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Amiodarone (Cordarone): What is Amiodarone Used For? Uses, Dose, Side Effects, Mechanism of Action
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- This is lesson n# 130 in "A DRUG IN BRIEF" Series. In this video I'm gonna discuss almost all you need to know about Amiodarone 200 mg (Cordarone): What is Amiodarone Used For? Uses, Dose, Side Effects, Mechanism of Action
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- In 3 minutes you'll learn about:
- What is Amiodarone 200 mg (Cordarone)?
- First, let’s talk about Amiodarone mechanism of action, Amiodarone is primarily a class III antiarrhythmic. Like other antiarrhythmic agents of this class, amiodarone works primarily by blocking potassium rectifier currents, responsible for the repolarization of the heart during phase 3 of the cardiac action potential.
- This potassium channel-blocking effect results in increased action potential duration and a prolonged effective refractory period in cardiac myocytes. So myocyte excitability is decreased, preventing reentry mechanisms and ectopic foci from perpetuating tachyarrhythmias.
Unlike other class III agents, amiodarone also blocks beta-adrenergic receptors, calcium channels, and sodium channels.
- It is available as 100 mg and 200 mg tablets, and also available as injection.
- Amiodarone is used in the treatment of atrial or ventricular arrhythmias, specially the life-threatening, recurrent ventricular arrhythmias, that do not respond to other antiarrhythmic agents.
- Learn more about Amiodarone 200 mg (Cordarone) mechanism of action, uses, dosage, side effects, and precautions in this video...
- Video Chapters:
00:12 - Amiodarone Mechanism of Action
00:57 - Amiodarone Dosage Forms
01:04 - Amiodarone Uses
01:15 - Amiodarone Dose
01:48 - Amiodarone Side Effects and Contraindications
03:01 - Amiodarone Precautions
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