✅ Breztri Aerosphere ✅ Produced By Dr Khalid Warraich ✅

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Side Effects

Subscribers

Breztri Aerosphere is a prescription inhaler used to treat chronic obstructive pulmonary disease (COPD) , a chronic lung disease that includes chronic bronchitis, emphysema, or both. It contains three active ingredients:
Budesonide – A corticosteroid that reduces inflammation in the lungs.
Glycopyrrolate – A long-acting muscarinic antagonist (LAMA) that helps relax airway muscles.
Formoterol fumarate – A long-acting beta agonist (LABA) that helps open the airways.
Breztri is used for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD), including:
Chronic bronchitis – Persistent inflammation of the airways.
Emphysema – Damage to the air sacs in the lungs.
It reduces inflammation in the airways (Budesonide).
Relaxes airway muscles to improve airflow (Glycopyrrolate).
Opens airways for easier breathing (Formoterol).
Mechanism of action
Each of the 3 ingredients in Breztri has a different mechanism of action. Budesonide helps to decrease inflammation in the lungs which can lead to breathing problems. Glycopyrrolate blocks the effects of acetylcholine (a neurotransmitter) in the lungs, which allows the airways to relax and widen, making breathing easier. Formoterol binds to and activates beta2-adrenergic receptors on the smooth muscle cells in the airways. This activation also allows the airways to relax and widen, making breathing easier. Formoterol has a long-lasting effect, typically lasting 12 hours or more, which provides sustained symptom relief throughout the day for COPD patients.

Breztri Aerosphere Dosage

Standard Dosage for COPD

Recommended dose: Two inhalations (puffs) twice daily

Time of use: Morning and evening (approximately 12 hours apart)

Inhaler strength: Each puff contains:

Budesonide 160 mcg.

Glycopyrrolate 9 mcg.

Formoterol fumarate 4.8 mcg.

Side Effects of Breztri Aerosphere

Like all medications, Breztri Aerosphere can cause side effects. These can be classified as common, serious, and rare.

Common Side Effects

These are usually mild but should be monitored:

Cough, Sore throat, Headache, Muscle cramps, Runny or stuffy nose, Nausea.

Serious Side Effects (Seek medical attention if these occur).

Pneumonia – Symptoms include fever, chills, chest pain, and increased phlegm.

Increased heart rate (tachycardia).

High blood sugar (hyperglycemia).

Low potassium levels – Can cause muscle weakness or irregular heartbeat.

Osteoporosis (bone thinning) with long-term use.

Eye problems – Glaucoma or cataracts may develop.

Paradoxical bronchospasm – Sudden breathing difficulty after inhaling.

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