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Antibiotics

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Official Ninja Nerd Website: https://ninjanerd.org

Ninja Nerds!
In this pharmacology lecture, Professor Zach Murphy provides a high-yield overview of Antibiotics, focusing on their mechanisms of action, bacterial coverage, and clinical applications. This lecture is designed to enhance your understanding of antimicrobial agents and their role in treating various infections.

We begin with an introduction to antibiotic classification, discussing the differences between bactericidal and bacteriostatic agents and the importance of the spectrum of activity. The lecture then delves into the major classes of antibiotics, including:
• Beta-lactams: Penicillins, Cephalosporins, Carbapenems, and Monobactams
• Glycopeptides: Vancomycin and others
• Protein synthesis inhibitors: Aminoglycosides, Tetracyclines, Macrolides, Clindamycin, Linezolid
• Fluoroquinolones: Mechanism and clinical use
• Folic acid pathway inhibitors: Sulfonamides and Trimethoprim
• Others: Metronidazole, Rifampin, and more

Each antibiotic class is explored in detail, covering:
• Mechanism of action: How the drug targets bacterial processes
• Bacterial coverage: Gram-positive, Gram-negative, anaerobes, and atypicals
• Clinical indications: Common infections treated
• Adverse effects: Notable side effects and toxicity
• Resistance mechanisms: How bacteria evade antibiotic action

Visual illustrations, diagrams, and comparison tables are used throughout the lecture to simplify complex mechanisms and help you confidently distinguish between antibiotic classes. Whether you’re building your foundational knowledge or refreshing key pharmacologic principles, this lecture will keep you engaged and learning.

Enjoy the lecture and support us below!

Table of Contents:
0:00 Lab
0:07 Antibiotics Introduction
0:57 Mechanism of Action
24:18 Bacterial Coverage
53:16 Empiric Antibiotics for Common Infections
1:12:27 Adverse Drug Reactions & Contraindications
1:33:40 Mechanisms of Antibiotic Resistance
1:55:26 Antibiotics Cases
2:17:26 Comment, Like, SUBSCRIBE!

Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health.

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#ninjanerd #antibiotics #pharmacology

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