How and When to use Nitrofurantoin? (Macrobid, Macrodantin)

How and When to use Nitrofurantoin? (Macrobid, Macrodantin) - Doctor Explains

3 Views • 08/24/25

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This is the third video I made on antibiotics. I already made a video on amoxicillin and augmentin. You can find those video’s here:
Amoxicillin: https://youtu.be/z_FVq2x3uxI
Augmentin: https://youtu.be/5mwmVh6xVY4

Everything on Antibiotics playlist:
https://www.youtube.com/playli....st?list=PLaG3Bo3L0gX

In this video we will focus on how and when to use Nitrofurantoin.
Generic name: Nitrofurantoin.
Brand names: Macrobid, Macrodantin, Furabid and Furadantine.
Available as: powder for oral suspension and capsules

How to use it?
Swallow the capsule whole with half a glass of water or resolve the powder in half a glass of water. Make sure to eat something after taking nitrofurantoin and take it at fixed times.
It is important to note that you should not interrupt the treatment and that you have to finish it completely.

When to use it?
Use it to treat acute low urinary tract infections

What is the correct dose?
For adults and children older than 12 years:
Regular capsules or suspensions: 50 mg 4×/day
Modified-release capsules:100 mg 2x/day.
The treatment duration is usually 5 days for non-pregnant women and 7 days for pregnant women or men.

-Always used your prescribed dosage and frequency!-

Side effects:
Very common ( more than10%):
Superinfection, High blood pressure in your brain, Short-term spot baldness.
Rare (0.01–0.1%):
Collapse, cyanosis, inflammation of your liver, nausea, loss of appetite, anaemia, skin problems.

Safety:
You can combine nitrofurantoin with any type of food and even with alcohol.
But don’t use this medication when you have severe renal impairment or if you are hypersensitive to nitrofurans.

Pregnancy and Lactation:
You can safely use nitrofurantoin if you are pregnant or breastfeeding.
However, you should avoid it in the last 30 days of pregnancy.

- Disclaimer: this video is meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. -

Thanks for watching, and make sure to subscribe for future videos on medication and medical topics!

Literature:
1: Farmacotherapeutisch Kompas. (2020). Nitrofurantoine.
2: Apotheek.nl. (2020). Nitrofurantoine.
3. Sinha S. (2020). Nitrofurantoin.

* The images in this video are used for educational purposes only.

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1. Huma-Huma, Crimson Fly
2. DivKid, Dusk
3. Ikson, New Day

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Lehninger Principles of Biochemistry Seventh Edition, https://amzn.to/2PFGidh
Guyton and Hall Textbook of Medical Physiology 14th Edition, https://amzn.to/3inL6jM
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Oxford Handbook of Clinical Specialties, https://amzn.to/3fU854s
Oxford Handbook of Emergency Medicine, https://amzn.to/31LfMVg
Oxford Handbook of Clinical Medicine, https://amzn.to/3ky73hZ
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Atlas of Human Anatomy (Netter Basic Science), https://amzn.to/3afFe9c
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