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Gabapentin vs Pregabalin
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• 08/26/25
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Are we underdosing Gabapentin & Pregabalin for Neuropathic Pain?
Let's quickly review the effective dosage to ensure our patients get the relief they need. A low, un-titrated dose often leads to treatment failure.
💡 Key Takeaways from the Reel:
1️⃣ Gabapentin:
Start low (e.g., 300mg HS) but titrate upwards.
The effective therapeutic range for neuropathic pain is 900 mg to 1800 mg/day. A dose of 300-600mg might not be sufficient for many patients.
2️⃣ Pregabalin:
Starting at 75mg is common, but don't stop there.
The effective therapeutic dose is typically 150 mg to 300 mg/day.
Let's ensure we are titrating the dose to the effective range rather than keeping patients on a sub-therapeutic starter dose. Patient response and tolerability are key!
🧠 Your turn, doc! What's the most common side effect you counsel your patients about for these two drugs? Drop your answer in the comments! 👇
#DoctorsOfIndia #MedicalEducation #ClinicalPearls #NeuropathicPain #Gabapentin #Pregabalin #IndianDoctors #PainManagement
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