What is Acalabrutinib? and What is Acalabrutinib used for?

Brand name of acalabrutinib is Calquence.
Acalabrutinib is used to treat people with mantle cell lymphoma (MCL; a fast-growing cancer that begins in the cells of the immune system) who have already been treated with at least one other chemotherapy medication.
It is also used alone or with obinutuzumab (Gazyva) to treat chronic lymphocytic leukemia (CLL; a type of cancer that begins in the white blood cells) and small lymphocytic lymphoma (SLL: a type of cancer that begins in the white blood cells).
Acalabrutinib is in a class of medications called kinase inhibitors.
It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.

How to use Acalabrutinib?

Acalabrutinib comes as a capsule to take by mouth. It is usually taken with or without food every 12 hours (twice a day) for as long as your doctor recommends that you receive treatment.
Take acalabrutinib at around the same times every day.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Take acalabrutinib exactly as directed.
Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the capsules whole with a glass of water; do not open, chew, or break them.

Your doctor may temporarily or permanently stop your treatment or decrease your dose of acalabrutinib depending on the side effects that you experience. Be sure to talk to your doctor about how you are feeling during your treatment. Do not stop taking acalabrutinib without talking to your doctor.

Whaen to take Acalabrutinib?

Before taking acalabrutinib,

tell your doctor and pharmacist if you are allergic to acalabrutinib, any other medications, or any of the ingredients in acalabrutinib capsules.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.

if you are taking cimetidine (Tagamet), famotidine (Pepcid, in Duexis), nizatidine (Axid), or ranitidine (Zantac) take acalabrutinib at least 2 hours before taking these medications.

if you are taking antacids (Maalox, Mylanta, Tums, others) take acalabrutinib at least 2 hours before or after taking these medications.

tell your doctor if you have an infection or have had surgery recently, or if you have or have ever had liver disease including hepatitis B, problems with your heart rhythm, or bleeding problems.

tell your doctor if you are pregnant or plan to become pregnant.
You should not become pregnant while you are taking acalabrutinib.
You should not start taking acalabrutinib until a pregnancy test has shown that you are not pregnant and you should use birth control to prevent pregnancy during your treatment and for at least 1 week after your final dose.
Acalabrutinib may harm your unborn baby. If you become pregnant while taking acalabrutinib, call your doctor immediately.

tell your doctor if you are breastfeeding. Your doctor may tell you not to breastfeed during your treatment and for 2 weeks after your final dose.

if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking acalabrutinib.
Your doctor may tell you to stop taking acalabrutinib for a period of time before and after the surgery or procedure.

plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen.
Acalabrutinib may make your skin sensitive to the dangerous effects of the sunlight, and may increase your risk of developing skin cancer.

What side effects can Acalabrutinib cause?

Acalabrutinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

headache.
nausea.
vomiting.
constipation.
diarrhea.
abdominal pain.
rash.
light bruising or small red or purple spots on skin.
joint or muscle pain.
extreme tiredness.

0 Comments

Up next

Autoplay

AMITRIPTYLINE (ELAVIL) - PHARMACIST REVIEW - #69

0 Views . 08/29/25 Side Effects

Please note that if you are under 18, you won't be able to access this site.

Up next

ACALABRUTINIB, What is acalabrutinib used for, Acalabrutinib CALQUENCE review

Up next

Language