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How Long Should Tocilizumab Be Continued for Patients with Giant Cell Arteritis?
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• 08/29/25
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"Giant cell arteritis, is a disease that has huge unmet need ever since cortisone was invented 67 years ago," said John Stone, MD, Massachusetts General Hospital. Stone explained that the only existing treatment, glucocorticoids (prednisone), while effective, is associated with a host of side effects, making it difficult to maintain patients on prednisone for a long period of time. Stone and his team embarked on the GIACTA study, whose goal was to demonstrate that tocilizumab had a powerful "steroid-sparing" effect. To test their hypothesis, the team embarked on a trial with four arms and 251 patients.
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