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Diltiazem Nursing Considerations, Side Effects, and Mechanism of Action Pharmacology for Nurses
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• 08/18/25
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Diltiazem
Generic Name: diltiazem
Trade Name: Cardizem
Indication: hypertension, angina, SVT, a-fib, aflutter
Action:
inhibits calcium transport resulting in inhibition of excitation and contraction, leads to depression of AV and SA node leading to decreased HR, leads to vasodilatation and decreased blood pressure.
Therapeutic Class: antianginals, antiarrhythmics, antihypertensive
Pharmacologic Class: Ca Channel Blocker (Bezothiazepine)
Nursing Considerations:
contraindicated in 2nd and 3rd AV block
may cause arrhythmias, CHF, bradycardia, peripheral edema, gingival hyperplasia
increases digoxin levels
don't drink grapefruit juice
assess for signs of CHF
monitor EKG continuously
tell patient to change positions slowly
monitor serum potassium
instruct pt on how to take blood pressure
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