How does Taltz compare to Cosentyx for psoriatic arthritis Taltz and Cosentyx are similar in the way they work their side effects and their potential for interactions but Taltz does appear to provide patients with psoriatic arthritis PA with more qualityadjusted lifeyears QALYs compared with Cosentyx at a marginally lower cost Cosentyx may have a quicker onset of effectBoth Taltz and Cosentyx may be used to treat adults with psoriatic arthritis but Cosentyx is also approved for children with psoriatic arthritis over the age of years They both belong to the same class of medicines called interleukin inhibitors and work in the same way that is to selectively bind to interleukin A ILA to reduce inflammation Interleukin inhibitors are considered a breakthrough in psoriasis and psoriatic arthritis treatment because research has discovered that immune cell TH was a major cause of psoriasis and that interleukinA was the most abundant cytokine produced by TH cellsSide effects of Cosentyx and Taltz that are similar include infections such as those affecting the lungs nose or skin or a stuffy or runny nose Cosentyx is more likely to cause nasopharyngitis diarrhea oral herpes and urticaria and Taltz is more likely to cause nausea and has a higher incidence of injection site reactionsInteractions with medicines such as immunosuppressants warfarin and live vaccines are similar with Cosentyx and TaltzBoth are injections that need to be stored in the refrigerator at C to C F to F before useBoth start working within a few weeks but it may take up to months for the full effects of Cosentyx to be seen and up to months for the full effects of Taltz to developBoth Taltz and Cosentyx are associated with an increased risk of developing inflammatory bowel disease Report any symptoms such as diarrhea abdominal pain fever blood in the stool or weight loss to your doctorDifferences in effectivenessVery few studies have directly compared Cosentyx with Taltz with regards to psoriatic arthritis Taltz provided more qualityadjusted lifeyears QALYs compared with Cosentyx to patients with psoriatic arthritis PsA and concomitant moderate to severe plaque psoriasis at a marginally lower cost in one study published in PharmacoEconomicsAnother study that investigated patients with psoriasis reported that Cosentyx and Taltz were both highly effective in the short and longterm treatment of psoriasis but that Cosentyx had a more rapid onset and Taltz longer effectivenessOther differencesOther differences between Cosentyx and Taltz includeCosentyx is a brand trade name for secukinumab and Taltz is a brand trade name for ixekizumab Both are interleukin inhibitorsCosentyx is available as a Sensoready pen and prefilled syringe and an IV formulation that can be administered over minutes by a healthcare provider Taltz is available as the Taltz Autoinjector and the Taltz prefilled syringe People can be taught how to selfadminister the prefilled pens syringes and autoinjectorsCosentyx for self administration requires two injections per dose to be given because each injection is only mg and mg is the usual dose Cosentyx given by an IV infusion in your healthcare providers office is given into a vein over approximately minutesApart from the very first dose of Taltz which requires two mg injections to make mg every other dose of Taltz is just one injection of mgThe recommended dose of Cosentyx is mg by subcutaneous injection at Weeks and followed by mg every weeksThe recommended dose of Taltz is mg two mg injections at Week followed by mg at Weeks and then mg every weeksCosentyx should be thrown away if stored unrefrigerated for a single period of more than days at room temperature not above C Taltz can remain out of the refrigerator for up to five days at room temperature not above CNatural rubber latex is contained in the removable cap of the Cosentyx Sensoready pen and the Cosentyx prefilled syringe This may cause an allergic reaction in latexsensitive individuals if they handle the cap Taltz injections do not contain latexRelated questions What does psoriasis look like How do you get psoriasis and is it contagious How does Tremfya work to treat plaque and psoriatic arthritis

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