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Clopidogrel ( Plavix 75 mg ): What is Clopidogrel Used For, Dosage, Side Effects & Precautions?
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- This is lesson n# 64 in "A DRUG IN BRIEF" Series. In this video I'm gonna discuss almost all you need to know about Clopidogrel ( Plavix 75 mg ): What is Clopidogrel Used For, Dosage, Side Effects, Precautions and mechanism of action
- In 3 minutes you'll learn:
- What is Clopidogrel ( Plavix 75 mg )?
- Clopidogrel is an antiplatelet agent. The active metabolite of clopidogrel selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet P2Y12 receptor and the subsequent ADP- mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation. This action is irreversible.
- It is available as 75 mg tablets.
- Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease). It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent).
- The usual dosage of Clopidogrel
Recent MI, Recent Stroke, or Established Peripheral Arterial Disease: PO 75 mg once daily with or without food. Acute Coronary Syndrome (Unstable Angina/Non-Q-Wave MI): ADULTS: PO Start with a 300 mg loading dose, then continue at 75 mg once daily, initiating and continuing aspirin (75 to 325 mg/day) in combination with clopidogrel.
- Learn more about Clopidogrel ( Plavix 75 mg ) mechanism of action, uses, dosage, side effects, and precautions in this video...
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