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CLONIDINE [USES,SIDE EFFECTS & INTERACTIONS]
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• 08/18/25
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Side Effects
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This is an Alpha 2- Adrenergic agonist
Strong anti-hypertensive
Stimulates alfa– 2 receptors in the brain stem
Decreases activities or enhancing inhibitory neuron
Then decrease sympathetic outflow
Decrease peripheral resistance, low HR, low Bp
Pain signal transmission is presented at presynaptic and post junctional alfa 2 adrenoceptors, hence pain relief as epidural clonidine
Uses:
Hypertension
Insomnia
PTSD
DM neuropathy
RLS
TICS
ADHD
Smoking cessation
Migraine
Menopausal hot flashes
Anxiolytic
Alcohol withdrawal
Ulcerative colitis
Shivering post anesthesia
Hyperhidrosis
A-Fib
Pheochromocytoma diagnosis
Tardive dyskinesia
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