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Apixaban (Eliquis) – Uses, Side Effects, Mechanism of Action, Dosage, Interactions, Warnings

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Apixaban (Eliquis) – Uses, Side Effects, Mechanism of Action, Dosage, Interactions, Warnings
Apixaban (Eliquis) is an oral anticoagulant used to prevent and treat blood clots, including stroke prevention in non-valvular atrial fibrillation, treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE), and postoperative DVT prophylaxis after hip or knee replacement. It works by selectively inhibiting Factor Xa, reducing thrombin generation and clot formation without the need for routine coagulation monitoring. Common side effects include bleeding, anemia, and nausea, while serious risks involve intracranial hemorrhage and severe gastrointestinal bleeding. Dosage varies by indication, with adjustments based on age, weight, and renal function. Apixaban interacts with CYP3A4 and P-gp modulators and increases bleeding risk when combined with antiplatelets or NSAIDs. Caution is advised in patients with bleeding tendencies, renal or hepatic impairment, and it is not recommended for those with prosthetic heart valves or during pregnancy unless benefits outweigh risks.
#Apixaban #Eliquis #Apixabanuses #Eliquisuses #Apixabansideeffects #Eliquissideeffects
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