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Ampicillin Nursing Considerations, Side Effects and Mechanism of Action Pharmacology for Nurses
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• 08/17/25
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Side Effects
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Ampicillin
Generic Name: ampicillin
Trade Name: Principen
Indication: skin infections, soft tissue infections, otitis media, sinusitis, respiratory infections, GU infections, meningitis, septicemia
Action: bactericidal, broader spectrum than penicillin, binds to cell wall leading to bacterial cell death
Therapeutic Class: anti-infective
Pharmacologic Class: aminopenicillin
Nursing Considerations
contraindicated in penicillin allergy, use caution in renal insufficiency
may lead to seizures, diarrhea, anaphylaxes, super infection
assess for infection
monitor liver function tests
instruct patient on signs of super infection: fury over growth on tongue, vaginal itching, loose and foul smelling stool
pt should not use with oral contraceptive use.
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