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Azithromycin Nursing Considerations, Side Effects, and Mechanism of Action Pharmacology for Nurses

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Azithromycin
Generic Name: azithromycin

Trade Name: Zithromax

Indication: URI, chronic bronchitis, lower respiratory infections, otitis media, skin infections, various STIs, prevention of bacterial endocarditis, treatment of cystic fibrosis

Action: inhibits bacterial protein synthesis

Therapeutic Class: agents for atypical mycobacterium, anti-infectives

Pharmacologic Class: Macrolide

Nursing Considerations:
 may lead to pseudomembranous colitis, pain, diarrhea, nausea, Stevens-Johnson syndrome, angioedema
 may increase risks for warfarin toxicity
 monitor patient for signs of anaphylaxis
 instruct patient to notify physician for diarrhea, or blood or pus in stool
 instruct patient to take medication exactly as prescribed

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