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Escitalopram vs Vortioxetine: A comparison of two antidepressants
In this video, we compare escitalopram or Lexapro with vortioxetine or Trintellix.
Intro 00:00
How do Escitalopram (Lexapro) and Vortioxetine (Trintellix) work? 00:51
What are Escitalopram (Lexapro) and Vortioxeitn (Trintellix) used for? 01:47
Common side effects of escitalopram (Lexapro) and vortioxetine (Trintelllix) 03:09
Considerations when taking escitalopram (Lexapro) or vortioxetine (Trintellix) 06:20
Final thoughts on escitalopram (Lexapro) and vortioxetine (Trintellix) 08:59
Resources:
Deprescribing Guide: https://amzn.to/4dZEUMk
Stahl's Prescribing Guide: https://amzn.to/3UXj8QL
🎥 This video was edited by:
Rahul Kanchi https://www.linkedin.com/in/rahulkanchi24/
🚑 If you are in a mental health crisis, please dial 9-8-8 from the U.S. Or text HOME to 741741 and connect to a crisis counselor.
You can find a list of international crisis lines here: https://blog.opencounseling.com/suicide-hotlines/
References:
Baune BT, Brignone M, Larsen KG. A Network Meta-Analysis Comparing Effects of Various Antidepressant Classes on the Digit Symbol Substitution Test (DSST) as a Measure of Cognitive Dysfunction in Patients with Major Depressive Disorder. Int J Neuropsychopharmacol. 2018 Feb 1;21(2):97-107. doi: 10.1093/ijnp/pyx070. PMID: 29053849; PMCID: PMC5793828.
Citrome L. (2016). Vortioxetine for major depressive disorder: An indirect comparison with duloxetine, escitalopram, levomilnacipran, sertraline, venlafaxine, and vilazodone, using number needed to treat, number needed to harm, and likelihood to be helped or harmed. Journal of affective disorders, 196, 225–233. https://doi.org/10.1016/j.jad.2016.02.042
Escitalopram FDA label (2017). Retrieved from https://www.accessdata.fda.gov..../drugsatfda_docs/lab
Jacobsen, P. L., Mahableshwarkar, A. R., Chen, Y., Chrones, L., & Clayton, A. H. (2015). Effect of Vortioxetine vs. Escitalopram on Sexual Functioning in Adults with Well-Treated Major Depressive Disorder Experiencing SSRI-Induced Sexual Dysfunction. The journal of sexual medicine, 12(10), 2036–2048. https://doi.org/10.1111/jsm.12980
Stahl,S. (2017). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 6th Ed. Cambridge University Press.
Vortioxetine (Trintellix). FDA Label (2018). Retrieved from https://www.accessdata.fda.gov..../drugsatfda_docs/lab
Patient Resources
Free Web MD drug interaction tracker https://www.webmd.com/interact....ion-checker/default.
Trintellix Patient Assistance Program
http://www.takeda.us/responsib....ility/patient_assist
Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own health care provider for proper diagnosis and treatment.
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