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How do Factor Xa Inhibitors Work? (DOAC's)
How do Factos XA inhbitors (Rivaroxaban) Work? These factor xa inhibitors are anticoagulants that block clotting factor 10 to which prevent the production of fibirin. This causes a decrease in blood clots and ultimately "thins" the blood.
There are 4 drugs in this class: Rivaroxaban, Apixaban, Edoxaban & Betrixaban. They are all anticoagulants These medications are used to treat and prevent blood clots from forming which may lead to heart attack and stroke patients. Anticoagulant therapy seeks to prevent the development of deep vein thrombosis and pulmonary embolisms.
Time Stamps:
- Intro 00:00
- Breakdown 00:22
- Factor Xa Inhibitor Overview 00:31
- Mechanism of Action 03:30
- When to use 06:22
- Dosing & Adjustments 08:05
- Clinical pearls & Side effects 11:29
- Quick Summary 12:27
- Short Quiz 14:04
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Answers:
1.)D
2.)D
3.)C
4.)A
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This pharmacology lecture covers topics such as Anticoagulant drugs. We talk about Rivaroxaban, Apixaban, Edoxaban & Betrixaban. We discuss how these drugs help block the clotting factors 10 which leads to less fibrin being formed. This causes the lowering of blood clots. Also, we talk about the pathophysiology of the clotting cascade, heart attack and stroke and how anti-coagulation therapy is beneficial. We discuss the mechanism of action of these DOAC's and their side effects. Brand name of these medications include: Xarelto, Eliquis, Savaysa & Bevyxxa
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