the U.S. for several decades and is commonly used by health care professionals for treating severe hypoglycemia.

On 10 Sep 2019, FDA approves Xeris Pharmaceuticals Inc’s Gvoke to treat severely low sugar levels in diabetes patients.

Gvoke, Xeris’ glucagon pen is an pre-filled device with liquid stable form of glucagon. It won approval for use in diabetes patients, aged 2 years and above.

This new way to administer glucagon may simplify the process, which can be critical during an episode and simplify the treatment.

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