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Griseofulvin in Dermatology - Agent, Mechanism of Action, Use, Side-effects
Hi. With this video, we will discuss the use of Griseofulvin in Dermatology and be better prepared for treating our patients. This video is directed towards dermatologists and is not at all advisory for non-medical personnel.
Introduction - 01:50
Pharmacology - 05:15
Mechanism of Action - 08:22
Pharmacology: Skin - 14:10
Uses - 17:48
Grisefulvin vs Terbinafine vs Fluconazole in Tinea capitis - 26:00
Algorithm for Tinea capitis - 27:44
Other Fungal Uses - 30:22
Other Non-fungal Uses - 31:35
Contraindications - 33:33
Adverse Events - 35:10
Drug Interactions - 37:03
Pregnancy and Lactation - 38:52
Monitoring - 40:30
Further Reading - 42:02
End - 42:49
Good articles on Griseofulvin:
1. Griofulvin. Product Insert. URL::https://www.accessdata.fda.gov..../drugsatfda_docs/lab
2. Olson JM, Troxell T. Griseofulvin. In: StatPearls. Treasure Island (FL): StatPearls Publishing; July 31, 2023.
3. Grover C, Arora P, Manchanda V. Comparative evaluation of griseofulvin, terbinafine and fluconazole in the treatment of tinea capitis. Int J Dermatol. 2012;51(4):455-458. doi:10.1111/j.1365-4632.2011.05341.x
4. Maruani A, Barbarot S, Gangneux JP, et al. Management of tinea capitis in children following the withdrawal of griseofulvin from the French market: A fast-track algorithm proposed by the Center of Evidence of the French Society of Dermatology. Ann Dermatol Venereol. 2022;149(4):238-240. doi:10.1016/j.annder.2022.07.001
5. Mulay DN, Mehta JS, Ahuja BB, Raizada AK. Use of Griseofulvin Other Than Anti-fungal. Indian J Dermatol Venereol. 1969;35(2):78-82.
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