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- Adderall
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- Omega 3
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- Tylenol
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- Vitamin B12
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Effexor versus Pristiq: Everything You Need to Know Series
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An overview of venlafaxine (Effexor, Effexor XR) and its active metabolite and FDA-approved medication in its own right, o-desmethylvenlafaxine, or desvenlafaxine (Pristiq). The parent drug differs from its metabolite only in that it is not so quite as potent at blocking the noradrenaline reuptake pump, but both SNRI molecules are more potent at blocking serotonin transporters at all doses (especially lower ones), regardless. Pristiq may also offer more stable plasma levels, due to differences in their pharmacodynamics. Indications, including hot flashes in perimenopause, are reviewed, as are side effects, the sometimes severe discontinuation syndrome, as well as the potential for desvenlafaxine (and therefore, venlafaxine as well) to trigger a false-positive result on immunoassay screening for phencyclidine (PCP) and amphetamines.
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