Clopidogrel is an anti platelet. It is prescribed by your doctor usually after you have suffered an acute coronary syndrome like an unstable angina where you have severe chest pain, heart attack, stroke, or have a condition called peripheral arterial disease where your leg is painful on walking or at rest.

Platelets are blood cells that help blood clot. These are important when you have an injury. However, too much clotting in the blood can block blood vessels in your heart to cause a heart attack and block the blood vessels in your brain to cause a stroke, this is where low-dose aspirin as antiplatelet comes into play.

Dependent on your condition, your doctor may pair up clopidogrel with aspirin. Instead of taking clopidogrel and aspirin separately, to reduce the cost, there are formulations where manufacturers combine both clopidogrel and aspirin into one tablet. If you are being prescribed clopidogrel and aspirin separately, Speak to your doctor about the combination formula

Clopidogrel is a prodrug, which means it has to be converted into its active form by an enzyme in the body called CYP2C19 before it can work. For some people, they are CYP2C19 poor metabolizers, it is harder for their body to convert Clopidogrel to its active form, thus clopidogrel will not be working properly. In this situation, the doctor will change the dosing of clopidogrel or change clopidogrel into something else. Approximately 2% of Caucasians, 4% of African Americans, and 14% of Chinese are CYP2C19 poor metabolizers. Your doctor may perform a test to identify if you are CYP2C19 poor metabolizers.

Before you start taking clopidogrel, make sure your doctor knows all medical conditions that you have, this includes any kidney, liver problems, any bleeding disorder, more in the video...

You need to also tell your doctor all the medicines that you are currently taking, more in the video...

How much to take
The usual dose of clopidogrel is one 75 mg tablet daily.
If you have acute coronary syndrome, you may receive a single starting dose of 300 mg and then continue at one 75 mg tablet daily.

How to take it
It does not matter if you take this medicine before or after food.
Swallow the tablet with a glass of water. Do not crush or chew the tablets. more in the video

While you are on Clopidogrel
if you are seeing a new doctor or dentist or starting a new medication prescribed by a doctor or dentist, tell them that you are on Clopidogrel. if you plan to have surgery, tell your surgeon and anesthetist, that you are on clopidogrel. more in the video...

Side effects
- abnormal bruising or bleeding
- abnormal nose bleeds
more in the video

Lifestyle Changes:
Now, if you are put on aspirin, it's a wake-up call, you need to have some lifestyle changes.
What you eat and how much you eat are important. Reducing fat and salt intake. Salt is commonly known as, Sodium the symbol is Na+ increases blood pressure, and many foods in the supermarket contain sodium. this includes your daily bread. So read the labels while you purchasing your groceries, to control how much salt you take in. It's a good idea to remove table salt from your dining table. An adult body only needs around 1 – 2g of salt (460 – 920mg sodium) per day to function. Licorice is also something that increases blood pressure, so avoid it.

If you are a smoker, quit smoking. if you drink too much alcohol, stop it. If you need help stopping these. contact your doctor. Exercises are important as well. Now if you just have a heart attack or stroke, speak to your doctor or cardiac rehabilitation team for advice on types of suitable exercises to begin. Follow your doctor’s advice and slowly build up your activity. and Remember, never hold your breath when lifting weights.

Let me know in the comments down below, what lifestyle changes have you made or plan to make, and what other videos can I make to help you improve your health.

I hope this video is of value to you. Thank you for watching. Please do subscribe and hit the notification button for more Health and Medication-related videos!

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Soonkie the pharmacist
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DISCLAIMER:
This video is for general information only and should not be used to diagnose or treat medical conditions. Pharmacist Soonkie has used all reasonable care in compiling the information but makes no warranty as to its accuracy. Always consult a doctor or other healthcare professional for diagnosis and treatment of medical conditions.

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