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How to treat hormonal acne with spironolactone in 2025: dermatologist and acne expert explains
I'm John Barbieri, MD, a board-certified dermatologist and acne expert at the Brigham and Women’s Hospital and Harvard Medical School. In this video we will discuss how the role of hormones in acne, how spironolactone can treat acne, and appropriate use spironolactone, including the best dose and common side effects.
#acne #hormones #spironolactone #acnetreatment #dermatologist #expert
Chapters:
0:00 - Intro
0:19 - Role of hormones in acne
0:57 - How spironolactone works
1:36 - Dosing
3:26 - Side effects
4:32 - Spironolactone and cancer risk
4:53 - Potassium monitoring
5:53 - Spironolactone and athletics
6:16 - Comparison with antibiotics and isotretinoin
7:56 - Clascoterone (Winlevi)
References:
SAFA Trial: https://pubmed.ncbi.nlm.nih.gov/37192767/
Dosing: https://pubmed.ncbi.nlm.nih.gov/6235834/; https://pubmed.ncbi.nlm.nih.gov/33434594/
Cancer risk: https://pubmed.ncbi.nlm.nih.gov/35138351/
Hyperkalemia and potassium monitoring: https://pubmed.ncbi.nlm.nih.gov/25796182/; https://pubmed.ncbi.nlm.nih.gov/31360748/; https://pubmed.ncbi.nlm.nih.gov/22208934/
Spironolactone vs oral antibiotics: https://pubmed.ncbi.nlm.nih.gov/29879250/
Spironolactone after isotretinoin: https://pubmed.ncbi.nlm.nih.gov/28862134/
Clascoterone: https://pubmed.ncbi.nlm.nih.gov/32320027/
Twitter/Instagram: @DrJohnBarbieri
Thumbnail credit: Sherry Ershadi
Disclaimer:
This YouTube Channel does not provide any diagnosis, treatment or medical advice and does not replace a visit to your doctor. The statements are not intended to treat, diagnose, cure or prevent disease. See your doctor for medical advice and treatment. My statements on this channel are for informational purposes only.
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