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Clopidogrel Nursing Considerations, Side Effects, and Mechanism of Action Pharmacology for Nurses
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• 08/18/25
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Clopidogrel
Generic Name: clopidogrel
Trade Name: Plavix
Indication: atherosclerotic events, MI, CVA, PVD, acute coronary syndrome
Action: inhibits platelet aggregation
Therapeutic Class: Antiplatelet agent
Pharmacologic Class: platelet aggregation inhibitors
Nursing Considerations:
may cause GI bleeding, neutropenia, hypercholesterolemia
may increase risk for bleeding in warfarin, aspirin, heparin
can increase risk for bleeding with garlic, ginkgo, ginger
monitor for signs of bleeding
monitor bleeding times
monitor CBC and platelet count
discontinue use 5-7 days before surgery
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