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Fezolinetant (Veozah) a new drug for hot flashes. A complete review.
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• 08/28/25
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This is a complete drug review of fezolinetant (Veozah), a new prescription medication used to treat hot flashes. It is given as a daily oral tablet, and it is not a hormone. Fezolinetant is a unique, first in class treatment option. It works by blocking the NK3 receptor in the brain, which plays a role in body temperature regulation.
This review will define hot flashes, or vasomotor symptoms (VMS), and will briefly go over both hormonal and non-hormonal treatments that are available.
Fezolinetant’s unique mechanism of action will be fully explained, and its precautions, kinetics, drug interactions, and adverse reactions will be described. The drug’s clinical trials will be outlined, and their results will be summarized.
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